Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Larry D, Sanford"'
Autor:
Minlan Yuan, Biao Yang, Gerson Rothschild, J. John Mann, Larry D. Sanford, Xiangdong Tang, Canhua Huang, Chuang Wang, Wei Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-30 (2023)
Abstract Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease that affects an estimated 300 million people worldwide, but its pathogenesis is poorly understood. The heritability estimate of MDD is 30–40%, sugges
Externí odkaz:
https://doaj.org/article/72b6d04ee5ad44d9a05ab84555fabe92
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Increasing evidence has connected the development of certain neuropsychiatric disorders, as well as neurodegenerative diseases, to stress-induced dysregulation of the immune system. We have shown that escapable (ES) and inescapable (IS) foot
Externí odkaz:
https://doaj.org/article/719fce89772547e7b7010269754e5731
Autor:
Austin M. Adkins, Zachary N. M. Luyo, Alayna J. Gibbs, Alea F. Boden, Riley S. Heerbrandt, Justin D. Gotthold, Richard A. Britten, Laurie L. Wellman, Larry D. Sanford
Publikováno v:
Life, Vol 14, Iss 5, p 636 (2024)
The proposed Mars missions will expose astronauts to long durations of social isolation (SI) and space radiation (SR). These stressors have been shown to alter the brain’s macrostructure and microenvironment, including the blood–brain barrier (BB
Externí odkaz:
https://doaj.org/article/8c1eb061cbca4d91b0e433fcb5310e4e
Autor:
Ye Zhang, Rong Ren, Linghui Yang, Haipeng Zhang, Yuan Shi, Hamid R. Okhravi, Michael V. Vitiello, Larry D. Sanford, Xiangdong Tang
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Polysomnography (PSG) studies of sleep changes in Alzheimer’s disease (AD) have reported but not fully established the relationship between sleep disturbances and AD. To better detail this relationship, we conducted a systematic review and
Externí odkaz:
https://doaj.org/article/10ea97246cfd4d6583feb8751c43ccd8
Autor:
Larry D. Sanford, Laurie L. Wellman, Austin M. Adkins, Ming-Lei Guo, Ye Zhang, Rong Ren, Linghui Yang, Xiangdong Tang
Publikováno v:
Neurobiology of Stress, Vol 23, Iss , Pp 100517- (2023)
Sleep and stress have complex interactions that are implicated in both physical diseases and psychiatric disorders. These interactions can be modulated by learning and memory, and involve additional interactions with the neuroimmune system. In this p
Externí odkaz:
https://doaj.org/article/69e62b7d2d2547099be7c24002d13dea
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Previous studies on the association of insomnia with body mass index (BMI) have been controversial. Physiological hyperarousal, the key pathological mechanism of insomnia, may be an important reason for different findings. We explored whethe
Externí odkaz:
https://doaj.org/article/5e0f3e2c09f146d49d52243fd097662f
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
BackgroundTranscriptome-wide analysis of peripheral blood in post-traumatic stress disorder (PTSD) indicates widespread changes in immune-related pathways and function. Ferroptosis, an iron-dependent regulated cell death, is closely related to oxidat
Externí odkaz:
https://doaj.org/article/f2b0f66ab2c34938aba46deb3418c9b7
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 100 (2023)
Background: Training with inescapable shock (IS; uncontrollable stressor) is followed by significant decreases in rapid eye movement sleep (REM). However, controllability is important in the effects of stress. We examined the effects of escapable sho
Externí odkaz:
https://doaj.org/article/365b274d5cf24b8aa7f55e1ec394bc7d
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Obstructive sleep apnea (OSA) is a worldwide health issue that affects more than 400 million people. Given the limitations inherent in the current conventional diagnosis of OSA based on symptoms report, novel diagnostic approaches are required to com
Externí odkaz:
https://doaj.org/article/2ec727a029064bdeb200605d6be6403b
Autor:
Yan Cheng, Rachael Elizabeth Dempsey, Soheil Kazemi Roodsari, Dorela D. Shuboni-Mulligan, Olivier George, Larry D. Sanford, Ming-Lei Guo
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1800 (2023)
Cocaine, one of the most abused drugs worldwide, is capable of activating microglia in vitro and in vivo. Several neuroimmune pathways have been suggested to play roles in cocaine-mediated microglial activation. Previous work showed that cocaine acti
Externí odkaz:
https://doaj.org/article/a40d084bc3b84597a4d7ece0b278d7a1