Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Larisa Emelyanova"'
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 13, Iss 2, Pp 105-130 (2021)
Over past few years, there has been a dramatic increase in studying physiological mechanisms of the activity of various signaling low-molecular molecules that directly or indirectly initiate adaptive changes in the cardiovascular system cells (CVSC)
Externí odkaz:
https://doaj.org/article/0a8216bbe6654a6eadcf99ab0f045196
Autor:
Larisa Emelyanova, Amar Sra, Eric G. Schmuck, Amish N. Raval, Francis X. Downey, Arshad Jahangir, Farhan Rizvi, Gracious R. Ross
Publikováno v:
ESC Heart Failure, Vol 6, Iss 5, Pp 1027-1040 (2019)
Abstract Aims Fibroblast to myofibroblast trans‐differentiation with altered bioenergetics precedes cardiac fibrosis (CF). Either prevention of differentiation or promotion of de‐differentiation could mitigate CF‐related pathologies. We determi
Externí odkaz:
https://doaj.org/article/f91db7acf6c4456597f2c60d6328089d
Autor:
Farhan Rizvi, Claudia C. Preston, Larisa Emelyanova, Mohammed Yousufuddin, Maria Viqar, Omar Dakwar, Gracious R. Ross, Randolph S. Faustino, Ekhson L. Holmuhamedov, Arshad Jahangir
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
Background Age‐related heart diseases are significant contributors to increased morbidity and mortality. Emerging evidence indicates that mitochondria within cardiomyocytes contribute to age‐related increased reactive oxygen species (ROS) generat
Externí odkaz:
https://doaj.org/article/e30e7c94a5c54f1888225464b3fc1d1e
Autor:
Gracious R. Ross, Tanvir Bajwa, Stacie Edwards, Larisa Emelyanova, Farhan Rizvi, Ekhson L. Holmuhamedov, Paul Werner, Francis X. Downey, A. Jamil Tajik, Arshad Jahangir
Publikováno v:
Biology Open, Vol 6, Iss 3, Pp 326-332 (2017)
Excessive cardiac fibrosis, characterized by increased collagen-rich extracellular matrix (ECM) deposition, is a major predisposing factor for mechanical and electrical dysfunction in heart failure (HF). The human ventricular fibroblast (hVF) remodel
Externí odkaz:
https://doaj.org/article/3dcb7d0a7e4c4925913ded2133ab2440
Autor:
Ulugbek Negmadjanov, Alisher Holmuhamedov, Larisa Emelyanova, Hao Xu, Farhan Rizvi, Gracious R. Ross, A. Jamil Tajik, Yang Shi, Ekhson Holmuhamedov, Arshad Jahangir
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 3, Iss 4, Pp 187-198 (2016)
Purpose: Excessive fibrosis has been suggested to result from persistence of fibroblasts in injured tissue due to impaired apoptosis, but signaling pathways are not fully defined. Methods: Suppression of apoptotic cell death following transforming gr
Externí odkaz:
https://doaj.org/article/5f1e660c634a49f1a98becd7c11ea4d4
Autor:
Larisa Emelyanova, Anna Boukatina, Cheryl Myers, Janice Oyarzo, Joseph Lustgarten, Yang Shi, Arshad Jahangir
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0217045 (2019)
PurposeHigh calorie intake leads to obesity, a global socio-economic and health problem, reaching epidemic proportion in children and adolescents. Saturated and monounsaturated fatty acids from animal (lard) fat are major components of the western-pa
Externí odkaz:
https://doaj.org/article/5035f98e8113405abba068c7b565aa03
Autor:
Ulugbek Negmadjanov, Zarko Godic, Farhan Rizvi, Larisa Emelyanova, Gracious Ross, John Richards, Ekhson L Holmuhamedov, Arshad Jahangir
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123046 (2015)
Cytokine-dependent activation of fibroblasts to myofibroblasts, a key event in fibrosis, is accompanied by phenotypic changes with increased secretory and contractile properties dependent on increased energy utilization, yet changes in the energetic
Externí odkaz:
https://doaj.org/article/07f32d746705442181d951802340d3d6
Autor:
Catherine Warner, Arshad Jahangir, Sirisha Kaushik, David C Kress, Farhan Rizvi, Elizabeth Stoeckl, Stacie Kroboth, Larisa Emelyanova, Gracious R Ross, Teodore Rudic, Xiaowen Bai, Zeljko J. Bosnjak, A. Jamil Tajik, Yasheng Yan
Publikováno v:
Translational Research. 229:5-23
Metformin is the first-line medication for treatment of type 2 diabetes and has been shown to reduce heart damage and death. However, mechanisms by which metformin protects human heart remain debated. The aim of the study was to evaluate the cardiopr
Autor:
Francis X Downey, Amar Sra, Amish N. Raval, Eric G. Schmuck, Gracious R Ross, Larisa Emelyanova, Arshad Jahangir, Farhan Rizvi
Publikováno v:
ESC Heart Failure, Vol 6, Iss 5, Pp 1027-1040 (2019)
ESC Heart Failure
ESC Heart Failure
Aims Fibroblast to myofibroblast trans‐differentiation with altered bioenergetics precedes cardiac fibrosis (CF). Either prevention of differentiation or promotion of de‐differentiation could mitigate CF‐related pathologies. We determined wheth
Autor:
Larisa Emelyanova, Arshad Jahangir, Farhan Rizvi, Gracious R. Ross, Omar Dakwar, Mohammed Yousufuddin, Randolph S. Faustino, Maria Viqar, Claudia C. Preston, Ekhson Holmuhamedov
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Age‐related heart diseases are significant contributors to increased morbidity and mortality. Emerging evidence indicates that mitochondria within cardiomyocytes contribute to age‐related increased reactive oxygen species (ROS) generat