Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Larry C Lasky"'
Autor:
Li Chen, Rulong Shen, Yin Ye, Xin-An Pu, Xingluo Liu, Wenrui Duan, Jing Wen, Jason Zimmerer, Ying Wang, Yan Liu, Larry C Lasky, Nyla A Heerema, Danilo Perrotti, Keiko Ozato, Satomi Kuramochi-Miyagawa, Toru Nakano, Allen J Yates, William E Carson, Haifan Lin, Sanford H Barsky, Jian-Xin Gao
Publikováno v:
PLoS ONE, Vol 2, Iss 3, p e293 (2007)
Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors-namely, precancerous stem cells (pCSCs) -have not been characterized. Here we experimentally define the pCSCs that have the potential for both
Externí odkaz:
https://doaj.org/article/8b5da628b41d4856a65eb753f812b138
Publikováno v:
Biochemical and Biophysical Research Communications. 398:377-382
In order to ex vivo produce clinically useful quantity of platelets, we may need to firstly enhance early self-renewal of hematopoietic stem cells (HSCs) and/or megakaryocyte (Mk) progenitors. The homeodomain transcription factor HoxB4 has been shown
Autor:
Armin Schubert, Andrew C. Novick, Michael E. Saunders, Edward J. Mascha, Robert J. Przybelski, John F. Eidt, Kenneth E. Marks, John E. Tetzlaff, Larry C. Lasky, John W. Blue, Jerome F. O'Hara, Matthew Karafa
Publikováno v:
Anesthesia & Analgesia. 97:323-332
§§Departments of *General Anesthesiology, †Department of Orthopedic Surgery, ‡Department of Urology, §Department ofBiostatistics & Epidemiology, The Cleveland Clinic Foundation; Cleveland Clinic Foundation Health Science Center of theOhio Stat
Publikováno v:
Cytotechnology. 41:23-35
Embryonic stem (ES) cells have indefinite self-renewal ability and pluripotency, and can provide a novel cell source for tissue engineering applications. In this study, a murine CCE ES cell line was used to derive hematopoietic cells in a 3-D fibrous
Autor:
Larry C. Lasky, Lee R. Moore, Maciej Zborowski, E. Julia Chosy, Kristin Comella, Kristie Melnik, Keith F. Decker, Masayuki Nakamura, Jeffrey J. Chalmers
Publikováno v:
Biotechnology Progress. 17:1145-1155
We have developed a quadrupole magnetic flow sorter (QMS) to facilitate high-throughput binary cell separation. Optimized QMS operation requires the adjustment of three flow parameters based on the immunomagnetic characteristics of the target cell sa
Publikováno v:
Journal of Hematotherapy & Stem Cell Research. 10:355-368
Current hematopoietic culture systems mainly utilize two-dimensional devices with limited ability to promote self-renewal of early progenitors. In vivo-like three-dimensional (3-D) culture environments might be conducive to regulating stem cell proli
Publikováno v:
Experiments in Fluids. 30:371-380
A theoretical and experimental analysis has been conducted to determine the accuracy of cell tracking velocimetry (CTV). CTV is an analytical technique for quantifying magnetically induced velocity of immunomagnetically labeled cells (or particles),
Autor:
Timothy E. Gorman, A. Ng, Carmen J. Julius, James N. Allen, Rolf F. Barth, Melanie S. Kennedy, Thomas W. Prior, Larry C. Lasky
Publikováno v:
American Journal of Clinical Pathology. 113:732-737
Transfusion-associated graft-vs-host disease (TA-GVHD) is a rare complication of transfusion. We report fatal TA-GVHD in a 63-year-old coronary artery bypass patient of European descent after an RBC transfusion from an unrelated donor. The patient ha
Autor:
Jeffrey J. Chalmers, Masayuki Nakamura, Yang Zhao, Lee R. Moore, Kristie Melnik, Larry C. Lasky, Maciej Zborowski
Publikováno v:
Journal of Magnetism and Magnetic Materials. 194:231-241
An instrument is described and discussed which can determine the magnetophoretic mobility of immunomagnetically labeled cells and paramagnetic particles. Through the use of a well-characterized magnetic energy gradient and a computer algorithm, cell
Autor:
Larry C. Lasky, Brent Sullenbarger
Publikováno v:
Tissue engineering. Part C, Methods. 17(11)
A method to produce clinically useful platelets in vitro would help overcome the frequent shortages, donor deferrals, disease transmission, and alloimmunization with volunteer donor-derived platelets. Using CD34 positively selected cord blood cells,