Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease

Autor: Rochais, Christophe, Lecoutey, Cédric, Lalut, Julien, Davis, Audrey, Duval, Emilie, Gaven, Florence, Largillière, Stacy, Née, Gérald, Corvaisier, Sophie, Sopkova de Oliveira Santos, Jana, Since, Marc, Freret, Thomas, Legrand, Romain, Callizot, Noëlle, Claeysen, Sylvie, Boulouard, Michel, Dallemagne, Patrick

Publikováno v: In European Journal of Medicinal Chemistry 15 December 2024 280

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A Dual-Task Paradigm Combining Physical and Cognitive Training in Mice: Application to Aging.

Autor: Attoh-Mensah E; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France.; University of Limoges, HAVAE, UR 20217, F-87000 Limoges, France., Huret A; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Leger M; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Loggia G; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France.; Normandie University, UNICAEN, CHU de Caen, Department of Geriatrics, Caen, 14000, France., Nee G; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Largilliere S; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Zuba D; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Chavoix C; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Schumann-Bard P; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France., Freret T; Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU de Caen, 14000 Caen, France.

Publikováno v: Aging and disease [Aging Dis] 2024 Feb 14. Date of Electronic Publication: 2024 Feb 14.