Zobrazeno 1 - 10
of 617
pro vyhledávání: '"Larry E. Overman"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background Pancreatic cancer is one of the most lethal malignancies due to frequent late diagnosis, aggressive tumor growth and metastasis formation. Continuously raising incidence rates of pancreatic cancer and a lack of significant improve
Externí odkaz:
https://doaj.org/article/775e342262fb4d19bdec5506257b69f1
Autor:
Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullie, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey R.J. Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, Jason M. Rohde
Publikováno v:
ACS Central Science, Vol 4, Iss 12, Pp 1727-1741 (2018)
Externí odkaz:
https://doaj.org/article/9f2975f36dd648f0b92b6e0f2b27c087
Autor:
Kendall N. Houk, Quan Tran, Larry E. Overman, Michael B. Shaghafi, Pan-Pan Chen, Tyler K. Allred
Publikováno v:
Organic Letters. 23:7618-7623
We report that structurally complex guanidinium heterocycles can be prepared in one step by regio- and stereoselective [4 + 2]-cycloadditions of N-amidinyliminium ions with indoles or benzothiophene. In contrast to reactions of these heterodienes wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5ba639437b79be48859f319fd643b8
https://doi.org/10.1021/acs.orglett.1c02832
https://doi.org/10.1021/acs.orglett.1c02832
Autor:
Larry E. Overman, Spencer P. Pitre
Publikováno v:
Chemical Reviews. 122:1717-1751
Recent progress in the development of photocatalytic reactions promoted by visible light is leading to a renaissance in the use of photochemistry in the construction of structurally elaborate organic molecules. Because of the rich functionality found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ec9c49eb2da8af8fdcafe3d29898a3
https://doi.org/10.1021/acs.chemrev.1c00247
https://doi.org/10.1021/acs.chemrev.1c00247
Publikováno v:
The Journal of Organic Chemistry. 85:15532-15551
The evolution of a strategy to access the family of rearranged spongian diterpenoids harboring a concave-substituted cis-2,8-dioxabicyclo[3.3.0]octan-3-one fragment is described. The approach involves late-stage fragment coupling of a tertiary-carbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a727c081d23a284fd8264d924dfd115
https://doi.org/10.1021/acs.joc.0c02273
https://doi.org/10.1021/acs.joc.0c02273
Publikováno v:
Angew Chem Int Ed Engl
The enantioselective total synthesis of the rearranged spongian diterpenoid (–)-macfarlandin C is reported. This is the first synthesis of a rearranged spongian diterpenoid in which the bulky hydrocarbon fragment is joined via a quaternary carbon t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad389bdf617eead46761f925d2d450d
https://doi.org/10.1002/ange.201916753
https://doi.org/10.1002/ange.201916753
Publikováno v:
Cancers, Vol 13, Iss 6151, p 6151 (2021)
There is an omission in the Institutional Review Board Statement and Conflict of Interest statements of the paper [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b2a1ce759fdc3a9ce7315801c54b4c
https://www.mdpi.com/2072-6694/13/24/6151
https://www.mdpi.com/2072-6694/13/24/6151
Publikováno v:
Organic letters. 23(19)
We report that structurally complex guanidinium heterocycles can be prepared in one step by regio- and stereoselective [4 + 2]-cycloadditions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5e79acc61d9d7771fe4ec9295bbc319
https://pubmed.ncbi.nlm.nih.gov/34546759
https://pubmed.ncbi.nlm.nih.gov/34546759
Publikováno v:
Cancers, Vol 13, Iss 3367, p 3367 (2021)
Cancers
Cancers, vol 13, iss 13
Volume 13
Issue 13
Cancers
Cancers, vol 13, iss 13
Volume 13
Issue 13
Simple Summary Cutaneous T cell lymphomas (CTCLs) are a group of blood cancers that cannot be cured with current chemotherapeutical or biological drugs. Patients with advanced disease are severely immunocompromised due to the unchecked expansion of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38250124faf9329019011435f288006c
https://www.mdpi.com/2072-6694/13/13/3367
https://www.mdpi.com/2072-6694/13/13/3367
Publikováno v:
Angewandte Chemie. 131:8649-8653
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e14a4b2da4a3ce953b2fe74bc4b0761
https://doi.org/10.1002/ange.201903353
https://doi.org/10.1002/ange.201903353