TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca ² .

Autor: Woolums BM; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., McCray BA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sung H; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tabuchi M; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sullivan JM; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ruppell KT; Neurobiology Department, UMass Medical School, Worcester, MA, USA., Yang Y; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mamah C; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Aisenberg WH; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Saavedra-Rivera PC; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Larin BS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lau AR; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Robinson DN; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Xiang Y; Neurobiology Department, UMass Medical School, Worcester, MA, USA., Wu MN; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sumner CJ; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. csumner1@jhmi.edu.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. csumner1@jhmi.edu., Lloyd TE; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlloyd4@jhmi.edu.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlloyd4@jhmi.edu.

Publikováno v: Nature communications [Nat Commun] 2020 May 29; Vol. 11 (1), pp. 2679. Date of Electronic Publication: 2020 May 29.

[Multifractionated radiotherapy of esophageal cancer].

Autor: Leskov VP, Larin BS

Publikováno v: Meditsinskaia radiologiia [Med Radiol (Mosk)] 1989 Mar; Vol. 34 (3), pp. 11-4.