Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Lara Rizzotto"'
Autor:
Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, Joao A. G. Duarte, Esther A. Zaal, Ali Talebi, Matteo Rossi, Pierre-René Körner, Lara Rizzotto, Stijn Moens, Wout De Wispelaere, Regina E. M. Baiden-Amissah, Gabe S. Sonke, Hugo M. Horlings, Guy Eelen, Emanuele Berardi, Johannes V. Swinnen, Celia R. Berkers, Peter Carmeliet, Diether Lambrechts, Ben Davidson, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Metabolic reprogramming is associated with cancer development and therapy resistance. Here, the authors show that downregulation of the serine biosynthesis enzyme PHGDH in a fraction of patients is associated with relapse in platinum-treated ovarian
Externí odkaz:
https://doaj.org/article/ea6155ed60d848d191feda4d57429fb3
Autor:
Francesco Nicoli, Valentina Finessi, Mariaconcetta Sicurella, Lara Rizzotto, Eleonora Gallerani, Federica Destro, Aurelio Cafaro, Peggy Marconi, Antonella Caputo, Barbara Ensoli, Riccardo Gavioli
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e77746 (2013)
T cells are functionally compromised during HIV infection despite their increased activation and proliferation. Although T cell hyperactivation is one of the best predictive markers for disease progression, its causes are poorly understood. Anti-tat
Externí odkaz:
https://doaj.org/article/f013185ea74446f6ba28d77399bc9d31
Autor:
Alessio Branchini, Lara Rizzotto, Guglielmo Mariani, Mariasanta Napolitano, Mario Lapecorella, Muriel Giansily-Blaizot, Rosella Mari, Alessandro Canella, Mirko Pinotti, Francesco Bernardi
Publikováno v:
Haematologica, Vol 97, Iss 5 (2012)
We report 2 asymptomatic homozygotes for the nonsense p.R462X mutation affecting the carboxy-terminus of coagulation factor VII (FVII, 466 aminoacids). FVII levels of 3–5% and 2.7±0.4% were found in prothrombin time-based and activated factor X (F
Externí odkaz:
https://doaj.org/article/8544a4911daa4c26a411ea0865c250f4
Autor:
Tom van Nyen, Mélanie Planque, Lilian van Wagensveld, Esther Zaal, Lara Rizzotto, Wout de Wispelaere, Ali Talebi, Pierre-René Körner, Gabe Sonke, Hugo Horlings, Ben Davidson, Johan Swinnen, Celia Berkers, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant
Publikováno v:
Ovarian cancer.
Autor:
Xilal Y. Rima, Gautham Sarathy, Lara Rizzotto, Anagh Kulkarni, Dario Palmieri, Meisam Naeimi Kararoudi, Eduardo Reátegui, Bhuvaneswari Ramaswamy, Eswar Shankar
Publikováno v:
Cancer Research. 83:332-332
Triple negative breast cancer (TNBC) cells overexpress enhancer of zeste homolog 2 (EZH2) the catalytic subunit of polycomb repressive complex 2 (PRC2). EZH2 is a potential driver of TNBC metastasis, and its high expression strongly associates with t
Autor:
Eleonora Leucci, Emilie Calonne, Rachel Deplus, Ghanem Elias Ghanem, Robert L. Ross, Soizic Garaud, Luis Augusto Teixeira, Clémence Al Wardi, Yacine Bareche, Jacqueline Lehmann-Che, Martine Duterque-Coquillaud, Zena Wimana, Alexander Koch, Kateryna Shostak, Xavier Leroy, Martin Bizet, Renato Morandini, Alain Chariot, Mingzhou Guo, Evelyne Collignon, Mohammad Krayem, Pascale Putmans, Pierre Close, Yan Jia, Gaurav Dube, Karen Willard-Gallo, Jean-Christophe Marine, François Fuks, Jana Jeschke, Françoise Rothé, Christos Sotiriou, Bi-Feng Yuan, Lara Rizzotto, Gerben Menschaert, Nitesh Kumar Singh, Christine Desmedt, Patrick A. Limbach, Bouchra Hassabi
Publikováno v:
Nature Cancer, 2(6), 611-+. Nature Publishing Group
Nature Cancer, 2 (6
Nature Cancer, 2 (6
Post-transcriptional modifications of RNA constitute an emerging regulatory layer of gene expression. The demethylase fat mass- and obesity-associated protein (FTO), an eraser of N-6-methyladenosine (m(6)A), has been shown to play a role in cancer, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664ad06e0e6411b736f6c75e2983edd7
https://cris.maastrichtuniversity.nl/en/publications/390eaf3a-0be7-4885-9c94-0bc066fd2220
https://cris.maastrichtuniversity.nl/en/publications/390eaf3a-0be7-4885-9c94-0bc066fd2220
Autor:
Christophe Deroose, Lien Spans, Eleonora Leucci, G. De Meerleer, Anita Thomas, Uwe Himmelreich, Uros Milenkovic, S. Joniau, Wouter Everaerts, A.S. Van Rompuy, Asif Muneer, Joren Vanthoor, Maarten Albersen, Herlinde Dumez, I. Vanden Bempt, Christopher Cawthorne, Lara Rizzotto, I. Tsaur
Publikováno v:
European Urology Open Science, Vol 19, Iss, Pp e293-e294 (2020)
Autor:
Roberto Vendramin, Panagiotis Karras, Angelina Konnova, Sara Adnane, Lara Rizzotto, Vasiliki Katopodi, Sonia Cinque, Francesca Maria Bosisio, Zorica Knezevic, Eleonora Leucci, Jean-Christophe Marine, Oliver Bechter, Ewout Demesmaeker
SummaryTherapy resistance remains a major clinical challenge for the management of metastatic melanoma. Here we show that activation of the Integrated Stress Response (ISR), which we show is common in drug-tolerant and resistant melanoma, promotes se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e95a946aef573fefbf1222a5519b32a
https://doi.org/10.1101/2020.06.26.173492
https://doi.org/10.1101/2020.06.26.173492
Autor:
Asif Muneer, Christophe Deroose, Maarten Albersen, Christopher Cawthorne, Willy Gsell, Lara Rizzotto, Anita Thomas, Uwe Himmelreich, Joren Vanthoor, Eleonora Leucci, Lien Spans, Anne-Sophie Van Rompuy
Publikováno v:
European urology. 78(2)
Autor:
Deepa Sampath, Tzung Huei Lai, John C. Byrd, Arianna Bottoni, Rosa Lapalombella, Jennifer A. Woyach, Clara D. Bloomfield, Lara Rizzotto
Publikováno v:
Leukemia & Lymphoma. 59:1461-1465
The Bruton tyrosine kinase (BTK) is constitutively activated by the Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) or the Toll-like receptor 9 (TLR9) in acute myelogenous leukemi...