Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Larissa, Henze"'
Autor:
Annika Kayser, Annabell Wolff, Peggy Berlin, Lara Duehring, Larissa Henze, Ralf Mundkowski, Wendy Bergmann, Brigitte Müller-Hilke, Charlotte Wagner, Maja Huehns, Sonja Oehmcke-Hecht, Claudia Maletzki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Thromboembolic events are complications in cancer patients and hypercoagulability has been linked to the tissue factor (TF) pathway, making this an attractive target. Here, we investigated the effects of chemotherapeutics and CDK inhibitors
Externí odkaz:
https://doaj.org/article/0e2a2b478c654978834942a660548817
Autor:
Annabell Wolff, Paula Krone, Johanna Maennicke, Julia Henne, Sonja Oehmcke-Hecht, Caterina Redwanz, Wendy Bergmann-Ewert, Christian Junghanss, Larissa Henze, Claudia Maletzki
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102053- (2024)
Background: The CDK4/6 inhibitor abemaciclib is an FDA-approved agent and induces T-cell-mediated immunity. Previously, we confirmed the therapeutic potential of abemaciclib on mismatch repair-deficient (dMMR) tumors in mice. Here, we applied a proph
Externí odkaz:
https://doaj.org/article/eac5a1c76e4a4c1983f6fdb028e98cf2
Autor:
Larissa Henze, Luise Grunwald, Sabine Felser, Maria Witte, Christina Grosse-Thie, Catrin Roolf, Hugo Murua Escobar, Christian Junghanss
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
BackgroundAbdominal venous thromboses are rare thrombotic events with heterogeneous etiologies. They are related to myeloproliferative neoplasms (MPNs) in some patients and can occur as first signs of the disease. MPNs are characterized by mutations
Externí odkaz:
https://doaj.org/article/b50c2e711dcc4d15b77595056f66121d
Autor:
Benedikt Obermayer, Luisa Keilholz, Thomas Conrad, Marco Frentsch, Igor-Wolfgang Blau, Lam Vuong, Stella Lesch, Kamran Movasshagi, Carola Tietze-Stolley, Lucie Loyal, Larissa Henze, Olaf Penack, Ulrik Stervbo, Nina Babel, Simon Haas, Dieter Beule, Lars Bullinger, Friedrich Wittenbecher, Il-Kang Na
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The critical balance between intended and adverse effects in allogeneic hematopoietic stem cell transplantation (alloHSCT) depends on the fate of individual donor T-cells. To this end, we tracked αβT-cell clonotypes during stem cell mobilization tr
Externí odkaz:
https://doaj.org/article/d9bd5b08cfae4499a70a6f249b7d4866
Autor:
Larissa Henze, Julian Braun, Lil Meyer-Arndt, Karsten Jürchott, Maike Schlotz, Janine Michel, Marica Grossegesse, Maike Mangold, Manuela Dingeldey, Beate Kruse, Pavlo Holenya, Norbert Mages, Ulf Reimer, Maren Eckey, Karsten Schnatbaum, Holger Wenschuh, Bernd Timmermann, Florian Klein, Andreas Nitsche, Claudia Giesecke-Thiel, Lucie Loyal, Andreas Thiel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Currently available COVID-19 vaccines include inactivated virus, live attenuated virus, mRNA-based, viral vectored and adjuvanted protein-subunit-based vaccines. All of them contain the spike glycoprotein as the main immunogen and result in reduced d
Externí odkaz:
https://doaj.org/article/8d30110c924e4be5beac3a8eb0a4da1f
Autor:
Inken Salewski, Julia Henne, Leonie Engster, Paula Krone, Bjoern Schneider, Caterina Redwanz, Heiko Lemcke, Larissa Henze, Christian Junghanss, Claudia Maletzki
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Mismatch repair-deficient (dMMR) tumors show a good response toward immune checkpoint inhibitors (ICI), but developing resistance impairs patients’ outcomes. Here, we compared the therapeutic potential of an α-PD-L1 antibody with the CDK4/6 inhibi
Externí odkaz:
https://doaj.org/article/3e095849514f4debaf0bafdf03f37cc7
Autor:
Luise Grunwald, Christina Grosse-Thie, Sina Sender, Gudrun Knuebel, Saskia Krohn, Catrin Roolf, Christian Junghanss, Larissa Henze, Hugo Murua Escobar
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-4 (2020)
Abstract Myeloproliferative neoplasms are characterized by mutations in JAK2, MPL and CALR genes. Commonly in diagnostics and previous studies mainly sequencing and common PCR techniques under conventional detection limits are used. Splanchnic vein t
Externí odkaz:
https://doaj.org/article/cdfa19447b6e45e0b7b5beb463afe6ca
Autor:
Sonja Oehmcke-Hecht, Peggy Berlin, Brigitte Müller-Hilke, Bernd Kreikemeyer, Praveen Vasudevan, Larissa Henze, Valeria Khaimov, Brigitte Vollmar, Robert David, Claudia Maletzki
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112429- (2022)
The human contact system consists of plasma proteins, which - after contact to foreign surfaces - are bound to them, thereby activating the zymogens of the system into enzymes. This activation mechanism gave the system its name - contact system. It i
Externí odkaz:
https://doaj.org/article/69aca1565cde4d59bfde1a3f6acdc711
Publikováno v:
Annals of Cardiac Anaesthesia, Vol 24, Iss 2, Pp 244-246 (2021)
Congenital factor VII (FVII) deficiency is a rare bleeding disorder (RBD) with phenotypes ranging from asymptomatic state to life threatening bleeding episodes. There is no established recommendation for the perioperative management of patients sched
Externí odkaz:
https://doaj.org/article/fc92c67da965456e9da4e26b318f58bc
Autor:
Jan Torben Schille, Ingo Nolte, Julia Beck, Daria Jilani, Catrin Roolf, Anahit Pews-Davtyan, Arndt Rolfs, Larissa Henze, Matthias Beller, Bertram Brenig, Christian Junghanss, Ekkehard Schütz, Hugo Murua Escobar
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2021)
Castrate resistant prostate cancer in men shares several characteristics with canine prostate cancer (PCa). Due to current insufficient therapies, evaluating novel therapeutic agents for late-stage PCa is of considerable interest for both species. PD
Externí odkaz:
https://doaj.org/article/54cb6ffdb22744548f4214f34439892b