Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Larisa O, Metelytsia"'
Autor:
Alla D. Ocheretniuk, Larisa Kalashnikova, Ivan V. Semenyuta, Larisa O. Metelytsia, Sergiy Rogalsky, Maria M. Trush, Volodymyr Blagodatnyi, Oleksandr L. Kobzar, Diana Hodyna, Sergey I. Vdovenko
Publikováno v:
Medicinal Chemistry Research. 29:2181-2191
A series of long-chain imidazolium-based ionic liquids (ILs) 1-dodecyl-3-methylimidazolium chloride (1), 1,3-bis(octyloxycarbonylmethyl)imidazolium chloride (2) and 1-dodecyloxycarbonylmethyl-3-methyloxycarbonylmethylimidazolium chloride (3), were sy
Autor:
O.V. Shybyryn, K.Yu. Derevianko, Larisa O. Metelytsia, Sergiy Rogalsky, O.A. Aksenovska, Oksana Tarasyuk, T.M. Kamenieva
Publikováno v:
Catalysis and petrochemistry. :73-82
Cationic polymer polyhexamethylene guanidine hydrochloride (PHMG-Cl) is promising biocide that combines a broad spectrum of antimicrobial activity, mod-erate toxicity, as well as reasonable cost. It is widely used as an effective disinfect-ant in coo
Autor:
Larisa O. Metelytsia, Maryna V. Kachaeva, Volodymyr Brovarets, Oleksandr L. Kobzar, Vasyl Kovalishyn, Maria M. Trush, Alla D. Ocheretniuk
Publikováno v:
Current Drug Discovery Technologies. 16:204-209
Background: The incidence of invasive fungal infections caused by Candida spp. has increased continuously in recent decades, especially in populations of immunocompromised patients or individuals hospitalized with serious underlying diseases. Therefo
Publikováno v:
Ukrainian Biochemical Journal, Vol 91, Iss 3, Pp 78-89 (2019)
In our previous work, a number of new nitrogen-containing bisphosphonates (N-BPs) with high predicted and experimental antifungal activity were presented as potential Candida albicans farnesyl pyrophosphate synthase (FPPS) inhibitors. To confirm th
Autor:
Ivan V, Semenyuta, Maria M, Trush, Vasyl V, Kovalishyn, Sergiy P, Rogalsky, Diana M, Hodyna, Pavel, Karpov, Zhonghua, Xia, Igor V, Tetko, Larisa O, Metelytsia
Publikováno v:
International Journal of Molecular Sciences
Online Chemical Modeling Environment (OCHEM) was used for QSAR analysis of a set of ionic liquids (ILs) tested against multi-drug resistant (MDR) clinical isolate Acinetobacter baumannii and Staphylococcus aureus strains. The predictive accuracy of r
Autor:
O. V. Holovchenko, Larisa O. Metelytsia, Alla D. Ocheretniuk, Maria M. Trush, Volodymyr Brovarets, Oleksandr L. Kobzar, Larisa Kalashnikova, V. M. Prokopenko, Vasyl Kovalishyn
Publikováno v:
Letters in Drug Design & Discovery. 15:1259-1267
Background: Due to the increase of multidrug-resistant microorganisms, the search for biologically active molecules does not stop. In the present study, we developed the effective QSAR model which allows a quick search of new potential Staphylococcus
Autor:
Evgeniya O. Lobko, Ivan V. Semenyuta, Maria M. Trush, Sergiy Rogalsky, Larisa O. Metelytsia, Sergey I. Vdovenko
Publikováno v:
Journal of Molecular Structure. 1137:692-699
The interaction between human serum albumin (HSA) and synthesized imidazolium and pyridinium based ionic liquids (ILs), as good potential microbial growth inhibitors, was investigated by spectroscopic techniques combined with molecular docking analys
Autor:
Larisa O. Metelytsia, Oleg Dzhuzha, Jean-François Bardeau, Sergiy Rogalsky, Tetiana Cherniavska, Irina A. Morozovskaya, Iryna Kopernyk, Lyudmyla Petrus, Alexander A. Protasov, Mariia Boretska, Oksana Tarasyuk, Larisa Kalashnikova
Publikováno v:
Environmental Toxicology and Chemistry. 36:2543-2551
A new polymeric biocide polyhexamethylene guanidine (PHMG) molybdate has been synthesized. The obtained cationic polymer has limited water solubility of 0.015 g/100 mL and is insoluble in paint solvents. The results of acute toxicity studies indicate
Publikováno v:
Reports of the National Academy of Sciences of Ukraine. :103-108
Autor:
Maria M. Trush, Larisa O. Metelytsia, V. M. Prokopenko, Volodymyr Blagodatnyi, Volodymyr Brovarets, Diana Hodyna, Stepan G. Pilyo, Vasyl Kovalishyn
Publikováno v:
Ukrainian Biochemical Journal, Vol 88, Iss 4, Pp 57-65 (2016)
The regression QSAR models were built to predict the antimicrobial activity of new thiazole derivatives. Compounds with high predicting activity were synthesized and evaluated against Gram-positive and Gram-negative bacteria and fungi. 1,3-Thiazole-4