Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Larisa Kizima"'
Autor:
Rakhee Sachdeva, Narender Kumar, Vivian Brache, Barbara A. Friedland, Marlena Plagianos, Shimin Zhang, Larisa Kizima, Leila Cochon, Ana Sofía Tejada Tabar, Ann Blanc, Ruth B. Merkatz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract To identify biomarkers of hormonal contraceptive (HC) use in urine and saliva, we conducted a pilot study with 30 women initiating levonorgestrel (LNG) containing combined oral contraceptives (COCs) or depot medroxyprogesterone acetate (DMPA
Externí odkaz:
https://doaj.org/article/9ce99506d9404150bf8f4b210102e8fc
Autor:
Natalia Teleshova, Marla J Keller, José A Fernández Romero, Barbara A Friedland, George W Creasy, Marlena G Plagianos, Laurie Ray, Patrick Barnable, Larisa Kizima, Aixa Rodriguez, Nadjet Cornejal, Claudia Melo, Gearoff Cruz Rodriguez, Sampurna Mukhopadhyay, Giulia Calenda, Shweta U Sinkar, Thierry Bonnaire, Asa Wesenberg, Shimin Zhang, Kyle Kleinbeck, Kenneth Palmer, Mohcine Alami, Barry R O'Keefe, Patrick Gillevet, Hong Hur, Yupu Liang, Gabriela Santone, Raina N Fichorova, Tamara Kalir, Thomas M Zydowsky
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261775 (2022)
HIV pre-exposure prophylaxis (PrEP) is dominated by clinical therapeutic antiretroviral (ARV) drugs. Griffithsin (GRFT) is a non-ARV lectin with potent anti-HIV activity. GRFT's preclinical safety, lack of systemic absorption after vaginal administra
Externí odkaz:
https://doaj.org/article/71d1f80746cd4044a9318e97651b89ec
Autor:
Nina Derby, Manjari Lal, Meropi Aravantinou, Larisa Kizima, Patrick Barnable, Aixa Rodriguez, Manshun Lai, Asa Wesenberg, Shweta Ugaonkar, Keith Levendosky, Olga Mizenina, Kyle Kleinbeck, Jeffrey D. Lifson, M. Melissa Peet, Zachary Lloyd, Michael Benson, Walid Heneine, Barry R O’Keefe, Melissa Robbiani, Elena Martinelli, Brooke Grasperge, James Blanchard, Agegnehu Gettie, Natalia Teleshova, José A. Fernández-Romero, Thomas M. Zydowsky
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Safety and efficacy remain important challenges for non-antiretroviral-based microbicides. Here, Derby et al. show that a Griffithsin-Carrageenan fast dissolving vaginal insert provides on-demand protection against SHIV infections in macaques, paving
Externí odkaz:
https://doaj.org/article/8d4f42eeb266482fa22316c03e392e44
Autor:
Guillermo Villegas, Giulia Calenda, Shweta Ugaonkar, Shimin Zhang, Larisa Kizima, Olga Mizenina, Agegnehu Gettie, James Blanchard, Michael L Cooney, Melissa Robbiani, José A Fernández-Romero, Thomas M Zydowsky, Natalia Teleshova
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159332 (2016)
Women need multipurpose prevention products (MPTs) that protect against sexually transmitted infections (STIs) and provide contraception. The Population Council has developed a prototype intravaginal ring (IVR) releasing the non-nucleoside reverse tr
Externí odkaz:
https://doaj.org/article/2c7ce7258bc743d49918758692207898
Autor:
Mayla Hsu, Brandon F Keele, Meropi Aravantinou, Noa Krawczyk, Samantha Seidor, Ciby J Abraham, Shimin Zhang, Aixa Rodriguez, Larisa Kizima, Nina Derby, Ninochka Jean-Pierre, Olga Mizenina, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael J Piatak, Jeffrey D Lifson, José A Fernández-Romero, Thomas M Zydowsky, Melissa Robbiani
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89300 (2014)
When microbicides used for HIV prevention contain antiretroviral drugs, there is concern for the potential emergence of drug-resistant HIV following use in infected individuals who are either unaware of their HIV infection status or who are aware but
Externí odkaz:
https://doaj.org/article/b1f84d839f2a4832b1c088e64864c11d
Autor:
Patrick Barnable, Giulia Calenda, Louise Ouattara, Agegnehu Gettie, James Blanchard, Ninochka Jean-Pierre, Larisa Kizima, Aixa Rodríguez, Ciby Abraham, Radhika Menon, Samantha Seidor, Michael L Cooney, Kevin D Roberts, Rhoda Sperling, Michael Piatak, Jeffrey D Lifson, Jose A Fernandez-Romero, Thomas M Zydowsky, Melissa Robbiani, Natalia Teleshova
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108109 (2014)
To extend our observations that single or repeated application of a gel containing the NNRTI MIV-150 (M) and zinc acetate dihydrate (ZA) in carrageenan (CG) (MZC) inhibits vaginal transmission of simian/human immunodeficiency virus (SHIV)-RT in macaq
Externí odkaz:
https://doaj.org/article/2e9ac8a52d7e461e9520d4b7745640d7
Autor:
Larisa Kizima, Aixa Rodríguez, Jessica Kenney, Nina Derby, Olga Mizenina, Radhika Menon, Samantha Seidor, Shimin Zhang, Keith Levendosky, Ninochka Jean-Pierre, Pavel Pugach, Guillermo Villegas, Brian E Ford, Agegnehu Gettie, James Blanchard, Michael Piatak, Jeffrey D Lifson, Gabriela Paglini, Natalia Teleshova, Thomas M Zydowsky, Melissa Robbiani, José A Fernández-Romero
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94547 (2014)
Prevalent infection with human herpes simplex 2 (HSV-2) or human papillomavirus (HPV) is associated with increased human immunodeficiency virus (HIV) acquisition. Microbicides that target HIV as well as these sexually transmitted infections (STIs) ma
Externí odkaz:
https://doaj.org/article/9f20173b1dae4edd8e9a6f19a6dbcc8a
Autor:
Jessica Kenney, Meropi Aravantinou, Rachel Singer, Mayla Hsu, Aixa Rodriguez, Larisa Kizima, Ciby J Abraham, Radhika Menon, Samantha Seidor, Anne Chudolij, Agegnehu Gettie, James Blanchard, Jeffrey D Lifson, Michael Piatak, Jose A Fernández-Romero, Thomas M Zydowsky, Melissa Robbiani
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15835 (2011)
Repeated use, coitus-independent microbicide gels that do not contain antiretroviral agents also used as first line HIV therapy are urgently needed to curb HIV spread. Current formulations require high doses (millimolar range) of antiretroviral drugs
Externí odkaz:
https://doaj.org/article/c33767af459e4d63b82956f69b733d81
Autor:
Patrick Barnable, Sampurna Mukhopadhyay, Larisa Kizima, Narender Kumar, Marlena Plagianos, Saurabh Mehandru, Natalia Teleshova
Publikováno v:
AIDS Research and Human Retroviruses.
Autor:
Aixa Rodriguez, Keith Levendosky, Larisa Kizima, Shweta R. Ugaonkar, Thomas M. Zydowsky, José A. Fernández-Romero, Olga Mizenina, Manjari Lal, Manshun Lai, Asa Wesenberg
Publikováno v:
Journal of Pharmaceutical Sciences. 107:2601-2610
Precoital, on-demand topical microbicides to reduce a woman's risk of sexually transmitted infections have been in development for nearly 3 decades, but no product has been approved due to acceptability issues and poor adherence in clinical trials. W