Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Larissa Magalhães Alvarenga"'
Autor:
Lara Maria Kalempa Demeu, Rodrigo Jahn Soares, Juliana Severo Miranda, Lisandro A Pacheco-Lugo, Kelin Gonçalves Oliveira, Cristian Andrés Cortez Plaza, Philippe Billiald, Juliana Ferreira de Moura, Nobuko Yoshida, Larissa Magalhães Alvarenga, Wanderson Duarte DaRocha
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223773 (2019)
Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs available is limited to the acute phase. Therefore, there is an unmet need for innovative
Externí odkaz:
https://doaj.org/article/f2d994cfc7cd4b4583e4169afee97c6a
Autor:
Juliana Reis Burjack, Arquimedes Paixão Santana-Filho, Andrea Caroline Ruthes, Daniel Suss Riter, Vania Aparecida Vicente, Larissa Magalhães Alvarenga, Guilherme Lanzi Sassaki
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Dematiaceous fungi constitute a large and heterogeneous group, characterized by having a dark pigment, the dihydroxynaftalen melanin - DHN, inside their cell walls. In nature they are found mainly as soil microbiota or decomposing organic matter, and
Externí odkaz:
https://doaj.org/article/1158c6e91b634cc6aafbcef3a350f270
Autor:
Silvana Maria Alban, Juliana Ferreira de Moura, Vanete Thomaz-Soccol, Samira Bührer Sékula, Larissa Magalhães Alvarenga, Marcelo Távora Mira, Carlos Chávez Olortegui, João Carlos Minozzo
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106222 (2014)
The diagnosis of leprosy is primarily based on clinical manifestations, and there is no widely available laboratory test for the early detection of this disease, which is caused by Mycobacterium leprae. In fact, early detection and treatment are the
Externí odkaz:
https://doaj.org/article/dd336f78bcd0470abd82888685046d29
Autor:
Isabella Gizzi Jiacomini, Martina Beltramino, Fanny Boursin, João Carlos Minozzo, Juliana Ferreira de Moura, Philippe Billiald, Larissa Magalhães Alvarenga, Nicolas Aubrey
Publikováno v:
International journal of biological macromolecules. 216
The use of monoclonal antibodies (mAbs) in therapy is gradually advancing and discussions entail its safety, rentability and effectiveness. To this date, around a hundred mAbs have been approved by the FDA for the treatment of various diseases. Aimin
Autor:
Vanete Thomaz Soccol, Luis Felipe M. Figueiredo, Ricardo Andrez Machado-de-Ávila, Sabrina de Almeida Lima, Silvio Sanches Veiga, Thamyres C. Silva de Assis, Clara Guerra-Duarte, Christina A. Martins, Carlos Chávez-Olórtegui, Tamara G.F. Costa, Larissa Magalhães Alvarenga, Evanguedes Kalapothakis, Alessandra Becker Finco, João Carlos Minozzo, Fernanda Costal-Oliveira
Publikováno v:
International Journal of Biological Macromolecules. 162:490-500
Loxoscelism pose a health issue in the South America. The treatment for these accidents is based on the administration of antivenom produced in animals immunized with Loxosceles venom. In this work, a previously produced non-toxic multiepitopic chime
Autor:
Philippe Billilad, Bianca Prado-Costa, Alessandra Becker-Finco, Larissa Magalhães Alvarenga, Juliana de Moura, Cinthia Furst, Adriana Oliveira Costa, Michele Martha Weber-Lima
Publikováno v:
Parasitology
Free-living amoeba of the genus Acanthamoeba are ubiquitous protozoa involved in opportunistic and non-opportunistic infection in humans, such as granulomatous amoebic encephalitis and amoebic keratitis. Both infections have challenging characteristi
Autor:
Larissa Magalhães Alvarenga, Bonald C. Figueiredo, Kádima Nayara Teixeira, Juliana de Moura, Lucia de Noronha, Rosana Nogueira Moraes, Philippe Billiald, Rafaela Lenzi Fogaça, Magali Noiray, Thiago Demetrius Woiski, Alessandra Becker-Finco, Sabrina Karim Silva
Publikováno v:
Nanomedicine. 14:689-705
Aim: To develop a monoclonal antibody against dehydroepiandrosterone (DHEA) and miniaturize it, generating a single-chain antibody variable fragment (scFv) against DHEA as an adrenocortical carcinoma (ACC) marker. Material & methods: DHEA conjugated
Autor:
Marcel I. Ramirez, Larissa Magalhães Alvarenga, Isabella Gizzi Jiacomini, Guillermo Andrés Cerquera Cardenas
Publikováno v:
Toxicology letters. 350
Envenomation by the Loxosceles genus spiders is a recurring health issue worldwide and specially in the Americas. The physiopathology of the envenomation is tightly associated to the venom's rich toxin composition, able to produce a local dermonecrot
Autor:
Cristiane Zocatelli-Ribeiro, Ricardo Andrez Machado-de-Ávila, Juliana de Moura, João Paulo Stanke Scandelari, Juliana Ferreira de Santana, Bruno Araujo Soares, Larissa Magalhães Alvarenga, Bianca Luiza Melo de Assis, Kádima Nayara Teixeira, Vanete Thomaz-Soccol
Publikováno v:
Molecular immunology. 138
Knowledge of immunodominant B-cell epitopes is essential to design powerful diagnostic strategies aiming for antibody detection. Outstanding progress in computational prediction has achieved a significant contribution to the biomedical fields, includ
Autor:
Isabel B. Yamanaka, Rilton Alves de Freitas, Carla Yoko Tanikawa de Andrade, Sabrina Karim Silva, Juliana de Moura, Guilherme Fadel Picheth, Laís S. Schlichta, Larissa Magalhães Alvarenga, Luiz Felipe Caron
Publikováno v:
Carbohydrate Polymers. 185:63-72
To propose a novel modeling of aflatoxin immunization and surrogate toxin conjugate from AFB1 vaccines, an immunogen based on the mimotope, (i.e. a peptide-displayed phage that mimics aflatoxins epitope without toxin hazards) was designed. The recomb