A Nuclear Magnetic Resonance (NMR)- and Mass Spectrometry (MS)-Based Saturation Kinetics Model of a Bryophyllum pinnatum Decoction as a Treatment for Kidney Stones.

Autor: Chik C; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada., Larroque AL; The Research Institute of the McGill University Health Center, Montreal, QC H4A 3J1, Canada., Zhuang Y; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada., Feinstein S; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada., Smith DL; Plant Science Department, McDonald Campus, McGill University, Sainte-Anne-de-Bellevue, QC H9X 3V9, Canada., Andonian S; The Research Institute of the McGill University Health Center, Montreal, QC H4A 3J1, Canada.; Division of Urology, McGill University, Montreal, QC H4A 3J1, Canada., Ryan AK; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.; The Research Institute of the McGill University Health Center, Montreal, QC H4A 3J1, Canada.; Department of Pediatrics, McGill University, Montreal, QC H4A 3J1, Canada., Jean-Claude B; The Research Institute of the McGill University Health Center, Montreal, QC H4A 3J1, Canada.; Department of Medicine, Division of Medical Oncology, McGill University, Montreal, QC H4A 3J1, Canada., Gupta IR; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.; The Research Institute of the McGill University Health Center, Montreal, QC H4A 3J1, Canada.; Department of Pediatrics, McGill University, Montreal, QC H4A 3J1, Canada.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 May 12; Vol. 25 (10). Date of Electronic Publication: 2024 May 12.

Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model.

Autor: Facchin C; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Fraga-Timiraos AB; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Schmitt J; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Babaa N; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Pannu N; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Aliaga A; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Larroque AL; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada., Jean-Claude BJ; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.

Publikováno v: Cells [Cells] 2023 Mar 16; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 16.

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Molecular analysis of the in vivo metabolism and biodistribution of metabolically and non-metabolically activated combi-molecules of the triazene class.

Autor: Qiu Q; Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, McGill University/Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, Canada., Larroque AL, Gibbs B, Fang Y, Lakhrissi Y, Soucy JP, Mzengeza S, Rachid Z, Jean-Claude BJ

Publikováno v: Drug metabolism letters [Drug Metab Lett] 2009 Jan; Vol. 3 (1), pp. 1-9.

Optimization of novel combi-molecules: identification of balanced and mixed bcr-abl/DNA targeting properties.

Autor: Rachid Z; Cancer Drug Research Laboratory, Division of Medical Oncology, Department of Medicine, McGill University/Royal Victoria Hospital, 687 Pine Avenue West Rm. M-719, Montreal, Que., Canada H3A 1A1., Katsoulas A, Williams C, Larroque AL, McNamee J, Jean-Claude BJ

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Aug 01; Vol. 17 (15), pp. 4248-53. Date of Electronic Publication: 2007 May 24.