Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Larry D. Calder"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 61:435-443
In previous studies we demonstrated that dopamine, specifically a D2-receptor system, in the frontal cortex of the mouse functions to inhibit the motor response elicited by systemically administered amphetamine or cocaine; the inhibition appears to b
Publikováno v:
Pharmacology Biochemistry and Behavior. 60:237-244
The results of previous studies have indicated that the activation of dopaminergic and GABAergic systems in the prefrontal cortex can decrease dopaminergic and glutamatergic activity in the striatum, ostensibly by the inhibition of corticofugal gluta
Publikováno v:
Psychopharmacology. 124:219-225
The present experiments were designed to compare the properties of behavioral sensitization induced by the indirect agonists, amphetamine and cocaine, to that induced by the direct dopamine agonists, apomorphine and PPHT. Both classes of agonist prod
Autor:
Ralph Karler, Larry D. Calder
Publikováno v:
Brain Research. 582:143-146
Antagonists of theN-methyl- d -aspartate (NMDA) type of excitatory amino acid (EAA) receptors blocked cocaine-induced stereotypy, locomotor stimulation and convulsions. These effects in general appear to involve selectively NMDA type of receptors. Th
Publikováno v:
Brain Research. 537:76-82
The effects of 8 selective neuroeffector agonists and antagonists were measured in mice in order to identify specific functional changes associated with behavioral sensitization to amphetamine-induced stereotypy. The changes observed included a decre
Publikováno v:
Life Sciences. 46:1773-1780
Repeated intermittent administration of amphetamine in mice caused reverse tolerance to 5-hydroxy-L-tryptophan (5-HTP)-induced head twitch, as well as to amphetamine-induced stereotypy. The repeated administration of 5-HTP alone also resulted in reve
Publikováno v:
Pharmacology, biochemistry, and behavior. 56(2)
Previous results of pharmacological studies of the mechanisms of amphetamine- and cocaine-induced stereotypy in the mouse suggest the involvement of dopaminergic, glutamatergic and GABAergic systems in the striatum. The present experiments were desig
Publikováno v:
Brain research. 671(1)
The present experiments were designed to evaluate pharmacologically the role of three neuroanatomically related systems--dopamine, glutamate and GABA--in the motor-stimulant response to amphetamine and cocaine. The data indicate that stimulant-induce
Publikováno v:
Brain research. 658(1-2)
The behavioral effects of amphetamine and cocaine are generally considered to be the result of their indirect dopaminergic activity. Recent reports, however, suggest that the activity of the psychomotor stimulants involves not only the dopaminergic b