Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lara Mellinger"'
Autor:
Robin A. Pilz, Dariush Skowronek, Lara Mellinger, Sander Bekeschus, Ute Felbor, Matthias Rath
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3993 (2023)
Cerebral cavernous malformation (CCM) is a neurovascular disease that can lead to seizures and stroke-like symptoms. The familial form is caused by a heterozygous germline mutation in either the CCM1, CCM2, or CCM3 gene. While the importance of a sec
Externí odkaz:
https://doaj.org/article/111e542fae32472c8b835f439bad95d4
Autor:
Johannes Roth, Judith Friesenhagen, Thomas Vogl, Beate Fehlhaber, Constantin von Kaisenberg, Thomas Ulas, Johanna Burgmann, Marco Ginzel, Mandy Busse, Lara Mellinger, Dorothee Viemann, Anna S. Heinemann, Sabine Pirr, Maren von Köckritz-Blickwede
Publikováno v:
The FASEB Journal. 31:1153-1164
The high susceptibility of newborn infants to sepsis is ascribed to an immaturity of the neonatal immune system, but the molecular mechanisms remain unclear. Newborn monocytes massively release the alarmins S100A8/S100A9. In adults, these are major r
Autor:
Maren von Köckritz-Blickwede, Lara Mellinger, Jennifer Schöning, Thomas Vogl, Constantin von Kaisenberg, Beate Fehlhaber, Johanna Burgmann, Friederike Reuner, Stefanie Zenker, Shirin Glander, Marie S Bickes, Johannes Roth, Katarzyna Barczyk-Kahlert, Joachim L. Schultze, Sandra Pfeifer, Thomas Ulas, Torsten G Loof, Anna S. Heinemann, Sabine Pirr, Martin Stanulla, Lena Völlger, Dorothee Viemann, Sabine Schreek, Judith Friesenhagen, Lena Fischer-Riepe
Publikováno v:
Nature immunology 18(6), 622-632 (2017). doi:10.1038/ni.3745
The high risk of neonatal death from sepsis is thought to result from impaired responses by innate immune cells; however, the clinical observation of hyperinflammatory courses of neonatal sepsis contradicts this concept. Using transcriptomic, epigene