Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Larry D. Kier"'
Publikováno v:
Critical Reviews in Toxicology. 46:56-74
In 2015, the International Agency for Research on Cancer (IARC) published a monograph concluding there was strong evidence for genotoxicity of glyphosate and glyphosate formulations and moderate evidence for genotoxicity of the metabolite aminomethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d05511d3a2f449497fe55a7c583145
https://doi.org/10.1080/10408444.2016.1214680
https://doi.org/10.1080/10408444.2016.1214680
Autor:
João Lauro Viana de Camargo, Douglas L. Weed, Gary M. Williams, David H. Garabrant, Keith R. Solomon, Marilyn J. Aardema, Sir Colin Berry, David Kirkland, Michele M. Burns, John F. Acquavella, Larry D. Kier, Tom Sorahan, Ashley Roberts, Helmut Greim, David Brusick, Gary M. Marsh
Publikováno v:
Critical Reviews in Toxicology. 46:3-20
The International Agency for Research on Cancer (IARC) published a monograph in 2015 concluding that glyphosate is "probably carcinogenic to humans" (Group 2A) based on limited evidence in humans and sufficient evidence in experimental animals. It wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89929fbea04790f0495feb467903ab06
https://doi.org/10.1080/10408444.2016.1214677
https://doi.org/10.1080/10408444.2016.1214677
Autor:
Larry D. Kier
Publikováno v:
Critical Reviews in Toxicology
Human and environmental genotoxicity biomonitoring studies involving exposure to glyphosate-based formulations (GBFs) were reviewed to complement an earlier review of experimental genotoxicity studies of glyphosate and GBFs. The environmental and mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac7dd21baca8f4ad022819f93ef1efe
https://doi.org/10.3109/10408444.2015.1010194
https://doi.org/10.3109/10408444.2015.1010194
Autor:
David Kirkland, Larry D. Kier
Publikováno v:
Critical Reviews in Toxicology. 43:283-315
An earlier review of the toxicity of glyphosate and the original Roundup™-branded formulation concluded that neither glyphosate nor the formulation poses a risk for the production of heritable/somatic mutations in humans. The present review of subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5581a194019bf4139e9e7aa9c2ca45ce
https://doi.org/10.3109/10408444.2013.770820
https://doi.org/10.3109/10408444.2013.770820
Autor:
Donna R. Farmer, Charles E. Healy, Alan G. E. Wilson, William F. Heydens, Mark A. Martens, Kathy J. Hotz, Larry D. Kier
Publikováno v:
Journal of Agricultural and Food Chemistry. 56:1517-1523
A broad array of in vitro and in vivo assays has consistently demonstrated that glyphosate and glyphosate-containing herbicide formulations (GCHF) are not genotoxic. Occasionally, however, related and contradictory data are reported, including findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beacb65d9a938e138fef6d8fa4c110ba
https://doi.org/10.1021/jf072581i
https://doi.org/10.1021/jf072581i
Autor:
Jeffrey A. Kramer, Larry D. Kier, Carl L. Alden, Eric A.G. Blomme, Sandra W. Curtiss, Roderick T. Bunch, Kyle L. Kolaja, Mollisa M. Elrick, Marc A. Cabonce, Charles P. Rodi, Dale L. Morris
Publikováno v:
Toxicologic Pathology. 33:118-126
Hepatic enzyme inducers such as phenobarbital are often nongenotoxic rodent hepatocarcinogens. Currently, nongenotoxic hepatocarcinogens can only be definitively identified through costly and extensive long-term, repeat-dose studies (e.g., 2-year rod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155b8e2e67b95f0f55842939b9260a62
https://doi.org/10.1080/01926230590888298
https://doi.org/10.1080/01926230590888298
Autor:
Robin E. Neft, Tim Nolan, Albert P. Li, Kathy Onsurez, Yumiko Sakai, Larry D. Kier, Robert Suizu, Michael Ortiz, Usha Sankar, Lei Tang, Karen Tiegler, Tari Cook
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 549:101-113
Microarrays with toxicologically relevant genes (tox genes) have been developed in our laboratory for toxicogenomics studies in rat, dog and man. The genes were chosen using published information as well as a discovery process for genes responsive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d684e0ed5adc95487711579a83296205
https://doi.org/10.1016/j.mrfmmm.2003.11.015
https://doi.org/10.1016/j.mrfmmm.2003.11.015
Publikováno v:
International Journal of Toxicology. 22:233-251
Triallate is a selective herbicidal chemical used for control of wild oats in wheat. It has an extensive genotoxicity database that includes a variety of in vitro and in vivo studies. The chemical has produced mixed results in in vitro assay systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72762e2f3545e741a41dda899f8ddbe7
https://doi.org/10.1080/10915810305112
https://doi.org/10.1080/10915810305112
Publikováno v:
Regulatory Toxicology and Pharmacology. 33:356-362
Schizochytrium sp. dried microalgae (DRM) contains oil rich in highly unsaturated fatty acids (PUFAs). Docosahexaenoic acid (DHA n-3) is the most abundant PUFA component of the oil. DHA-rich oil extracted from Schizochytrium sp. is intended for use a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a955c9dc14dc3dc51c8399c78e189652
https://doi.org/10.1006/rtph.2001.1477
https://doi.org/10.1006/rtph.2001.1477
Publikováno v:
Drug and Chemical Toxicology. 18:29-41
Cytotoxicity was measured in vitro for 8 ethylene oxide/propylene oxide copolymers (EO/PO copolymers) using lactate dehydrogenase release from cultured mammalian cells as the endpoint. Three cell types were used in these assays: Chinese hamster ovary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259bb02a677238e30d567170c6c01836
https://doi.org/10.3109/01480549509017856
https://doi.org/10.3109/01480549509017856