Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Larbi Elmchichi"'
Autor:
Mohammed BOUACHRINE, Larbi Elmchichi, Abdellah El Aissouq, Assia BELHASSAN, Hanane Zaki, Abdelkrim Ouammou, Tahar Lakhlifi
Publikováno v:
Chemical Review and Letters, Vol 4, Iss 3, Pp 145-152 (2021)
Studies and scientific research indicate that the platelet-activating factor (PAF) is a major pro-inflammatory mediator in the initiation and development of cancer. There is also evidence confirming that PAF is an integral part of suppressing the imm
Externí odkaz:
https://doaj.org/article/5a91c7b43321492694839ff91fb1d1f4
Autor:
Reda EL-Mernissi, Khalil EL Khatabi, Ayoub Khaldan, Soukaina Bouamrane, Larbi ElMchichi, Mohammed Aziz Ajana, Tahar Lakhlifi, Mohammed Bouachrine
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 14, Iss 1 (2022)
Cancer is one of the world's causes of death, which requires the discovery of new molecules likely to become anticancer drugs. In this study, a three–dimensional quantitative structure-activity relationship is employed to study eighteen compounds o
Externí odkaz:
https://doaj.org/article/d9d51de2187242589f9d6da6307fd060
Publikováno v:
Journal of Chemistry, Vol 2020 (2020)
For their biological properties and particularly for their anticancer activities, chalcones are widely studied. In this work, we have submitted diverse sets of chalcone derivatives to the 3D-QSAR (3-dimensional quantitative structural-activity relati
Externí odkaz:
https://doaj.org/article/aef4ecc7a5354e71abddadc7fb467cfb
Autor:
Kamal Tabti, Soukayna Baammi, Larbi ElMchichi, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi
Publikováno v:
Structural Chemistry. 33:1019-1039
Autor:
kamal Tabti, larbi Elmchichi, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi
These are supplementary files oftrajectories of DENV virus inhibitory activity from molecular dynamics simulation to the preprint/paper "HQSAR, CoMFA, CoMSIA docking studies and simulation MD on quinazolines/quinolines derivatives for DENV virus inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5847bae9497c578c474b84f8569734c
Autor:
Larbi Elmchichi, Amina Goudzal, Abdellah El Aissouq, Fatima En-nahli, Mohammed Bouachrine, Oussama Chedadi, Fouad Khalil, Rania Kasmi, Abdelkrim Ouammou
Publikováno v:
Journal of Solution Chemistry. 50:808-822
Glycogen synthase kinase-3 beta (GSK-3β) is implicated in abnormal hyperphosphorylation of the tau protein and its inhibitors may be a promising therapeutic approach for treating Alzheimer’s disease. Here, a series of C-glycosylfavone derivatives
Autor:
Mohammed Aziz Ajana, Khalil El khatabi, REDA EL-MERNISSI, Ayoub Khaldan, Larbi ElMchichi, Tahar Lakhlifi, Mohammed Bouachrine
Publikováno v:
Egyptian Journal of Chemistry.
Autor:
Kamal Tabti, Larbi Elmchichi, Abdelouahid Sbai, Hamid Maghat, Mohammed bouachrine, Tahar Lakhlifi
In this study, quantitative mathematical models were established to understand the relationship between a series of 26 quinazoline / quinoline derivative and their biological activity against DENV virus using 3D-QSAR and HQSAR analysis. According to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23fbf664532e8f8df6a224db6f12230
https://doi.org/10.21203/rs.3.rs-1465758/v1
https://doi.org/10.21203/rs.3.rs-1465758/v1
Autor:
Kamal TABTI, Abdelouahid SBAI, Larbi ELMCHICHI, Hamid MAGHAT, Tahar LAKHLIFI, Mohammed BOUACHRINE
The p53 is a tumor suppressor protein that adjusts cell cycle and growth arrest as well as genes that restore DNA damage and apoptosis. Murine double minute 2 (MDM2) is a main p53 antagonist. We created a novel QSAR model using a series of highly act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d11f7c2762d55020a243df4e95c4c427
https://doi.org/10.21203/rs.3.rs-1233496/v1
https://doi.org/10.21203/rs.3.rs-1233496/v1
Autor:
Kamal Tabti, Larbi Elmchichi, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi
Cancer is one of the greatest challenges that worry the minds of scientists and threatens human life. Despite the presence of several drugs on the market, their effectiveness remains limited by its resistance. In this research, the Monte Carlo approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae40bcedd1224c34c7e35c455820322f