Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Larry Denner"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
A major aspect of mammalian aging is the decline in functional competence of many self-renewing cell types, including adult-born neuronal precursors in a process termed neurogenesis. Adult neurogenesis is limited to specific brain regions in the mamm
Externí odkaz:
https://doaj.org/article/f3f62af7adfb4e1c951b47293c7f4a18
Publikováno v:
Neurobiology of Disease, Vol 72, Iss , Pp 92-103 (2014)
Insulin is a key hormone regulating metabolism. Insulin binding to cell surface insulin receptors engages many signaling intermediates operating in parallel and in series to control glucose, energy, and lipids while also regulating mitogenesis and de
Externí odkaz:
https://doaj.org/article/de99f3b2865e480993aa325d75f2553d
Autor:
Nathaniel G. Girer, Dwayne Carter, Nisha Bhattarai, Mehnaz Mustafa, Larry Denner, Craig Porter, Cornelis J. Elferink
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 950 (2019)
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor highly expressed in hepatocytes. Researchers have employed global and liver-specific conditional Ahr knockout mouse models to characterize the physiological roles of the A
Externí odkaz:
https://doaj.org/article/6d76d86fc9614ac88abf167fc60fbe1a
Autor:
Jonathan M Starkey, Yingxin Zhao, Rovshan G Sadygov, Sigmund J Haidacher, Wanda S Lejeune, Nilay Dey, Bruce A Luxon, Maureen A Kane, Joseph L Napoli, Larry Denner, Ronald G Tilton
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11095 (2010)
Numerous metabolic pathways have been implicated in diabetes-induced renal injury, yet few studies have utilized unbiased systems biology approaches for mapping the interconnectivity of diabetes-dysregulated proteins that are involved. We utilized a
Externí odkaz:
https://doaj.org/article/540f78890a5d40b1ae89d76170f39b9f
Autor:
Sabin A. Nettles, Katherine Warre-Cornish, Marc J. Tetel, Larry Denner, Lucia Dutan Polit, Deepak Srivastava, Cheryl F. Lichti, Kalpana D. Acharya
Publikováno v:
J Neuroendocrinol
Neural progestin receptors (PR) function in reproduction, neural development, neuroprotection, learning, memory and the anxiety response. In the absence of progestins, PR can be activated by dopamine (DA) in the rodent hypothalamus to elicit female s
Autor:
Larry Denner, Robert G. Fox, Kathryn A. Cunningham, Scott D. Lane, Kelly T. Dineley, Sonja J. Stutz, William R Miller
Publikováno v:
Addiction Biology. 23:55-68
Cocaine use disorder is a chronic relapsing condition characterized by compulsive drug seeking and taking even after prolonged abstinence periods. Subsequent exposure to drug-associated cues can promote intense craving and lead to relapse in abstinen
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 11 (2019)
Frontiers in Aging Neuroscience, Vol 11 (2019)
A major aspect of mammalian aging is the decline in functional competence of many self-renewing cell types, including adult-born neuronal precursors in a process termed neurogenesis. Adult neurogenesis is limited to specific brain regions in the mamm
Publikováno v:
Journal of Alzheimer's disease : JAD. 64(s1)
Insulin resistance can occur when the body is unable to respond to insulin even in excess. In the brain, insulin manages glucose metabolism in regions such as the hippocampus and plays a key role in directly regulating ERK, a kinase required for the
Publikováno v:
Journal of Neurophysiology
Early cognitive impairment in Alzheimer's disease (AD) correlates with medial temporal lobe dysfunction, including two areas essential for memory formation: the entorhinal cortex and dentate gyrus (DG). In the Tg2576 animal model for AD amyloidosis,
Publikováno v:
Neurobiology of Disease, Vol 72, Iss, Pp 92-103 (2014)
Insulin is a key hormone regulating metabolism. Insulin binding to cell surface insulin receptors engages many signaling intermediates operating in parallel and in series to control glucose, energy, and lipids while also regulating mitogenesis and de