Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Larissa Hering"'
Autor:
Gerhard Rogler, Arndt Hartmann, Marianne Rebecca Spalinger, Michael Scharl, Elisabeth Naschberger, Jesus Francisco Glaus Garzon, Silvia Lang, Kirstin Atrott, Philipp Busenhart, Ana Montalban-Arques, Egle Katkeviciute, Yasser Morsy, Chiara Van Passen, Larissa Hering, Michael Stürzl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/19040f65b7694fdf88048f127a56fc97
Autor:
Larissa Hering, Egle Katkeviciute, Marlene Schwarzfischer, Philipp Busenhart, Claudia Gottier, Dunja Mrdjen, Juliana Komuczki, Marcin Wawrzyniak, Silvia Lang, Kirstin Atrott, Burkhard Becher, Gerhard Rogler, Michael Scharl, Marianne R. Spalinger
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Protein tyrosine phosphatase non-receptor type 2 (PTPN2) plays a pivotal role in immune homeostasis and has been associated with human autoimmune and chronic inflammatory diseases. Though PTPN2 is well-characterized in lymphocytes, little is known ab
Externí odkaz:
https://doaj.org/article/cbebd70e616b461caf11840570e37a9a
Autor:
Marianne R. Spalinger, Roberto Manzini, Larissa Hering, Julianne B. Riggs, Claudia Gottier, Silvia Lang, Kirstin Atrott, Antonia Fettelschoss, Florian Olomski, Thomas M. Kündig, Michael Fried, Declan F. McCole, Gerhard Rogler, Michael Scharl
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1835-1848 (2018)
Summary: Variants in the gene locus encoding protein tyrosine phosphatase non-receptor type 2 (PTPN2) are associated with inflammatory disorders, including inflammatory bowel diseases, rheumatoid arthritis, and type 1 diabetes. The anti-inflammatory
Externí odkaz:
https://doaj.org/article/ca112df31c744a088f3ad91228a70e72
Autor:
Larissa Hering, Egle Katkeviciute, Marlene Schwarzfischer, Anna Niechcial, Julianne B. Riggs, Marcin Wawrzyniak, Kirstin Atrott, Marnix van de Sande, Silvia Lang, Burkhard Becher, Gerhard Rogler, Michael Scharl, Marianne R. Spalinger
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6820 (2021)
Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) plays a critical role in the pathogenesis of inflammatory bowel diseases (IBD). Mice lacking PTPN2 in dendritic cells (DCs) develop skin and liver inflammation by the age of 22 weeks due to a ge
Externí odkaz:
https://doaj.org/article/87684b289e354c539e20a9e5c94c2d05
Autor:
Marlene Schwarzfischer, Anna Niechcial, Kristina Handler, Yasser Morsy, Marcin Wawrzyniak, Andrea S Laimbacher, Kirstin Atrott, Roberto Manzini, Katharina Baebler, Larissa Hering, Egle Katkeviciutė, Janine Häfliger, Silvia Lang, Maja E Keller, Jérôme Woodtli, Lisa Eisenbeiss, Thomas Kraemer, Elisabeth M Schraner, Mahesa Wiesendanger, Sebastian Zeissig, Gerhard Rogler, Andreas E Moor, Michael Scharl, Marianne R Spalinger
Publikováno v:
Gut. 72:1101-1114
ObjectiveInflammatory bowel disease (IBD) is a multifactorial condition driven by genetic and environmental risk factors. A genetic variation in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene has been associated with autoimmune d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82a3a498d670663c1e786d0ad3ad136
https://doi.org/10.1136/gutjnl-2021-325911
https://doi.org/10.1136/gutjnl-2021-325911
Autor:
Jesus Cosin-Roger, Gerhard Rogler, Pedro A. Ruiz, Hassan Melhem, Katharina Baebler, Chiaki Maeyashiki, Bruce Weder, Cheryl de Valliere, Michael Scharl, Larissa Hering, Fabian Schefer, Martin Hausmann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Proton-sensing ovarian cancer G-protein coupled receptor (OGR1) plays an important role in pH homeostasis. Acidosis occurs at sites of intestinal inflammation and can induce endoplasmic reticulum (ER) stress and the unfolded protein response (UPR), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33af7a5f0c9484f192d933662e099d8
http://link.springer.com/article/10.1038/s41598-020-57657-9
http://link.springer.com/article/10.1038/s41598-020-57657-9
Autor:
Marlene, Schwarzfischer, Anna, Niechcial, Kristina, Handler, Yasser, Morsy, Marcin, Wawrzyniak, Andrea S, Laimbacher, Kirstin, Atrott, Roberto, Manzini, Katharina, Baebler, Larissa, Hering, Egle, Katkeviciutė, Janine, Häfliger, Silvia, Lang, Maja E, Keller, Jérôme, Woodtli, Lisa, Eisenbeiss, Thomas, Kraemer, Elisabeth M, Schraner, Mahesa, Wiesendanger, Sebastian, Zeissig, Gerhard, Rogler, Andreas E, Moor, Michael, Scharl, Marianne R, Spalinger
Publikováno v:
Gut.
