Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Larry Boyle"'
Autor:
John Kunich, Serah Choi, Kusum Pandey, Larry Boyle, Bridget Bagus, Yuqiao Shen, Gaston Habets, Frank McCormick, Conrado Soria, Dave Ginzinger, Annie Shen, Clodagh C. O’Shea, Cory R. Nicholas, Leisa Johnson
Publikováno v:
Cancer Cell. 6(6):611-623
ONYX-015 is an adenovirus that lacks the E1B-55K gene product for p53 degradation. Thus, ONYX-015 was conceived as an oncolytic virus that would selectively replicate in p53-defective tumor cells. Here we show that loss of E1B-55K leads to the induct
Autor:
Larry Boyle, Leisa Johnson, Frank McCormick, Annie Shen, John Kunich, Ali Fattaey, Terry Hermiston, Marilyn Lemmon, Marty Giedlin, Kusum Pandey
Publikováno v:
Cancer Cell. 1:325-337
We have engineered a human adenovirus, ONYX-411, that selectively replicates in human tumor cells, but not normal cells, depending upon the status of their retinoblastoma tumor suppressor protein (pRB) pathway. Early and late viral gene expression as
Autor:
Herbert Breslert, Larry Boyle, Farshid Oshidari, Lee Ann Feeney, Dewey J. Moody, Beth Vertin, Sohel Talib
Publikováno v:
Journal of Immunotherapy. 16:235
Autor:
Larry Boyle
Publikováno v:
American Political Science Review. 79:847-848