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pro vyhledávání: '"Lara M. Tolbert"'
Autor:
et.al., Lara M. Tolbert
Publikováno v:
Pediatric Psychopharmacology: Principles and Practice.
Externí odkaz:
https://doi.org/10.1093/oso/9780195141733.003.0003
Publikováno v:
Biological Psychiatry. 54:983-993
Background Previous studies demonstrate that indirect activation of monoamine receptors by antidepressant treatment increases neurotrophic factors that activate the mitogen-activated protein kinase cascade; however, it is also possible that these mon
Publikováno v:
Journal of Neurochemistry. 81:745-757
This study examined the regulation of all known phosphodiesterase (PDE) type PDE4A, PDE4B and PDE4D splice variants in cortical neurons by cAMP signaling. Treatment with dibutyryl-cAMP (db-cAMP) caused the induction of two of the known splice variant
Publikováno v:
Molecular Pharmacology. 56:917-925
Two novel cAMP response element binding protein (CREB) splice variants were found by reverse transcription-polymerase chain reaction cloning by using mouse brain RNA as a template. One splice variant, named Delta-14, lacks 14 nucleotides at the begin
Publikováno v:
European Journal of Pharmacology. 342:123-126
Previous studies have shown that the agonist [D-Ala2, N-Me-Phe4, Gly-ol5]enkephalin (DAMGO) but not morphine induces mu-opioid receptor internalization [Arden, J.R., Segredo, V., Wang, Z., Lameh, J., Sadee, W., 1995. J. Neurochem. 65, 1636-1645]. In
Autor:
Jelveh Lameh, Lara M. Tolbert
Publikováno v:
Journal of Biological Chemistry. 271:17335-17342
The mechanism by which muscarinic receptors internalize upon agonist exposure is poorly understood. To determine the endocytic pathways responsible for muscarinic receptor internalization, we have stably transfected human embryonic kidney (HEK 293) c
Publikováno v:
Journal of neurochemistry. 74(4)
Previous evidence has suggested a role for calmodulin (CaM) in opioid receptor signaling. We demonstrate here that morphine stimulation of the μ-opioid (OP 3 ) receptor causes rapid CaM translocation to the nucleus in OP 3 -transfected human embryon
Publikováno v:
Journal of neuroscience methods. 94(2)
Basal signaling activity of the dopamine D2L (long isoform) receptor was investigated using an ecdysone-inducible mammalian expression system. Whereas basal signaling activity had been demonstrated for the D1, D2S (short isoform), D3, and D5 receptor
Autor:
Stefan R. Nahorski, Wolfgang Sadee, Andrew B. Tobin, Jelveh Lameh, Melinda S. Shockley, Lara M. Tolbert
Publikováno v:
European journal of pharmacology. 377(1)
A motif consisting of several serine residues flanked N-terminally by acidic residues occurs in the third intracellular loop of both muscarinic M1 and M3 receptors (287SerLeuThrSerSer291 and 349SerAlaSerSer352, respectively). We examined the role of
Autor:
Jelveh Lameh, Lara M. Tolbert
Publikováno v:
Journal of neurochemistry. 70(1)
We have studied the effect of an antibody against the epitope EYMPME on the internalization of the human muscarinic cholinergic receptor hm1 tagged with the epitope at the amino terminus. The antibody to the tag induces internalization of the hm1 rec