Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Larry C Ackerson"'
Autor:
Rafael Romero-Calderón, Guido Uhlenbrock, Jolanta Borycz, Anne F Simon, Anna Grygoruk, Susan K Yee, Amy Shyer, Larry C Ackerson, Nigel T Maidment, Ian A Meinertzhagen, Bernhard T Hovemann, David E Krantz
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000245 (2008)
Unlike other monoamine neurotransmitters, the mechanism by which the brain's histamine content is regulated remains unclear. In mammals, vesicular monoamine transporters (VMATs) are expressed exclusively in neurons and mediate the storage of histamin
Externí odkaz:
https://doaj.org/article/0a5c04b346044691ac0fa50256b893da
Autor:
Farzad Mortazavi, Nigel T. Maidment, Linda Tsan, Franziska Richter, Caitlyn K. Mulligan, Lauryn Gabby, Pedrom C. Sioshansi, Larry C. Ackerson, Krystal De La Rosa, Marie-Françoise Chesselet, Ingrid C. Cely, Niall P. Murphy, Kimberly A. McDowell
Publikováno v:
Neurobiology of Aging. 51:54-66
How genetic variations in the dopamine transporter (DAT) combined with exposure to environmental toxins modulate the risk of Parkinson's disease remains unclear. Using unbiased stereology in DAT knock-down mice (DAT-KD) and wild-type (WT) littermates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95bff011fe21c7af1bb0a43cdd72307
https://doi.org/10.1016/j.neurobiolaging.2016.11.015
https://doi.org/10.1016/j.neurobiolaging.2016.11.015
Autor:
Bernhard H. Meurers, Xiao-Hong Lu, Farzad Mortazavi, X. William Yang, Victor Lo, Larry C. Ackerson, Nigel T. Maidment, Marie-Françoise Chesselet, Sheila M. Fleming, George R. Jackson, David Sulzer, Daniela Hernandez
Publikováno v:
The Journal of Neuroscience. 29:1962-1976
Recessive mutations in parkin are the most common cause of familial early-onset Parkinson's disease (PD). Recent studies suggest that certain parkin mutants may exert dominant toxic effects to cultured cells and such dominant toxicity can lead to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5356a49b61ea9121d6e59d4f67c84ac
https://doi.org/10.1523/jneurosci.5351-08.2009
https://doi.org/10.1523/jneurosci.5351-08.2009
Autor:
Mordecai Solomon, Richard W. Daniels, David Shamouelian, Nigel T. Maidment, Anna Grygoruk, Rafael Romero-Calderón, Aaron DiAntonio, Evelyn D. Salazar, Anne Simon, Hui-Yun Chang, Larry C. Ackerson, David E. Krantz, Rod Najibi
Publikováno v:
Genetics. 181:525-541
Physiologic and pathogenic changes in amine release induce dramatic behavioral changes, but the underlying cellular mechanisms remain unclear. To investigate these adaptive processes, we have characterized mutations in the Drosophila vesicular monoam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8dccc20e271c99050c7261df25d4b1
https://doi.org/10.1534/genetics.108.094110
https://doi.org/10.1534/genetics.108.094110
Publikováno v:
European Journal of Neuroscience. 23:151-160
It has been suggested that Group I metabotropic glutamate receptor antagonists could have potential therapeutic value in the treatment of Parkinson's disease. There is evidence that when given systemically, 2-methyl-6-(phenylethynyl)-pyridine (MPEP),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f318838cdbe0d7038497e38383087fc0
https://doi.org/10.1111/j.1460-9568.2005.04550.x
https://doi.org/10.1111/j.1460-9568.2005.04550.x
Autor:
Larry C. Ackerson, Sara M. West, Adriana Galván, Thomas Wichmann, Rosa M. Villalba, Yoland Smith, Nigel T. Maidment
Publikováno v:
Journal of Neurophysiology. 94:990-1000
Neurons in the external and internal segment of the globus pallidus (GPe and GPi, respectively) receive substantial GABAergic inputs from the striatum and through axon collaterals of neighboring pallidal neurons. The effects of GABA on pallidal activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d54d429d6fb9c1bf18323390b9d3fab
https://doi.org/10.1152/jn.00068.2005
https://doi.org/10.1152/jn.00068.2005
Autor:
Tony A. Fields, Jerome Engel, Charles L. Wilson, Larry C. Ackerson, Nigel T. Maidment, Jack W. Morrow, Itzhak Fried, Eric Behnke, Katherine A. Macdonald
Publikováno v:
Journal of Neurosurgery. 91:697-705
✓ Monitoring physiological changes in the brain parenchyma has important applications in the care of neurosurgical patients. A technique is described for measuring extracellular neurochemicals by cerebral microdialysis with simultaneous recording o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc6b7435d4d782e5dbbd2ac7757724f
https://doi.org/10.3171/jns.1999.91.4.0697
https://doi.org/10.3171/jns.1999.91.4.0697
Autor:
Rachel L Kelly, Audrey Chen, F. Rob Jackson, Rod Najibi, Tim Lebestky, Filmon Mehanzel, Gabriel Seidman, David E. Krantz, Harshul A. Zaveri, Niall P. Murphy, Nigel T. Maidment, Christine Djapri, Fanny S. Ng, Hakeem O. Lawal, Larry C. Ackerson, Anna Grygoruk
To investigate the regulation of Drosophila melanogaster behavior by biogenic amines, we have exploited the broad requirement of the vesicular monoamine transporter (VMAT) for the vesicular storage and exocytotic release of all monoamine neurotransmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a08b04eba631fb12d3abd6ed44dc4b
https://europepmc.org/articles/PMC3527243/
https://europepmc.org/articles/PMC3527243/
Autor:
Larry C. Ackerson, Hao Fei, Julie H. Simpson, Wei S. Ong, Nigel T. Maidment, Rafael Romero-Calderón, Dawnis M. Chow, Audrey Chen, Mark A. Frye, David E. Krantz
Publikováno v:
The Journal of experimental biology. 213(Pt 10)
SUMMARYThe role of gamma amino butyric acid (GABA) release and inhibitory neurotransmission in regulating most behaviors remains unclear. The vesicular GABA transporter (VGAT) is required for the storage of GABA in synaptic vesicles and provides a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e34443c95cc7d4d0f22edde5a00c31
https://pubmed.ncbi.nlm.nih.gov/20435823
https://pubmed.ncbi.nlm.nih.gov/20435823
Autor:
Guido Uhlenbrock, Anna Grygoruk, Amy Shyer, Nigel T. Maidment, Bernhard T. Hovemann, Ian A. Meinertzhagen, Larry C. Ackerson, Susan K. Yee, Anne Simon, Jolanta A. Borycz, Rafael Romero-Calderón, David E. Krantz
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000245 (2008)
PLoS Genetics
PLoS genetics, vol 4, iss 11
PLoS Genetics
PLoS genetics, vol 4, iss 11
Unlike other monoamine neurotransmitters, the mechanism by which the brain's histamine content is regulated remains unclear. In mammals, vesicular monoamine transporters (VMATs) are expressed exclusively in neurons and mediate the storage of histamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87458450e9ea173e30895442a078d6e5
http://europepmc.org/articles/PMC2570955?pdf=render
http://europepmc.org/articles/PMC2570955?pdf=render