Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Larry C. Cheng"'
Autor:
Larry C. Cheng, Dinghai Zheng, Erdene Baljinnyam, Fangzheng Sun, Koichi Ogami, Percy Luk Yeung, Mainul Hoque, Chi-Wei Lu, James L. Manley, Bin Tian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Alternative polyadenylation generates multiple mRNA isoforms with different 3′ UTR sizes. Here the authors report global 3′ UTR shortening that is coupled to increased expression of secretory pathway genes in secretory cell differentiation.
Externí odkaz:
https://doaj.org/article/930e44d8511440f79f4ea3c291ee5bb2
Autor:
Justin M. Drake, Leigh Ellis, Peter S. Nelson, Eva Corey, Colm Morrissey, Owen N. Witte, Ilsa Coleman, Justin H. Hwang, Rendong Yang, Jung Wook Park, John K. Lee, Ashley Petersen, Zhen Li, Victor M. Tan, Larry C. Cheng, Nathan A. Lau, Zoi Sychev, Anjali V. Sheahan, Song Yi Bae, Katherine L. Morel, Johnny R. Ramroop, Halena R. VanDeusen
Supplemental Figure 1. RET expression is higher in prostate cancer lines that have lost androgen receptor signaling Supplemental Figure 2. RET gene expression is higher in patient samples with pure/mixed small cell phenotype or primary NEPC and corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172787f33b8de3d05bd002805b2f9627
https://doi.org/10.1158/1541-7786.22516606.v1
https://doi.org/10.1158/1541-7786.22516606.v1
Autor:
Justin M. Drake, Leigh Ellis, Peter S. Nelson, Eva Corey, Colm Morrissey, Owen N. Witte, Ilsa Coleman, Justin H. Hwang, Rendong Yang, Jung Wook Park, John K. Lee, Ashley Petersen, Zhen Li, Victor M. Tan, Larry C. Cheng, Nathan A. Lau, Zoi Sychev, Anjali V. Sheahan, Song Yi Bae, Katherine L. Morel, Johnny R. Ramroop, Halena R. VanDeusen
Supplemental Table 1: Known genetic mutations of genes commonly mutated in mCRPC in cell lines used in phosphoproteome analysis Supplemental Table 2: Phospho-Serine/Threonine proteome of Prostate Cancer Adenocarcinoma and Aggressive Variant Prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214201c708af0a4efe3cdff363eced53
https://doi.org/10.1158/1541-7786.22516600
https://doi.org/10.1158/1541-7786.22516600
Autor:
Justin M. Drake, Leigh Ellis, Peter S. Nelson, Eva Corey, Colm Morrissey, Owen N. Witte, Ilsa Coleman, Justin H. Hwang, Rendong Yang, Jung Wook Park, John K. Lee, Ashley Petersen, Zhen Li, Victor M. Tan, Larry C. Cheng, Nathan A. Lau, Zoi Sychev, Anjali V. Sheahan, Song Yi Bae, Katherine L. Morel, Johnny R. Ramroop, Halena R. VanDeusen
The increased treatment of metastatic castration-resistant prostate cancer (mCRPC) with second-generation antiandrogen therapies (ADT) has coincided with a greater incidence of lethal, aggressive variant prostate cancer (AVPC) tumors that have lost d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736c0c74aacc506425582a396cd726ec
https://doi.org/10.1158/1541-7786.c.6541423
https://doi.org/10.1158/1541-7786.c.6541423
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
LNCaP GSEA analyses RNAseq data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aa3fe7b8ba133a8f4168f419a78cd5
https://doi.org/10.1158/1078-0432.22469702
https://doi.org/10.1158/1078-0432.22469702
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
Purpose: Loss of cell-cycle control is a hallmark of cancer, which can be targeted with agents, including cyclin-dependent kinase-4/6 (CDK4/6) kinase inhibitors that impinge upon the G1–S cell-cycle checkpoint via maintaining activity of the retino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420d82f5d82b3bb5856ec3ba1e79c824
https://doi.org/10.1158/1078-0432.c.6527315
https://doi.org/10.1158/1078-0432.c.6527315
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
LAPC4 phosphoproteomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c25d5fc83aa6204b5059dc505b86e7
https://doi.org/10.1158/1078-0432.22469693.v1
https://doi.org/10.1158/1078-0432.22469693.v1
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
Cbioportal analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cada900637d591b15ced848ab4c65b7
https://doi.org/10.1158/1078-0432.22469684.v1
https://doi.org/10.1158/1078-0432.22469684.v1
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
LAPC4 aggressive phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a66cad085a66ac30531c24ebd7baa9
https://doi.org/10.1158/1078-0432.22469690.v1
https://doi.org/10.1158/1078-0432.22469690.v1
Autor:
Karen E. Knudsen, Wm. Kevin Kelly, Justin M. Drake, J. Alan Diehl, Maha H. Hussain, Gary Hardiman, E. Starr Hazard, Sean M. Courtney, Akihiro Yoshida, Larry C. Cheng, Zhen Li, Michael A. Augello, Lucas J. Brand, Neermala Poudel Neupane, Matthew J. Schiewer, Christopher McNair, Renée de Leeuw
LAPC4 GSEA analyses RNAseq data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddb45a4c270b767233f678fb81d6c88
https://doi.org/10.1158/1078-0432.22469696
https://doi.org/10.1158/1078-0432.22469696