Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Larry D, Bozulic"'
Autor:
Hong Xu, Jun Yan, Ziqiang Zhu, Lala-Rukh Hussain, Yiming Huang, Chuanlin Ding, Larry D. Bozulic, Yujie Wen, Suzanne T. Ildstad M.D.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
We show for the first time that signaling through the TLR4/TRIF pathway plays a critical role in allogeneic bone marrow cell (BMC) rejection. This appears to be unique to BMCs as organ allografts are rejected mainly via MyD88 signaling. Using T- or T
Externí odkaz:
https://doaj.org/article/edf3ab65c24748378552033ebebf2481
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Successful hand and face transplantation in the last decade has firmly established the field of vascularized composite allotransplantation (VCA). The experience in VCA has thus far been very similar to solid organ transplantation in terms of the morb
Externí odkaz:
https://doaj.org/article/528ed9632ec84a71b569835aacb49cfc
Autor:
Yujie Wen, Esma S. Yolcu, Larry D. Bozulic, He Xu, Yiming Huang, Thomas Miller, Mary Jane Elliott, Mariusz Z. Ratajczak, Suzanne T. Ildstad, Janina Ratajczak
Publikováno v:
American Journal of Transplantation. 16:440-453
CD8(+)/TCR(-) facilitating cells (FCs) in mouse bone marrow (BM) significantly enhance engraftment of hematopoietic stem/progenitor cells (HSPCs). Human FC phenotype and mechanism of action remain to be defined. We report, for the first time, the phe
Autor:
James M. Mathew, Joseph R. Leventhal, Iwona M. Konieczna, Esma S. Yolcu, Michael Abecassis, Jayesh Mehta, Joshua Miller, Larry D. Bozulic, Michael G. Ison, David J. Tollerud, Suzanne T. Ildstad, Mark D. Badder, Mary Jane Elliott, John P. Galvin, Lorenzo Gallon
Publikováno v:
Transplantation. 99:288-298
Nineteen subjects have more than 18 months' follow-up in a phase IIb tolerance protocol in HLA-mismatched recipients of living donor kidney plus facilitating cell enriched hematopoietic stem cell allografts (FCRx). Reduced intensity conditioning prec
Publikováno v:
Transplantation Journal. 95:301-308
Approaches to safely induce tolerance in vascularized composite allotransplantation (VCA) with chimerism through bone marrow transplantation (BMT) are currently being pursued. However, VCA was historically performed sequentially after donor chimerism
Autor:
Hong Xu, Larry D. Bozulic, Lala-Rukh Hussain, Jun Yan, Yiming Huang, Ziqiang Zhu, Suzanne T. Ildstad
Publikováno v:
Transplantation. 93:469-476
Background Mixed chimerism is an effective approach for tolerance induction in transplantation. Strategies to achieve mixed chimerism with relatively low toxicity have significantly expanded the clinical use of chimerism.
Autor:
Hong Xu, Yiming Huang, Larry D. Bozulic, Suzanne T. Ildstad, Thomas Miller, Lala-Rukh Hussain
Publikováno v:
Blood. 117:2494-2505
CD8-positive/T-cell receptor–negative (CD8+/TCR−) graft facilitating cells (FCs) are a novel cell population in bone marrow that potently enhance engraftment of hemopoietic stem cells (HSCs). Previously, we showed that the CD11c+/B220+/CD11b− p
Autor:
Larry D. Bozulic, Yiming Huang, Ziqiang Zhu, Chuanlin Ding, Hong Xu, Jun Yan, Suzanne T. Ildstad, Lala Rukh Hussain
Publikováno v:
American Journal of Transplantation. 10:1569-1579
Sensitization to major histocompatibility complex (MHC) alloantigens is critical in transplantation rejection. The mechanism of sensitization to minor histocompatibility antigens (Mi-HAg) has not been thoroughly explored. We used a mouse model of all
Autor:
Larry D. Bozulic, Yiming Huang, Paula M. Chilton, Mary Jane Elliott, Suzanne T. Ildstad, Hong Xu, Thomas Miller, Isabelle Fugier-Vivier
Publikováno v:
Diabetes
OBJECTIVE—Plasmacytoid precursor dendritic cell facilitating cells (p-preDC FCs) play a critical role in facilitation of syngeneic and allogeneic hematopoietic stem cell (HSC) engraftment. Here, we evaluated the phenotype and function of CD8+/TCR
Autor:
Suzanne T. Ildstad, Warren C. Breidenbach, He Xu, Kadiyala V. Ravindra, Larry D. Bozulic, S. Wu
Publikováno v:
Transplantation Proceedings. 40:1237-1248
Composite tissue allotransplantation (CTA) is emerging as a potential treatment for complex tissue defects. It is currently being performed with increasing frequency in the clinic. The feasibility of the procedure has been confirmed through 30 hand t