Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure–activity relationship, and action mechanism studies

Autor: Moret, Vincent, Laras, Younes, Cresteil, Thierry, Aubert, Geneviève, Ping, Dou Q., Di, Chen, Barthélémy-Requin, Magali, Béclin, Christophe, Peyrot, Vincent, Allegro, Diane, Rolland, Amandine, De Angelis, Francesca, Gatti, Evelina, Pierre, Philippe, Pasquini, Luca, Petrucci, Eleonora, Testa, Ugo, Kraus, Jean-Louis

Publikováno v: In European Journal of Medicinal Chemistry 2009 44(2):558-567

Synthesis of Quinoline Dicarboxylic Esters as Biocompatible Fluorescent Tags

Autor: Favre-Besse, Franck-Cyril, Poirel, Odile, Bersot, Tiphaine, Kim-Grellier, Elodie, Daumas, Stéphanie, El Mestikawy, Salah, Laras, Younes, Hugues, Vincent, Chandrasekaran, Yogesh, Blanchard-Desce, Mireille, Acher, Francine, Pietrancosta, Nicolas

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2012, 77 (18), pp.8294-8302. ⟨10.1021/jo301652j⟩
Journal of Organic Chemistry, 2012, 77 (18), pp.8294-8302. ⟨10.1021/jo301652j⟩

A series of dicarboxylic quinoline derivatives bearing electron-releasing or -withdrawing substituents have been synthesized using mono- or/and biphasic methodologies. By controlling the regioselectivity of addition into our electrophilic intermediat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131335be5dbf5ea48a03b2ccac772362
https://doi.org/10.1021/jo301652j

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1,1′-Xylyl bis-1,4,8,11-tetraaza cyclotetradecane: A new potential copper chelator agent for neuroprotection in Alzheimer’s disease. Its comparative effects with clioquinol on rat brain copper distribution

Autor: Moret, Vincent, Laras, Younes, Pietrancosta, Nicolas, Garino, Cédrik, Quéléver, Gilles, Rolland, Amandine, Mallet, Bernard, Norreel, Jean-Chrétien, Kraus, Jean-Louis

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2006 16(12):3298-3301

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