High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon

Autor: Anne C. G. Almeida, Andrea Kuehn, Arthur J. M. Castro, Sheila Vitor-Silva, Erick F. G. Figueiredo, Larissa W. Brasil, Marcelo A. M. Brito, Vanderson S. Sampaio, Quique Bassat, Ingrid Felger, Wanderli P. Tadei, Wuelton M. Monteiro, Ivo Mueller, Marcus V. G. Lacerda

Publikováno v: Parasites & Vectors, Vol 11, Iss 1, Pp 1-13 (2018)

Abstract Background Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts aiming at regional elimination, it is important to investigate the role o

Externí odkaz: https://doaj.org/article/b4203de98f7a4f02abf9677e4b8a6345

Impact of Plasmodium vivax malaria and antimalarial treatment on cytochrome P450 activity in Brazilian patients

Autor: Guilherme Suarez-Kurtz, Erick F. G. Figueiredo, Anna Beatriz Ribeiro Elias, Larissa W. Brasil, Fernanda Rodrigues-Soares, Maria Paula Marques, Allyson Guimarães Costa, Wuelton Marcelo Monteiro, Gisely Cardoso de Melo, Anne Cristine Gomes de Almeida, Vera Lucia Lanchote, Marcus V. G. Lacerda

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

AIMS To investigate the impact of Plasmodium vivax malaria and chloroquine-primaquine chemotherapy on CYP2D6 and CYP2C19 activity in patients from the Brazilian Amazon. METHODS Adult patients (n = 30) were given subtherapeutic doses of CYP2D6 and CYP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07a16c73dc405b74ea5151553eef0cc
https://pubmed.ncbi.nlm.nih.gov/32997351

High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon

Autor: Andrea Kuehn, Arthur J. M. Castro, Vanderson de Souza Sampaio, Ivo Mueller, Anne Cristine Gomes de Almeida, Ingrid Felger, Sheila Vitor-Silva, Erick F. G. Figueiredo, Wanderli Pedro Tadei, Marcelo A M Brito, Wuelton Marcelo Monteiro, Larissa W. Brasil, Quique Bassat, Marcus V. G. Lacerda

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Repositório Institucional do INPA
Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
Recercat. Dipósit de la Recerca de Catalunya
instname
Parasites & Vectors, Vol 11, Iss 1, Pp 1-13 (2018)
Parasites & Vectors

BACKGROUND: Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts aiming at regional elimination, it is important to investigate the role of this a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4821e1682d29905c64e259ef1ead6ed
http://hdl.handle.net/2445/121305

Plasmodium vivax Chloroquine Resistance and Anemia in the Western Brazilian Amazon

Autor: Fátima Nogueira, Wuelton Marcelo Monteiro, Monica R. F. Costa, Roberto C Reyes-Lecca, Franklin Simões de Santana Filho, Maria das Graças Costa Alecrim, Henrique Silveira, Larissa W. Brasil, Marcus V. G. Lacerda, Margareth Tavares Silva Nascimento, Marly M. Marques, José Luiz Fernandes Vieira

Publikováno v: Antimicrobial Agents and Chemotherapy. 58:342-347

Data on chloroquine (CQ)-resistant Plasmodium vivax in Latin America is limited, even with the current research efforts to sustain an efficient malaria control program in all these countries where P. vivax is endemic and where malaria still is a majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d235445823fbe407e3c780d9f82a810
https://doi.org/10.1128/aac.02279-12

TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon

Autor: Wuelton Marcelo Monteiro, Marcus V. G. Lacerda, Andrea Kuhn, Larissa W. Brasil, Felipe Jules de Araújo, Luan Diego Oliveira da Silva, Laila R. A. Barbosa, Allyson Guimarães Costa, Sheila Vitor-Silva, Rajendranath Ramasawmy, Suzana Kanawati Pinheiro, Gisely Cardoso de Melo, Anne Cristine Gomes de Almeida

Publikováno v: Malaria Journal

Background Toll-interacting protein is a negative regulator in the TLR signaling cascade, particularly by impeding the TLR2 and, TLR4 pathway. Recently, TOLLIP was shown to regulate human TLR signaling pathways. Two common TOLLIP polymorphisms (rs574

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fd15a7e8a8fef2cd594f60f70bdc50