Zobrazeno 1 - 10
of 1 498
pro vyhledávání: '"Large animal model"'
Autor:
Marina Martinez-Vargas, Arun Saini, Subhashree Pradhan, Luis Gardea, Barbara Stoll, Inka C. Didelija, K. Vinod Vijayan, Trung C. Nguyen, Miguel A. Cruz
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract Background Sepsis can lead to coagulopathy and microvascular thrombosis. Prior studies, including ours, reported an increased level of extracellular vimentin in blood derived from septic patients. Moreover, we identified the contribution of
Externí odkaz:
https://doaj.org/article/06bff839c9884f288ab548f6817a7e4b
Autor:
Valentina Zollet, Isabel Arenas Hoyos, Stefanie Hirsiger, Bilal Ben Brahim, Maria Francesca Petrucci, Daniela Casoni, Junhua Wang, Rolf Spirig, Kay Nettelbeck, Luisana Garcia, Lena Fuest, Esther Vögelin, Mihai Constantinescu, Robert Rieben
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIschemia/reperfusion injury (IRI) is a complex pathological process, triggered by the restoration of blood flow following an interrupted blood supply. While restoring the blood flow is the only option to salvage the ischemic tissue, reperfu
Externí odkaz:
https://doaj.org/article/ff6e9d30bdf54f5aaa05a8b473c490fb
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 245-257 (2024)
Angela Giselvania,1,2 Vetnizah Juniantito,3 Heri Wibowo,4 Trifonia Pingkan Siregar,5 Soehartati Gondhowiardjo2 1Doctoral Program in Biomedical Sciences, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; 2Department of Radiation Oncology,
Externí odkaz:
https://doaj.org/article/4b7a9dfb04f74a689d245abec6c09395
Autor:
Kristian Stærk, Brit Schrøder, Louise Kruse Jensen, Troels Petersen, Thomas Emil Andersen, Lene Feldskov Nielsen
Publikováno v:
BJUI Compass, Vol 5, Iss 2, Pp 217-223 (2024)
Abstract Objective The objective of this study is to characterize bladder mucosal trauma associated with intermittent catheterization with conventional eyelet catheters (CECs) and to assess if a microhole zone catheter (MHZC) design concept reduces t
Externí odkaz:
https://doaj.org/article/0722dbae35a64f4abd6c6765036cac6a
Publikováno v:
Brain Multiphysics, Vol 6, Iss , Pp 100088- (2024)
Traumatic brain injury (TBI) is a major public health challenge. Up to 90 % of TBIs are on the mild spectrum of TBI (mTBI), where diagnosis is a major challenge. Majority of studies in this field have been conducted on human subjects, which inherentl
Externí odkaz:
https://doaj.org/article/5c89ae653cef4d999fb49241d9ab3b26
Autor:
Lei Zhang, Isabel Arenas Hoyos, Anja Helmer, Yara Banz, Cédric Zubler, Ioana Lese, Stefanie Hirsiger, Mihai Constantinescu, Robert Rieben, Mitra Gultom, Radu Olariu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundVascularized composite allotransplantation (VCA) offers the potential for a biological, functional reconstruction in individuals with limb loss or facial disfigurement. Yet, it faces substantial challenges due to heightened immune rejection
Externí odkaz:
https://doaj.org/article/9ff07474364446e08b2ca0c1527c091d
Autor:
Felix Wiedmann, Max Jamros, Valerie Herlt, Amelie Paasche, Manuel Kraft, Moritz Beck, Merten Prüser, Atilla Erkal, Maren Harder, Marcin Zaradzki, Jasmin Soethoff, Matthias Karck, Norbert Frey, Constanze Schmidt
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
BackgroundElectrocardiographic (ECG) features of left bundle branch (LBB) block (LBBB) can be observed in up to 20%–30% of patients suffering from heart failure with reduced ejection fraction. However, predicting which LBBB patients will benefit fr
Externí odkaz:
https://doaj.org/article/709a03ae53bc42ab80780c19469bb3d4
Autor:
Daisuke Onohara, MD, PhD, Matthew Hagen, PhD, Samantha Louey, PhD, George Giraud, MD, PhD, Sonnet Jonker, PhD, Muralidhar Padala, PhD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 698-707 (2023)
Objective: The in utero no flow/no grow hypothesis postulates that reduced inflow of blood into the left ventricle due to a stenotic mitral valve could lead to ventricular hypoplasia and hypoplastic left heart syndrome. This has been demonstrated in
Externí odkaz:
https://doaj.org/article/31015283eadb4b4a96395f45133de81f
Autor:
Kazutoshi Okamoto, Hitomi Matsunari, Kazuaki Nakano, Kazuhiro Umeyama, Koki Hasegawa, Ayuko Uchikura, Shuko Takayanagi, Masahito Watanabe, Jun Ohgane, Michael Stirm, Mayuko Kurome, Nikolai Klymiuk, Masaki Nagaya, Eckhard Wolf, Hiroshi Nagashima
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 451-458 (2023)
Introduction: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disorder caused by mutation in the dystrophin gene (DMD) on the X chromosome. Female DMD carriers occasionally exhibit symptoms such as muscle weakness and heart failure. H
Externí odkaz:
https://doaj.org/article/51df675076934a228d6302859f500d01
Autor:
Mengjun Wang, MD, Xiao Lu, PhD, Ling Han, BS, José A. Diaz, MD, Seshadri Raju, MD, Ghassan S. Kassab, PhD
Publikováno v:
JVS - Vascular Science, Vol 5, Iss , Pp 100200- (2024)
Objective: This study describes a novel swine model of venous thromboembolism (VTE) with reflux-induced venous hypertension. Methods: Six pigs underwent disruption of the tricuspid chordae tendineae to create reflux and venous hypertension in the fem
Externí odkaz:
https://doaj.org/article/76aff4a3fed947a6b61439da5084c277