Microbial Complexity of Oral Cavity of Healthy Dogs Identified by Mass Spectrometry and Next-Generation Sequencing

Autor: Fábio V. R. Portilho, Juliano Nóbrega, Beatriz O. de Almeida, André R. Mota, Carolina L. de Paula, Fernando J. P. Listoni, Sandra M. G. Bosco, Alana L. Oliveira, Maria de Lourdes R. S. Cunha, Márcio G. Ribeiro

Publikováno v: Animals, Vol 13, Iss 15, p 2467 (2023)

The high complexity of the oral microbiota of healthy dogs and the close exposure of humans to companion animals represent a risk of the transmission of potential zoonotic microorganisms to humans, especially through dog bites, including multidrug-re

Externí odkaz: https://doaj.org/article/46fc56fa8083422181bfdf79f00e6f3b

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The carbohydrate-active enzyme database: functions and literature

Autor: Nicolas Terrapon, Elodie Drula, Vincent Lombard, Marie-Line Garron, Suzan Dogan, Bernard Henrissat

Publikováno v: Nucleic Acids Research
Drula, E, Garron, M L, Dogan, S, Lombard, V, Henrissat, B & Terrapon, N 2022, ' The carbohydrate-active enzyme database: functions and literature ', Nucleic Acids Research, vol. 50, no. D1, gkab1045, pp. D571-D577 . https://doi.org/10.1093/nar/gkab1045
Nucleic Acids Research, 2022, 50 (D1), pp.D571-D577. ⟨10.1093/nar/gkab1045⟩

Thirty years have elapsed since the emergence of the classification of carbohydrate-active enzymes in sequence-based families that became the CAZy database over 20 years ago, freely available for browsing and download at www.cazy.org. In the era of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95cd8d68c72bb70debe6bfc79445b25
https://doi.org/10.1093/nar/gkab1045

Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses

Autor: Daniel J. Rader, Sekar Kathiresan, Joseph E. Hadaya, Rajat M. Gupta, John Yu, Deepak Atri, Vivian S. Lee-Kim, Virendar K. Kaushik, Hong-Hee Won, Minxian Wang, Colin W. Garvie, Kevin Trindade, Amit Khera, Bryan T. MacDonald, Nadine H. Elowe, Pradeep Natarajan, Olle Melander

Publikováno v: Circulation: Genomic and Precision Medicine. 14

Background: Corin is a protease expressed in cardiomyocytes that plays a key role in salt handling and intravascular volume homeostasis via activation of natriuretic peptides. It is unknown if Corin loss-of-function (LOF) is causally associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77cf011950cb03226e890012d1d7049c
https://doi.org/10.1161/circgen.121.003399

Large-scale sequencing of SARS-CoV-2 genomes from one region allows detailed epidemiology and enables local outbreak management

Autor: Colin S Brown, Maria Diaz, Luke Bedford, Ana P. Tedim, Steven Rudder, Meera Chand, Muhammad Yasir, Luke Griffith, Will Potter, Rachel Gilroy, Nicholas M. Thomson, Rachael Stanley, Emma Meader, Robert A Kingsley, Ana Victoria Gutierrez, S. J. Louise Smith, Thanh Le-Viet, John Wain, Ian G. Charles, Alexander J. Trotter, Alp Aydin, Ngozi Elumogo, Justin O'Grady, Gemma L. Kay, Reenesh Prakash, Dheeraj K. Sethi, Rose K Davidson, Claire Stuart, Evelien M. Adriaenssens, Alison E Mather, Dinesh Aggarwal, Nabil-Fareed Alikhan, Andrew J. Page, Lizzie Meadows, Anastasia Kolyva, David Baker, Mark A. Webber, Lindsay Coupland, Leonardo de Oliveira Martins, Andrew Bell, Tracey E. Swingler, Samir Dervisevic

Publikováno v: Microbial genomics

The COVID-19 pandemic has spread rapidly throughout the world. In the UK, the initial peak was in April 2020; in the county of Norfolk (UK) and surrounding areas, which has a stable, low-density population, over 3200 cases were reported between March

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da28c640aaddbdb285135735082f409b
https://doi.org/10.1099/mgen.0.000589