Melatonin, a Potential Therapeutic Agent for Preeclampsia, Reduces the Extrusion of Toxic Extracellular Vesicles from Preeclamptic Placentae

Autor: Yunhui Tang, Katie Groom, Larry Chamley, Qi Chen

Publikováno v: Cells, Vol 10, Iss 8, p 1904 (2021)

Preeclampsia, characterised by maternal endothelial cell activation, is triggered by toxic factors, such as placental extracellular vesicles (EVs) from a dysfunctional placenta. The increased oxidative stress seen in the preeclamptic placenta links t

Externí odkaz: https://doaj.org/article/daeba2b487154b5abc0dc6c69179f4f0

The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier

Autor: Joy N. Reginald-Opara, Mingtan Tang, Darren Svirskis, Larry Chamley, Zimei Wu

Publikováno v: International journal of pharmaceutics. 626

Notwithstanding the growing evidence of improved drug delivery efficiency to the brain by ligand modification of PEGylated liposomes, the comprehensive knowledge of their transport processes and payload across the BBB is yet to be revealed. Herein, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6549c123859117039d65297103dcb44f
https://pubmed.ncbi.nlm.nih.gov/36055442

Microvillous tip vesicles may be an origin of placental extracellular vesicles

Autor: Rebecca Davies, Catherine Griffiths, Kathryn Askelund, Eleni Palaiologou, Jane K. Cleal, Anton Page, David S. Chatelet, Patricia Goggin, Larry Chamley, Rohan M. Lewis

Publikováno v: Placenta. 123

INTRODUCTION: Extracellular vesicles are now believed to be important mediators of placental-maternal communication. However, little is known about the formation of extracellular vesicles by human placenta. This study uses nanoscale three-dimensional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bde413c539e8fc745153fa31cac7f0c
https://pubmed.ncbi.nlm.nih.gov/35533511

A Novel Electrochemically Switchable Conductive Polymer Interface for Controlled Capture and Release of Chemical and Biological Entities

Autor: Alireza Akbarinejad, Colin Lee Hisey, Miguel Martinez‐Calderón, Jeffery Low, Devon T. Bryant, Bicheng Zhu, Diane Brewster, Eddie Wai Chi Chan, Jesna Ashraf, Ziyao Wan, Anastasiia Artuyants, Cherie Blenkiron, Larry Chamley, David Barker, David E. Williams, Clive W. Evans, Lisa I. Pilkington, Jadranka Travas‐Sejdic

Publikováno v: Advanced Materials Interfaces. 9:2102475

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2288217a318d70e41b24810d5f6e7123
https://doi.org/10.1002/admi.202102475

Immune Thrombocytopenic Purpura

Autor: Stanley M. Gartler, R. Scott Hansen, Vinzenz Oji, Heiko Traupe, Julia Horn, Bodo Grimbacher, Srijita Sen-Chowdhry, Deirdre Ward, William J. McKenna, Kar Neng Lai, Silke Hofmann, Leena Bruckner-Tuderman, Peter E. H. Schwarz, Jiang Li, Stefan Bröer, Wallace F. Marshall, Elana Lavine, Chaim M. Roifman, Makoto Miyara, Shimon Sakaguchi, Carla Rautenberg, Are Martin Holm, Marcus D. Säemann, Cord Sunderkötter, Eiji Itoi, Ursula Knirsch, Georg Gosztonyi, Valéria Lamounier-Zepter, Karen Buckingham, Larry Chamley, Alberto Ferlin, Carlo Foresta, Rudi Beyaert, Geert Loo, Egbert Mundt, Elizabeth M. Keithley, Jeffrey P. Harris, Cecilia Camacho-Hübner, Katie A. Woods, Adrian J. L. Clark, Martin O. Savage, Katie Woods, Adrian Clark, Jean-Marc Guettier, Phillip Gorden, Sumeet K. Sharma, P. Syamasundar Rao, Takeshi Uehara, Takayuki Honda, Bernd Hohenstein, Christian P. M. Hugo, Sema Uguralp, Ralf Kubitz, Dieter Häussinger, Thomas Frieling, Marcus Schmitt, Walid Ahmar, Richard W. Harper, Alexander K. C. Leung, Andrew L. Wong, Alessandra Baumer, Albert Schinzel, Orsetta Zuffardi, Roberto Ciccone, Roberto Giorda, Elio Roti, Klaus Schümann, Josef Köhrle, Günter Weiss, Matthias Wenning, Christy T. Oswalt, Christian A. Koch, Martin Schwarz, Freimut Schliess, Du Toit Loots

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b7f0fc93400ea688bd68e59dcd32875
https://doi.org/10.1007/978-3-540-29676-8_8934