Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lara S. Shamieh"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1790:1067-1074
Studies in a variety of model organisms indicate that nutrient signaling is tightly coupled to longevity. In nutrient replete conditions, organisms develop, grow, and age quickly. When nutrients become sparse as with dietary restriction, growth and d
Autor:
Billie R. Ocampo, Shiwen Chen, George L. Sutphin, Lara S. Shamieh, Shirley Park, Matt Kaeberlein, Devon Chandler-Brown, Haeri Choi, Erica D. Smith, Anna Le
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 6 (2015)
Frontiers in Genetics, Vol 6 (2015)
The response to osmotic stress is a highly conserved process for adapting to changing environmental conditions. Prior studies have shown that hyperosmolarity by addition of sorbitol to the growth medium is sufficient to increase both chronological an
Autor:
Heather Schneider, Shannon Klum, Haeri Choi, Matt Kaeberlein, Lara S. Shamieh, Devon Chandler-Brown
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e82543 (2013)
PLoS ONE, Vol 8, Iss 12, p e82543 (2013)
The anticonvulsant ethosuximide has been previously shown to increase life span and promote healthspan in the nematode Caenorhabditis elegans at millimolar concentrations. Here we report that following exposure to ultraviolet irradiation at 254 nm, e
Publikováno v:
Advances in experimental medicine and biology. 694
Appropriate regulation of mRNA translation is essential for growth and survival and the pathways that regulate mRNA translation have been highly conserved throughout eukaryotic evolution. Translation is controlled by a complex set of mechanisms actin
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781441970015
Appropriate regulation of mRNA translation is essential for growth and survival and the pathways that regulate mRNA translation have been highly conserved throughout eukaryotic evolution. Translation is controlled by a complex set of mechanisms actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a5e438fdd7d0f74f74dfb782947d98
https://doi.org/10.1007/978-1-4419-7002-2_2
https://doi.org/10.1007/978-1-4419-7002-2_2
Autor:
Matt Kaeberlein, Lara S. Shamieh
Publikováno v:
The Comparative Biology of Aging ISBN: 9789048134649
The target of rapamycin (TOR) kinase defines a highly conserved nutrient-response pathway that is known to modulate longevity in invertebrate organisms. Multiple mutations in this pathway that reduce TOR signaling have been reported to increase life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c6c49d40b9ce64e0c0037e7eb92279
https://doi.org/10.1007/978-90-481-3465-6_7
https://doi.org/10.1007/978-90-481-3465-6_7
Autor:
Alexander Huh, George L. Sutphin, Christina Davis, Lara S. Shamieh, Katherine A. Steinkraus, Devon Chandler-Brown, Ranjana Mehta, Fresnida J. Ramos, Matt Kaeberlein
Publikováno v:
Science (New York, N.Y.). 324(5931)
Anti-Aging Several human neurodegenerative diseases, such as Alzheimer's and Huntington's, are caused by aberrant protein aggregation. These disorders typically develop after the fifth decade of life, suggesting a connection with the aging process. I
Autor:
Lara S. Shamieh
The role of erbB receptors in breast cancer. The establishment and progression of breast cancer is controlled by receptors for peptide growth factors and for estrogens (I). Of these receptors, the Epidermal Growth Factor Receptor (EGFR) family has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7a1ade0b5beccbb5c8c3d959e681dc
https://doi.org/10.21236/ada468024
https://doi.org/10.21236/ada468024