Zobrazeno 1 - 10 of 622 pro vyhledávání: '"Larhammar, M."'
1
Akademický článek
DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response.
Autor: Yulyaningsih E; Denali Therapeutics, South San Francisco, United States., Suh JH; Denali Therapeutics, South San Francisco, United States., Fanok M; Denali Therapeutics, South San Francisco, United States., Chau R; Denali Therapeutics, South San Francisco, United States., Solanoy H; Denali Therapeutics, South San Francisco, United States., Takahashi R; Denali Therapeutics, South San Francisco, United States., Bakardjiev AI; Denali Therapeutics, South San Francisco, United States., Becerra I; Denali Therapeutics, South San Francisco, United States., Benitez NB; Denali Therapeutics, South San Francisco, United States., Chiu CL; Denali Therapeutics, South San Francisco, United States., Davis SS; Denali Therapeutics, South San Francisco, United States., Dowdle WE; Denali Therapeutics, South San Francisco, United States., Earr T; Denali Therapeutics, South San Francisco, United States., Estrada AA; Denali Therapeutics, South San Francisco, United States., Gill A; Denali Therapeutics, South San Francisco, United States., Ha C; Denali Therapeutics, South San Francisco, United States., Haddick PCG; Denali Therapeutics, South San Francisco, United States., Henne KR; Denali Therapeutics, South San Francisco, United States., Larhammar M; Denali Therapeutics, South San Francisco, United States., Leung AW; Denali Therapeutics, South San Francisco, United States., Maciuca R; Denali Therapeutics, South San Francisco, United States., Memarzadeh B; Denali Therapeutics, South San Francisco, United States., Nguyen HN; Denali Therapeutics, South San Francisco, United States., Nugent AA; Denali Therapeutics, South San Francisco, United States., Osipov M; Denali Therapeutics, South San Francisco, United States., Ran Y; Denali Therapeutics, South San Francisco, United States., Rebadulla K; Denali Therapeutics, South San Francisco, United States., Roche E; Denali Therapeutics, South San Francisco, United States., Sandmann T; Denali Therapeutics, South San Francisco, United States., Wang J; Denali Therapeutics, South San Francisco, United States., Lewcock JW; Denali Therapeutics, South San Francisco, United States., Scearce-Levie K; Denali Therapeutics, South San Francisco, United States., Kane LA; Denali Therapeutics, South San Francisco, United States., Sanchez PE; Denali Therapeutics, South San Francisco, United States.
Publikováno v: ELife [Elife] 2024 Sep 17; Vol. 12. Date of Electronic Publication: 2024 Sep 17.
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2
Akademický článek
SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons.
Autor: Miyamoto T; Denali Therapeutics Inc, South San Francisco, California, USA., Kim C; Denali Therapeutics Inc, South San Francisco, California, USA., Chow J; Denali Therapeutics Inc, South San Francisco, California, USA., Dugas JC; Denali Therapeutics Inc, South San Francisco, California, USA., DeGroot J; Denali Therapeutics Inc, South San Francisco, California, USA., Bagdasarian AL; Denali Therapeutics Inc, South San Francisco, California, USA., Thottumkara AP; Denali Therapeutics Inc, South San Francisco, California, USA., Larhammar M; Denali Therapeutics Inc, South San Francisco, California, USA., Calvert ME; Denali Therapeutics Inc, South San Francisco, California, USA., Fox BM; Denali Therapeutics Inc, South San Francisco, California, USA., Lewcock JW; Denali Therapeutics Inc, South San Francisco, California, USA. Electronic address: lewcock@dnli.com., Kane LA; Denali Therapeutics Inc, South San Francisco, California, USA. Electronic address: kane@dnli.com.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Feb; Vol. 300 (2), pp. 105630. Date of Electronic Publication: 2024 Jan 08.
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4
Akademický článek
Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis.
