Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lara Thieme"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The incidence of spondylodiscitis has witnessed a significant increase in recent decades. Surgical intervention becomes necessary in case of bone destruction to remove infected tissue and restore spinal stability, often involving the implant
Externí odkaz:
https://doaj.org/article/cd8a5f9317744fe2aa581f62d2a51e38
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Galleria mellonella larvae have emerged as an invertebrate model for investigating bacterial pathogenesis and potential therapies, addressing ethical concerns related to mammalian models. This model has the advantage of having a simple gut m
Externí odkaz:
https://doaj.org/article/070956c3e36944bd916babc6df9774ba
Autor:
Elsie Quansah, Anuradha Ramoji, Lara Thieme, Kamran Mirza, Bianca Goering, Oliwia Makarewicz, Astrid Heutelbeck, Tobias Meyer-Zedler, Mathias W. Pletz, Michael Schmitt, Jürgen Popp
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Non-linear imaging modalities have enabled us to obtain unique morpho-chemical insights into the tissue architecture of various biological model organisms in a label-free manner. However, these imaging techniques have so far not been applied
Externí odkaz:
https://doaj.org/article/146750441e3043f1b089d7b2d4fd6f62
Autor:
Szilvia Neuhaus, Andrea T. Feßler, Ralf Dieckmann, Lara Thieme, Mathias W. Pletz, Stefan Schwarz, Sascha Al Dahouk
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1455 (2022)
Disinfection is a key strategy to reduce the burden of infections. The contact of bacteria to biocides—the active substances of disinfectants—has been linked to bacterial adaptation and the development of antimicrobial resistance. Currently, ther
Externí odkaz:
https://doaj.org/article/355b2bd62db34579b03e6a034f22ea57
Autor:
Lara Thieme, Anita Hartung, Kristina Tramm, Julia Graf, Riccardo Spott, Oliwia Makarewicz, Mathias W. Pletz
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Colony forming unit (CFU) determination by agar plating is still regarded as the gold standard for biofilm quantification despite being time- and resource-consuming. Here, we propose an adaption of the high-throughput Start-Growth-Time (SGT) method f
Externí odkaz:
https://doaj.org/article/5cc00c23b5dc495f94073930837e48b2
Publikováno v:
Microorganisms, Vol 9, Iss 10, p 2150 (2021)
Enterococcus faecalis infective endocarditis is commonly treated with intravenous ampicillin/ceftriaxone combination therapy. Ampicillin, however, is unsuitable for outpatient parenteral antibiotic therapy (OPAT) regimens due to its instability in 24
Externí odkaz:
https://doaj.org/article/6523dbc141af4ebda39aab5aa9698a16
Autor:
Kamran A. Mirza, Sebastian Jacob, Sandor Nietzsche, Oliwia Makarewicz, Mathias W. Pletz, Lara Thieme
SummaryPurposeGalleria mellonellalarvae have emerged as an invertebrate model for studying bacterial pathogenesis and novel therapeutic options due to ethical concerns associated with the use of mammalian models such as mice. The benefits of usingG.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31096c7aa31299ea2f018d213f9e4777
https://doi.org/10.1101/2023.03.27.534343
https://doi.org/10.1101/2023.03.27.534343
Publikováno v:
Journal of Molecular Structure. 1277:134831
It was shown that several metabolic states of bacteria with various characteristics such as chemical composition participate in the formation of biofilms. To study the connections and differences among different bacterial metabolic states, five speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1333806cd85736e4430641f001204292
https://doi.org/10.1016/j.molstruc.2022.134831
https://doi.org/10.1016/j.molstruc.2022.134831
Autor:
Lara Thieme
Publikováno v:
Research Outreach. :134-137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d789a2a7f9be80104a701aeeb98469c
https://doi.org/10.32907/ro-113-134137
https://doi.org/10.32907/ro-113-134137
Publikováno v:
Journal of Antimicrobial Chemotherapy.
Background The unfavourable safety profile of aminoglycosides and the synergistic effects observed in vitro have prompted the development of novel dual β-lactam therapies, e.g. ampicillin/ceftriaxone or ampicillin/ceftaroline, for the treatment of E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db8c6770afd2df34a1fc2617aeba61c
https://doi.org/10.1093/jac/dkaa129
https://doi.org/10.1093/jac/dkaa129