Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Lara Paracchini"'
Autor:
Martina Vescio, Lara Paracchini, Luca Beltrame, Maurizio D’Incalci, Sergio Marchini, Linda Pattini
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 7, Iss , Pp 100088- (2023)
High grade serous ovarian carcinoma (HGSOC) is a systemic malignancy characterized by metastatic lesions that spread within the peritoneal cavity. Despite initial sensibility to platinum-based chemotherapy, more than 80% of patients experience a rela
Externí odkaz:
https://doaj.org/article/6fc85128e64f4a40b87e1afa50f762cf
Autor:
Laura Mannarino, Federica Mirimao, Nicolò Panini, Lara Paracchini, Sergio Marchini, Luca Beltrame, Rosy Amodeo, Federica Grosso, Roberta Libener, Irene De Simone, Giovanni L. Ceresoli, Paolo A. Zucali, Monica Lupi, Maurizio D’Incalci
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-9 (2022)
Abstract Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different selectivity displayed by the various MPM histotypes to this phys
Externí odkaz:
https://doaj.org/article/5bde7304069647c4a6e5b02fd41387ae
Autor:
Lara Paracchini, Luca Beltrame, Lucia Boeri, Federica Fusco, Paolo Caffarra, Sergio Marchini, Diego Albani, Gianluigi Forloni
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-20 (2018)
Abstract Background The typical familial form of Alzheimer’s disease (FAD) accounts for about 5% of total Alzheimer’s disease (AD) cases. Presenilins (PSEN1 and PSEN2) and amyloid-β (A4) precursor protein (APP) genes carry all reported FAD-linke
Externí odkaz:
https://doaj.org/article/30ede54f6a134ce398fff6dcba2adf24
Autor:
Valentina Iori, Anand M. Iyer, Teresa Ravizza, Luca Beltrame, Lara Paracchini, Sergio Marchini, Milica Cerovic, Cameron Hill, Mariella Ferrari, Massimo Zucchetti, Monica Molteni, Carlo Rossetti, Riccardo Brambilla, H. Steve White, Maurizio D'Incalci, Eleonora Aronica, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 99, Iss , Pp 12-23 (2017)
We recently discovered that forebrain activation of the IL-1 receptor/Toll-like receptor (IL-1R1/TLR4) innate immunity signal plays a pivotal role in neuronal hyperexcitability underlying seizures in rodents. Since this pathway is activated in neuron
Externí odkaz:
https://doaj.org/article/6e1282d045224c0cb2029a5afa349aa9
Autor:
Sergio Marchini, Chiara Romualdi, Maurizio D'Incalci, Costantino Mangioni, Sergio Pecorelli, Enrico Sartori, Germana Tognon, Dionyssios Katsaros, Rodolfo Milani, Patrizia Perego, Giorgio Cattoretti, Duccio Cavalieri, Laura Zanotti, Ilaria Fuso Nerini, Mariacristina Di Marino, Lorenzo Ceppi, Luca Clivio, Luca Beltrame, Gabriele Sales, Paolo Martini, Antonella Ravaggi, Eliana Bignotti, Lara Paracchini, Robert Fruscio, Enrica Calura
PDF file - 330K, The clinical stratification of the 76 selected patients used for the integrative analysis and the MAGIA2 complete results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5e611b29e4e04084ecb9c53b249ec4
https://doi.org/10.1158/1078-0432.22447031
https://doi.org/10.1158/1078-0432.22447031
Autor:
Chiara Romualdi, Sergio Marchini, Maurizio D'Incalci, Chiara Ghimenti, Costantino Mangioni, Lorenzo Ceppi, Laura Mannarino, Stefano Cagnin, Giovanna Chiorino, Ilaria Craparotta, Dionyssios Katsaros, Patrizia Perego, Enrico Sartori, Franco E. Odicino, Eliana Bignotti, Antonella Ravaggi, Gabriele Sales, Enrica Calura, Luca Beltrame, Robert Fruscio, Maurizia Mello-Grand, Giulia Caratti, Lara Paracchini, Paolo Martini
Purpose: Stage I epithelial ovarian cancer (EOC) represents about 10% of all EOCs and is characterized by good prognosis with fewer than 20% of patients relapsing. As it occurs less frequently than advanced-stage EOC, its molecular features have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a0cd5da6ee861322569a50d2abd97e
https://doi.org/10.1158/1078-0432.c.6525615.v1
https://doi.org/10.1158/1078-0432.c.6525615.v1
Autor:
Sergio Marchini, Giulia Siravegna, Maurizio D'Incalci, Chiara Romualdi, Marta Jaconi, Marco Adorni, Mariachiara Paderno, Martina Delle Marchette, Davide Ippolito, Fabio Landoni, Robert Fruscio, Alessia Inglesi, Tommaso Grassi, Luca Beltrame, Lara Paracchini
Heatmap of SCNA profiles of tumor tissues and plasma. Genome-wide patterns distribution of SCNA in plasma (PL-1) and matched tumor tissues from 35 patients at diagnosis (T0). X- axis depicts the loci of the 23 chromosomes, while y-axis indicates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cfd6999bbd04f28afe400e17c19a54
https://doi.org/10.1158/1078-0432.22482959
https://doi.org/10.1158/1078-0432.22482959
Autor:
Sergio Marchini, Giulia Siravegna, Maurizio D'Incalci, Chiara Romualdi, Marta Jaconi, Marco Adorni, Mariachiara Paderno, Martina Delle Marchette, Davide Ippolito, Fabio Landoni, Robert Fruscio, Alessia Inglesi, Tommaso Grassi, Luca Beltrame, Lara Paracchini
Patients' database
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398d25671a0931cc931e2d5e4110874d
https://doi.org/10.1158/1078-0432.22482929.v1
https://doi.org/10.1158/1078-0432.22482929.v1
Autor:
Sergio Marchini, Chiara Romualdi, Maurizio D'Incalci, Costantino Mangioni, Sergio Pecorelli, Enrico Sartori, Germana Tognon, Dionyssios Katsaros, Rodolfo Milani, Patrizia Perego, Giorgio Cattoretti, Duccio Cavalieri, Laura Zanotti, Ilaria Fuso Nerini, Mariacristina Di Marino, Lorenzo Ceppi, Luca Clivio, Luca Beltrame, Gabriele Sales, Paolo Martini, Antonella Ravaggi, Eliana Bignotti, Lara Paracchini, Robert Fruscio, Enrica Calura
Purpose: Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic diseases, with survival rate virtually unchanged for the past 30 years. EOC comprises different histotypes with molecular and clinical heterogeneity, but up till now the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c85c8fa0c63f3b3c55f1905d14968e3
https://doi.org/10.1158/1078-0432.c.6520955
https://doi.org/10.1158/1078-0432.c.6520955
Autor:
Sergio Marchini, Giulia Siravegna, Maurizio D'Incalci, Chiara Romualdi, Marta Jaconi, Marco Adorni, Mariachiara Paderno, Martina Delle Marchette, Davide Ippolito, Fabio Landoni, Robert Fruscio, Alessia Inglesi, Tommaso Grassi, Luca Beltrame, Lara Paracchini
Purpose:High-grade serous epithelial ovarian cancer (HGS-EOC) is defined by high levels of somatic copy-number alterations (SCNA) with marked spatial and temporal tumor heterogeneity. Biomarkers serving to monitor drug response and detect disease rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368db85d1734f00ea084ff298604cba2
https://doi.org/10.1158/1078-0432.c.6531041
https://doi.org/10.1158/1078-0432.c.6531041