yEvo: Experimental evolution in high school classrooms selects for novel mutations and epistatic interactions that impact clotrimazole resistance in S. cerevisiae

Autor: Students y, Maitreya J. Dunham, Josephine M. Boyer, Warwick Ar, Walson M, Angela Shang-Mei Hickey, Matthew B. Taylor, Paul A. Rowley, Skophammer R, Large Crl

Antifungal resistance in pathogenic fungi is a growing global health concern. Non-pathogenic laboratory strains of Saccharomyces cerevisiae are a useful model for studying mechanisms of antifungal resistance that are relevant to understanding the sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29cf9d15187cc4029c1663660a7f49cf
https://doi.org/10.1101/2021.05.02.442375

Overdrive is essential for targeted sperm elimination by Segregation Distorter .

Autor: Ridges JT; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Bladen J; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., King TD; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Brown NC; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Large CRL; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Cooper JC; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Jones AJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Loppin B; Laboratoire de Biologie et Modélisation de la Cellule, École Normale Supérieure de Lyon, CNRS UMR5239, Université Claude Bernard Lyon 1, Lyon, France., Dubruille R; Laboratoire de Biologie et Modélisation de la Cellule, École Normale Supérieure de Lyon, CNRS UMR5239, Université Claude Bernard Lyon 1, Lyon, France., Phadnis N; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 06. Date of Electronic Publication: 2024 Jun 06.

yEvo: experimental evolution in high school classrooms selects for novel mutations that impact clotrimazole resistance in Saccharomyces cerevisiae.

Autor: Taylor MB; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.; Program in Biology, Loras College, Dubuque, IA 52001, USA., Skophammer R; Westridge School, Pasadena, CA 91105, USA., Warwick AR; Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA., Geck RC; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Boyer JM; Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA., Walson M; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Large CRL; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.; UW Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA., Hickey AS; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.; Present address: Department of Genetics, Stanford University, Biomedical Innovations Building, Palo Alto, CA 94304, USA., Rowley PA; Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA., Dunham MJ; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.

Publikováno v: G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Nov 04; Vol. 12 (11).

Effect of the Ala234Asp replacement in mitochondrial branched-chain amino acid aminotransferase on the production of BCAAs and fusel alcohols in yeast.

Autor: Koonthongkaew J; Division of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan., Toyokawa Y; Division of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan., Ohashi M; Nara Prefecture Institute of Industrial Development, 129-1 Kashiwagi-cho, Nara, Nara, 630-8031, Japan., Large CRL; Department of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, WA, 98195, USA., Dunham MJ; Department of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, WA, 98195, USA., Takagi H; Division of Biological Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan. hiro@bs.naist.jp.

Publikováno v: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2020 Sep; Vol. 104 (18), pp. 7915-7925. Date of Electronic Publication: 2020 Aug 10.

Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of Saccharomyces cerevisiae .

Autor: Sanchez JC; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195.; Bioscience Division, Los Alamos National Laboratory, Los Alamos New Mexico 87544., Ollodart A; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195., Large CRL; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195., Clough C; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195., Alvino GM; Department of Genome Sciences, University of Washington, Seattle, Washington 98195., Tsuchiya M; Department of Pathology, University of Washington, Seattle, Washington 98195., Crane M; Department of Pathology, University of Washington, Seattle, Washington 98195., Kwan EX; Department of Genome Sciences, University of Washington, Seattle, Washington 98195., Kaeberlein M; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195.; Department of Pathology, University of Washington, Seattle, Washington 98195., Dunham MJ; Department of Genome Sciences, University of Washington, Seattle, Washington 98195.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195., Raghuraman MK; Department of Genome Sciences, University of Washington, Seattle, Washington 98195., Brewer BJ; Department of Genome Sciences, University of Washington, Seattle, Washington 98195 bbrewer@gs.washington.edu.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195.

Publikováno v: Genetics [Genetics] 2019 Sep; Vol. 213 (1), pp. 229-249. Date of Electronic Publication: 2019 Jul 10.