Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Larissa D, Cunha"'
Autor:
Thais F.C. Fraga-Silva, Ualter G. Cipriano, Marcilio J. Fumagalli, Giseli F. Correa, Carlos A. Fuzo, Douglas dos-Santos, Fabiola L.A.C. Mestriner, Christiane Becari, Andrea Teixeira-Carvalho, Jordana Coelho-dos-Reis, Mayra G. Menegueti, Luiz T.M. Figueiredo, Larissa D. Cunha, Olindo A. Martins-Filho, Marcelo Dias-Baruffi, Maria Auxiliadora-Martins, Rita C. Tostes, Vania L.D. Bonato
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108366- (2023)
Summary: Airway epithelial cells (AEC) infected with SARS-CoV-2 may drive the dysfunction of macrophages during COVID-19. We hypothesized that the direct interaction of AEC with macrophages mediated by CD95/CD95L or indirect interaction mediated by I
Externí odkaz:
https://doaj.org/article/0fafe3cabae341cb9ed8ae07f59c750a
Autor:
Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://doaj.org/article/a119f5892a0d43a4859a59ccd6f0ea4d
Autor:
Ana CG Salina, Douglas dos-Santos, Tamara S Rodrigues, Marlon Fortes-Rocha, Edismauro G Freitas-Filho, Daniel L Alzamora-Terrel, Icaro MS Castro, Thais FC Fraga da Silva, Mikhael HF de Lima, Daniele C Nascimento, Camila M Silva, Juliana E Toller-Kawahisa, Amanda Becerra, Samuel Oliveira, Diego B Caetité, Leticia Almeida, Adriene Y Ishimoto, Thais M Lima, Ronaldo B Martins, Flavio Veras, Natália B do Amaral, Marcela C Giannini, Letícia P Bonjorno, Maria IF Lopes, Maira N Benatti, Sabrina S Batah, Rodrigo C Santana, Fernando C Vilar, Maria A Martins, Rodrigo L Assad, Sergio CL de Almeida, Fabiola R de Oliveira, Eurico Arruda Neto, Thiago M Cunha, José C Alves-Filho, Vania LD Bonato, Fernando Q Cunha, Alexandre T Fabro, Helder I Nakaya, Dario S Zamboni, Paulo Louzada-Junior, Rene DR Oliveira, Larissa D Cunha
Publikováno v:
eLife, Vol 11 (2022)
COVID-19 is a disease of dysfunctional immune responses, but the mechanisms triggering immunopathogenesis are not established. The functional plasticity of macrophages allows this cell type to promote pathogen elimination and inflammation or suppress
Externí odkaz:
https://doaj.org/article/90b9106f59824489a18e93537ba61d8e
Autor:
Sabrina S. Batah, Maíra N. Benatti, Li Siyuan, Wagner M. Telini, Jamile O. Barboza, Marcelo B. Menezes, Tales R. Nadai, Keyla S. G. Sá, Chirag M. Vaswani, Sahil Gupta, Dario S. Zamboni, Danilo T. Wada, Rodrigo T. Calado, Renê D. R. Oliveira, Paulo Louzada‐Junior, Maria Auxiliadora‐Martins, Flávio P. Veras, Larissa D. Cunha, Thiago M. Cunha, Rodrigo Luppino‐Assad, Marcelo L. Balancin, Sirlei S. Morais, Ronaldo B. Martins, Eurico Arruda, Fernando Chahud, Marcel Koenigkam Santos, Andrea A. Cetlin, Fernando Q. Cunha, Claudia dos Santos, Vera L. Capelozzi, Junya Fukuoka, Rosane Duarte Achcar, Alexandre T. Fabro
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/74cfa39831ad4d07aeb0b2b6fbc99819
Autor:
Maria Isabel Lopes, Leticia P Bonjorno, Marcela C Giannini, Natalia B Amaral, Pamella Indira Menezes, Saulo Musse Dib, Samara Libich Gigante, Maira N Benatti, Uebe C Rezek, Laerte L Emrich-Filho, Betania A A Sousa, Sergio C L Almeida, Rodrigo Luppino Assad, Flavio P Veras, Ayda Schneider, Tamara S Rodrigues, Luiz O S Leiria, Larissa D Cunha, Jose C Alves-Filho, Thiago M Cunha, Eurico Arruda, Carlos H Miranda, Antonio Pazin-Filho, Maria Auxiliadora-Martins, Marcos C Borges, Benedito A L Fonseca, Valdes R Bollela, Cristina M Del-Ben, Fernando Q Cunha, Dario S Zamboni, Rodrigo C Santana, Fernando C Vilar, Paulo Louzada-Junior, Rene D R Oliveira