Inflammatory bowel disease (IBD) is a multifactorial condition driven by genetic and environmental risk factors. A genetic variation in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene has been associated with autoimmune disorders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::262654e5ca5d21c4972015ff59a71543
https://pubmed.ncbi.nlm.nih.gov/36191962
https://pubmed.ncbi.nlm.nih.gov/36191962
Autor:
Alina N. Santos, Ali Shawki, Gerhard Rogler, Marlene Schwarzfischer, Gabriel E. Leventhal, Silvia Lang, Christophe Lacroix, Anica Sayoc, Marianne R. Spalinger, Larissa Hering, Katharina Bäbler, David J. Rawlings, Claudia Gottier, Andrew A Chan, Declan F. McCole, Annelies Geirnaert, Xuezhi Dai, Michael Scharl
Publikováno v:
Mucosal Immunology. 12:1336-1347
Fecal microbiota transfer (FMT) is a very efficient approach for the treatment of severe and recurring C. difficile infections. However, the beneficial effect of FMT in other disorders such as ulcerative colitis (UC) or Crohn's disease remains unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2894f0224f6a45b58ee4215e93a94b05
https://doi.org/10.1038/s41385-019-0201-1
https://doi.org/10.1038/s41385-019-0201-1
Autor:
Silvia Lang, Sima Ulugöl, Ana Montalban Arques, Roberto Manzini, Marianne R. Spalinger, Larissa Hering, Michael Scharl, Claudia Gottier
Publikováno v:
Inflamm Intest Dis
Background/Aims: Knockdown of protein tyrosine phosphatase nonreceptor type 2 (PTPN2) exaggerates IFN-γ-induced intestinal barrier defects, but mice constitutively lacking PTPN2 in epithelial cells (PTPN2xVilCre mice) do not show changes in epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d61b1e91f0143036929eb514b1e9a28
https://doi.org/10.1159/000499157
https://doi.org/10.1159/000499157
Autor:
Gabriel E. Leventhal, Onur Boyman, Vera Schellerer, Marlene Schwarzfischer, Michael Scharl, Michael Stürzl, Matthias Turina, Javier Conde, Elisabeth Naschberger, Silvia Lang, Egle Katkeviciute, Gerhard Rogler, Roberto Manzini, Sebastian Leibl, Marianne R. Spalinger, Philipp Busenhart, Larissa Hering, Kirstin Atrott, Mitchell P. Levesque, Ana Montalban-Arques, Achim Weber, Andreas Rickenbacher
Publikováno v:
J Clin Invest
Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) recently emerged as a promising cancer immunotherapy target. We set out to investigate the functional role of PTPN2 in the pathogenesis of human colorectal carcinoma (CRC), as its role in immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79509347ccc1e3ef426b9b00fd84ff2b
