Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Larance Ronsard"'
Autor:
Eike-Christian Wamhoff, Larance Ronsard, Jared Feldman, Grant A. Knappe, Blake M. Hauser, Anna Romanov, James Brett Case, Shilpa Sanapala, Evan C. Lam, Kerri J. St. Denis, Julie Boucau, Amy K. Barczak, Alejandro B. Balazs, Michael S. Diamond, Aaron G. Schmidt, Daniel Lingwood, Mark Bathe
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Protein-based virus-like particles (P-VLPs) are commonly used to spatially organize antigens and enhance humoral immunity through multivalent antigen display. However, P-VLPs are thymus-dependent antigens that are themselves immunogenic and
Externí odkaz:
https://doaj.org/article/a903d94958bc48e7ac6e79ace0aa2f9a
Autor:
Larance Ronsard, Ashraf S. Yousif, Faez Amokrane Nait Mohamed, Jared Feldman, Vintus Okonkwo, Caitlin McCarthy, Julia Schnabel, Timothy Caradonna, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, Aaron Schmidt, Daniel Lingwood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Low affinity is common for germline B cell receptors (BCR) seeding development of broadly neutralizing antibodies (bnAbs) that engage hypervariable viruses, including HIV. Antibody affinity selection is also non-homogenizing, insuring the su
Externí odkaz:
https://doaj.org/article/a0cd14beccbe4760b5405b63d07f7e21
Autor:
Larance Ronsard, Ashraf S. Yousif, Julianne Peabody, Vintus Okonkwo, Pascal Devant, Alemu Tekewe Mogus, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, David Peabody, Bryce Chackerian, Daniel Lingwood
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The ligand-binding surface of the B cell receptor (BCR) is formed by encoded and non-encoded antigen complementarity determining regions (CDRs). Genetically reproducible or ‘public’ antibodies can arise when the encoded CDRs play deterministic ro
Externí odkaz:
https://doaj.org/article/c501fb4e290e4b8e90012f7b9a25ca18
Autor:
Maya Sangesland, Ashraf S. Yousif, Larance Ronsard, Samuel W. Kazer, Alex Lee Zhu, G. James Gatter, Matthew R. Hayward, Ralston M. Barnes, Maricel Quirindongo-Crespo, Daniel Rohrer, Nils Lonberg, Douglas Kwon, Alex K. Shalek, Daniel Lingwood
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108065- (2020)
Summary: B cell receptors (BCRs) display a combination of variable (V)-gene-encoded complementarity determining regions (CDRs) and adaptive/hypervariable CDR3 loops to engage antigens. It has long been proposed that the former tune for recognition of
Externí odkaz:
https://doaj.org/article/4869d22e49344399b1979bd3c854bad0
Autor:
Madhu Khanna, Sanjesh Saini, Malini Shariff, Larance Ronsard, Jitender K. Singh, Harish Kumar
Publikováno v:
Data in Brief, Vol 24, Iss , Pp - (2019)
This data represents the effect of miR-155 on the expression of commonly used housekeeping genes, GAPDH, Beta Actin, RPL13A, and U6. The human miR-155 and control RNA were transfected to A549 cells by electroporation. Expression of these genes was co
Externí odkaz:
https://doaj.org/article/33c19d33f4ce4952bde1130814ebfe1b
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
HIV-1 Tat transactivates viral genes through strong interaction with TAR RNA. The stem-loop bulged region of TAR consisting of three nucleotides at the position 23–25 and the loop region consisting of six nucleotides at the position 30–35 are ess
Externí odkaz:
https://doaj.org/article/1fea4b612f3846eeaa85a729236a13a5
Autor:
Larance Ronsard, Akhil C. Banerjea, Nilanjana Ganguli, Vivek K. Singh, Kumaravel Mohankumar, Tripti Rai, Subhashree Sridharan, Sankar Pajaniradje, Binod Kumar, Devesh Rai, Suhnrita Chaudhuri, Mohane S. Coumar, Vishnampettai G. Ramachandran
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
HIV-1 evades host defense through mutations and recombination events, generating numerous variants in an infected patient. These variants with an undiminished virulence can multiply rapidly in order to progress to AIDS. One of the targets to interven
Externí odkaz:
https://doaj.org/article/d9979a2d577b4862b054424fb4aadbc0
Autor:
Larance Ronsard, Ashraf S. Yousif, Janani Ramesh, N. Sumi, Matthew Gorman, Vishnampettai G. Ramachandran, Akhil C. Banerjea
Publikováno v:
Viruses, Vol 11, Iss 11, p 976 (2019)
Human immunodeficiency virus (HIV) is a global health concern affecting millions of individuals with a wide variety of currently circulating subtypes affecting various regions of the globe. HIV relies on multiple regulatory proteins to modify the hos
Externí odkaz:
https://doaj.org/article/20f1bf0cec92458b8e9d6b3cb7694f61
Publikováno v:
Diseases, Vol 7, Iss 1, p 15 (2019)
Autophagy is a regular and substantial “clear-out process„ that occurs within the cell and that gets rid of debris that accumulates in membrane-enclosed vacuoles by using enzyme-rich lysosomes, which are filled with acids that degrade the content
Externí odkaz:
https://doaj.org/article/bb302b6511c94c97b73227568ffb79f5
Autor:
Larance Ronsard, Sneh Lata, Jyotsna Singh, Vishnampettai G Ramachandran, Shukla Das, Akhil C Banerjea
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85452 (2014)
BACKGROUND: Designing an ideal vaccine against HIV-1 has been difficult due to enormous genetic variability as a result of high replication rate and lack of proofreading activity of reverse transcriptase leading to emergence of genetic variants and r
Externí odkaz:
https://doaj.org/article/ba7b592df58c4df7ad8801f29c5c115c