Autor: Craig RA 2nd; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Fox BM; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Hu C; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Lexa KW; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Osipov M; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Thottumkara AP; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Larhammar M; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Miyamoto T; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Rana A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Kane LA; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Yulyaningsih E; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Solanoy H; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Nguyen H; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Chau R; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Earr T; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Kajiwara Y; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Fleck D; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Lucas A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Haddick PCG; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Takahashi RH; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Tong V; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Wang J; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Canet MJ; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Poda SB; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Scearce-Levie K; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Srivastava A; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Sweeney ZK; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States., Xu M; Department of Chemistry, WuXi AppTec Co., Ltd., 168 Nanhai Road, 10th Avenue, Tianjin TEDA, Tianjin 300457, China., Zhang R; Department of Chemistry, WuXi AppTec Co., Ltd., 168 Nanhai Road, 10th Avenue, Tianjin TEDA, Tianjin 300457, China., He J; Department of Chemistry, WuXi AppTec Co., Ltd., 168 Nanhai Road, 10th Avenue, Tianjin TEDA, Tianjin 300457, China., Lei Y; Department of Chemistry, WuXi AppTec Co., Ltd., 168 Nanhai Road, 10th Avenue, Tianjin TEDA, Tianjin 300457, China., Zhuo Z; Department of Chemistry, WuXi AppTec Co., Ltd., 168 Nanhai Road, 10th Avenue, Tianjin TEDA, Tianjin 300457, China., de Vicente J; Denali Therapeutics Inc., 161 Oyster Point Blvd., South San Francisco, California 94080, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Dec 22; Vol. 65 (24), pp. 16290-16312. Date of Electronic Publication: 2022 Dec 05.
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5
Akademický článek
HuD regulates apoptosis in N2a cells by regulating Msi2 expression.
Autor: Gaikwad, Naina1,2 (AUTHOR), Sarwade, Rucha1,2 (AUTHOR), Halder, Sourav1,2 (AUTHOR), Agarwal, Gaurav1,2 (AUTHOR), Seshadri, Vasudevan1 (AUTHOR) seshadriv@nccs.res.in
Publikováno v: PLoS ONE. 12/16/2024, Vol. 19 Issue 12, p1-17. 17p.
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6
Akademický článek
Identification of pathological pathways centered on circRNA dysregulation in association with irreversible progression of Alzheimer's disease.
Autor: Wang, Feng1 (AUTHOR), Li, Yangping1 (AUTHOR), Shen, Huifeng1 (AUTHOR), Martinez-Feduchi, Paula1 (AUTHOR), Ji, Xingyu2 (AUTHOR), Teng, Peng2 (AUTHOR), Krishnakumar, Siddharth1 (AUTHOR), Hu, Jian1 (AUTHOR), Chen, Li3 (AUTHOR), Feng, Yue2 (AUTHOR) yfeng@emory.edu, Yao, Bing1 (AUTHOR) bing.yao@emory.edu
Publikováno v: Genome Medicine. 11/12/2024, Vol. 16 Issue 1, p1-24. 24p.
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7
Akademický článek
Genetic diversity and signatures of selection in Icelandic horses and Exmoor ponies.
Autor: Sigurðardóttir, Heiðrún1,2 (AUTHOR) heidrun.sigurdardottir@slu.se, Ablondi, Michela3 (AUTHOR), Kristjansson, Thorvaldur2 (AUTHOR), Lindgren, Gabriella1,4 (AUTHOR), Eriksson, Susanne1 (AUTHOR)
Publikováno v: BMC Genomics. 10/22/2024, Vol. 25 Issue 1, p1-18. 18p.
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8
Akademický článek
Cell Death and Neurodegeneration.
Autor: Andreone BJ; Denali Therapeutics, South San Francisco, California 94080, USA., Larhammar M; Denali Therapeutics, South San Francisco, California 94080, USA., Lewcock JW; Denali Therapeutics, South San Francisco, California 94080, USA.
Publikováno v: Cold Spring Harbor perspectives in biology [Cold Spring Harb Perspect Biol] 2020 Feb 03; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 03.
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9
Akademický článek
An Overview About Mesenchymal Stem Cell Exosomes and their Applications in Biological Research.
Autor: Rabea, Amany A.1 Amanyrabea1@gmail.com, El Deeb, Mona1
Publikováno v: Egyptian Journal of Histology. Sep2024, Vol. 47 Issue 3, p907-922. 16p.
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10
Akademický článek
Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits.
Autor: Perry S; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Larhammar M; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden klas.kullander@neuro.uu.se martin.larhammar@gmail.com., Vieillard J; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Nagaraja C; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Hilscher MM; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Tafreshiha A; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Rofo F; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Caixeta FV; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden., Kullander K; Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden klas.kullander@neuro.uu.se martin.larhammar@gmail.com.
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2019 Mar 06; Vol. 39 (10), pp. 1771-1782. Date of Electronic Publication: 2018 Dec 21.
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