Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Larissa Nassauer"'
Autor:
Larissa Nassauer, Hinrich Staecker, Peixin Huang, Bryan Renslo, Madeleine Goblet, Jennifer Harre, Athanasia Warnecke, Juliane W. Schott, Michael Morgan, Melanie Galla, Axel Schambach
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102157- (2024)
Cisplatin is a highly effective chemotherapeutic agent, but it can cause sensorineural hearing loss (SNHL) in patients. Cisplatin-induced ototoxicity is closely related to the accumulation of reactive oxygen species (ROS) and subsequent death of hair
Externí odkaz:
https://doaj.org/article/fa09f49038244138abbce7ed6e21d4c8
Autor:
Yvonne Baron, Johanna Sens, Lucas Lange, Larissa Nassauer, Denise Klatt, Dirk Hoffmann, Marc-Jens Kleppa, Philippe Vollmer Barbosa, Maximilian Keisker, Viviane Steinberg, Julia D. Suerth, Florian W.R. Vondran, Johann Meyer, Michael Morgan, Axel Schambach, Melanie Galla
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 810-823 (2022)
DNA-modifying technologies, such as the CRISPR-Cas9 system, are promising tools in the field of gene and cell therapies. However, high and prolonged expression of DNA-modifying enzymes may cause cytotoxic and genotoxic side effects and is therefore u
Externí odkaz:
https://doaj.org/article/7d3c9c912d7a421e93b440a7eebf070a