Publikováno v:
RMD Open, Vol 7, Iss 1 (2021)
Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19 results in better outcomes.Design We present the results of a randomised, double-blinded, placebo-controlled clinical trial of colchicine for the treatment of
Externí odkaz:
https://doaj.org/article/4129e67bbc1e4c5388c06c260b55f530
Autor:
Bruna M.S. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camila M.S. Silva, Juliana C. Costa Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C. Martelossi Cebinelli, Naira L. Bibo, Daniel Macedo de Melo Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D.R. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b1fb8f63bdada259121518f1293a49
https://lirias.kuleuven.be/handle/20.500.12942/719126
https://lirias.kuleuven.be/handle/20.500.12942/719126
Autor:
Larissa D. Cunha, Alexandre L.N. Silva, Juliana M. Ribeiro, Danielle P.A. Mascarenhas, Gustavo F.S. Quirino, Leonardo L. Santos, Richard A. Flavell, Dario S. Zamboni
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 794-805 (2017)
Inflammasomes are multimeric protein complexes that initiate inflammatory cascades. Their activation is a hallmark of many infectious or inflammatory diseases. Their composition and activity are specified by proinflammatory stimuli. For example, the
Externí odkaz:
https://doaj.org/article/62ccbdc2f5e448ed85878cda8795228c
Autor:
Letícia de Almeida, Alexandre L. N. da Silva, Tamara S. Rodrigues, Samuel Oliveira, Adriene Y. Ishimoto, Amanda A. Seribelli, Amanda Becerra, Warrison A. Andrade, Marco A. Ataide, Camila C. S. Caetano, Keyla S. G. de Sá, Natália Pelisson, Ronaldo B. Martins, Juliano de Paula Souza, Eurico Arruda, Sabrina S. Batah, Ricardo Castro, Fabiani G. Frantz, Fernando Q. Cunha, Thiago M. Cunha, Alexandre T. Fabro, Larissa D. Cunha, Paulo Louzada-Junior, Rene D. R. de Oliveira, Dario S. Zamboni
Publikováno v:
Science advances. 8(37)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or asymptomatic COVID-19 in most cases, but some patients develop an excessive inflammatory process that can be fatal. As the NLRP3 inflammasome and additional inflammasomes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59753868c38960d9d73dc5ac7153b44
https://pubmed.ncbi.nlm.nih.gov/36103544
https://pubmed.ncbi.nlm.nih.gov/36103544
Autor:
Danielle P A Mascarenhas, Daiane M Cerqueira, Marcelo S F Pereira, Fernanda V S Castanheira, Talita D Fernandes, Graziele Z Manin, Larissa D Cunha, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006502 (2017)
Legionella pneumophila is a Gram-negative, flagellated bacterium that survives in phagocytes and causes Legionnaires' disease. Upon infection of mammalian macrophages, cytosolic flagellin triggers the activation of Naip/NLRC4 inflammasome, which culm
Externí odkaz:
https://doaj.org/article/fe345c0b68d746658de26232888e9bd3
Autor:
Bruna M. Silva, Flavio P. Veras, Giovanni F. Gomes, Seppe Cambier, Gabriel V. L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M. S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92d1955374f057b0fde192415d6d085
https://doi.org/10.1101/2022.07.03.498624
https://doi.org/10.1101/2022.07.03.498624