Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Larry, Blankstein"'
Autor:
Aoife M. Brennan, Larry Blankstein, Mark R. Charbonneau, Mary Castillo, John A. Phillips, Benjamin D. Goodlett, William S. Denney, Caroline B. Kurtz, David A. Wagner, Jerry Vockley, Marja K. Puurunen, Stephanie Sacharow, Vincent M. Isabella, Vasu V. Sethuraman, Richard Riese, Shawn Searle
Publikováno v:
Nature Metabolism. 3:1125-1132
Phenylketonuria (PKU) is a rare disease caused by biallelic mutations in the PAH gene that result in an inability to convert phenylalanine (Phe) to tyrosine, elevated blood Phe levels and severe neurological complications if untreated. Most patients
Autor:
Marja K. Puurunen, Jerry Vockley, Shawn L. Searle, Stephanie J. Sacharow, John A. Phillips, William S. Denney, Benjamin D. Goodlett, David A. Wagner, Larry Blankstein, Mary J. Castillo, Mark R. Charbonneau, Vincent M. Isabella, Vasu V. Sethuraman, Richard J. Riese, Caroline B. Kurtz, Aoife M. Brennan
Publikováno v:
Nature Metabolism. 4:1214-1214
Autor:
Marja K, Puurunen, Jerry, Vockley, Shawn L, Searle, Stephanie J, Sacharow, John A, Phillips, William S, Denney, Benjamin D, Goodlett, David A, Wagner, Larry, Blankstein, Mary J, Castillo, Mark R, Charbonneau, Vincent M, Isabella, Vasu V, Sethuraman, Richard J, Riese, Caroline B, Kurtz, Aoife M, Brennan
Publikováno v:
Nature metabolism. 3(8)
Phenylketonuria (PKU) is a rare disease caused by biallelic mutations in the PAH gene that result in an inability to convert phenylalanine (Phe) to tyrosine, elevated blood Phe levels and severe neurological complications if untreated. Most patients
Autor:
Paul Miller, Larry Blankstein, Saurabh Saha, Jonathan W. Kotula, Caroline B. Kurtz, William S. Denney, Sarah E. Guilmain, Aoife M. Brennan, Suman Machinani
Publikováno v:
Clinical and Translational Science. 11:200-207
Understanding the pharmacology of microbiome-based therapeutics is required to support the development of new medicines. Strains of E. coli Nissle (EcN) were genetically modified and administered to cynomolgus monkeys at doses of 1 × 109 and 1 × 10
Autor:
Caroline B. Kurtz, William S. Denney, Larry Blankstein, Richard Riese, Shawn Searle, Aoife M. Brennan, Marja K. Puurunen
Publikováno v:
Molecular Genetics and Metabolism. 132:S105-S106
Autor:
Larry Blankstein, Aoife M. Brennan, Cami Anderson, William S. Denney, William M. Lee, Raymond T. Chung, Marielys Padilla-Martinez, Marja K. Puurunen, Patricia P. Bloom, Tarek Hassanein, Edith Gavis, Don C. Rockey, Zeid Kayali, Roula Sasso, Jasmohan S. Bajaj, Eric Lawitz, Alagar Muthukumar
Publikováno v:
The American journal of gastroenterology. 115(5)
INTRODUCTION Ammonia levels are used to assess hepatic encephalopathy, but their levels are highly variable in clinical practice. METHODS We studied factors associated with variation in ammonia values in cirrhotic patients without previous hepatic en
Autor:
Ana Cristina Puga, David Mathews, William G. Kramer, Peter L. Bonate, Amy Burke, M. Judith Peterschmitt, Sharon E. Smith, James A. Harris, Larry Blankstein
Publikováno v:
The Journal of Clinical Pharmacology. 51:695-705
Three phase 1 studies of eliglustat tartrate (Genz-112638), an oral inhibitor of glucosylceramide synthase under development for treating Gaucher disease type 1 (GD1), evaluated the safety, tolerability, and pharmacokinetics in healthy volunteers aft
Autor:
Larry Blankstein, William S. Denney, Caroline B. Kurtz, Aoife M. Brennan, R. Goldwater, T. Parsons, Marja K. Puurunen, Yves Millet
Publikováno v:
Journal of Hepatology. 68:S737
Autor:
Neal J. Weinreb, Larry Blankstein, Daniel Gruskin, Gustavo Maegawa, Michael J. Gambello, Ozlem Goker-Alpan, Khan Nedd
Publikováno v:
JIMD Reports ISBN: 9783662496671
Agalsidase alfa and agalsidase beta, recombinant enzyme preparations for treatment of Fabry disease (FD), have different approved dosing schedules: 0.2 mg/kg and 1.0 mg/kg every other week (EOW), respectively.This open-label, multicenter, exploratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aa28a3a5323ceca6e32815321f494c
https://europepmc.org/articles/PMC5059194/
https://europepmc.org/articles/PMC5059194/
Autor:
Michael J. Gambello, Neal J. Weinreb, Larry Blankstein, Gustavo Maegawa, Daniel Gruskin, Ozlem Goker-Alpan, Khan Nedd, John A. Barranger
Publikováno v:
Molecular Genetics and Metabolism. 111:S24