Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lara M. Kingeter"'
Autor:
Lara M. Kingeter, Xin Lin
Publikováno v:
Cellular & Molecular Immunology. 9:105-112
The C-type lectin receptors (CLRs) belong to a large family of proteins that contain a carbohydrate recognition domain (CRD) and calcium binding sites on their extracellular domains. Recent studies indicate that many CLRs, such as Dectin-1, Dectin-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb06a779199f63e63f0e799106b24c9f
https://doi.org/10.1038/cmi.2011.58
https://doi.org/10.1038/cmi.2011.58
Publikováno v:
The Journal of Immunology. 185:4520-4524
TCR-mediated activation of the transcription factor NF-κB is required for T cell proliferation, survival, and effector differentiation. Although this pathway is the subject of intense study, it is not known whether TCR signaling to NF-κB is digital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3199062170b580c00105b620d3a99fef
https://doi.org/10.4049/jimmunol.1001051
https://doi.org/10.4049/jimmunol.1001051
Autor:
Hideo Yagita, Nathan A. Franklin, Alison L. Tutt, Drew J. Roberts, Lara M. Kingeter, Timothy N. J. Bullock, Martin J. Glennie
Publikováno v:
Journal of Immunotherapy. 33:769-779
The immune response to the tumor can be enhanced by targeting costimulatory molecules on T cells. As the CD70-CD27 costimulatory axis plays an important role in the activation, survival, and differentiation of lymphocytes, we have examined the effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebed4951fff024703438cbafd03564c
https://doi.org/10.1097/cji.0b013e3181ee238f
https://doi.org/10.1097/cji.0b013e3181ee238f
Autor:
Lara M. Kingeter, Brian C. Schaefer
Publikováno v:
Cellular Signalling. 22:9-22
Malt1 is a multi-domain cytosolic signaling molecule that was originally identified as the target of recurrent translocations in a large fraction of MALT lymphomas. The product of this translocation is a chimeric protein in which the N-terminus is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9bc257cac1e780e2a4366f62b587cf
https://doi.org/10.1016/j.cellsig.2009.09.033
https://doi.org/10.1016/j.cellsig.2009.09.033
Autor:
Brian C. Schaefer, Lara M. Kingeter
Publikováno v:
The Journal of Immunology. 181:6244-6254
The cytosolic proteins protein kinase Ctheta (PKCtheta), Bcl10, and Malt1 play critical roles in TCR signaling to the transcription factor NF-kappaB. Our data confirm that CD4(+) T cells from PKCtheta, Bcl10, and Malt1 knockout mice show severe impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2401a1463dc43834793f4db36b3abfe5
https://doi.org/10.4049/jimmunol.181.9.6244
https://doi.org/10.4049/jimmunol.181.9.6244
Autor:
Brian C. Schaefer, Lara M. Kingeter
Publikováno v:
BMC Biotechnology, Vol 9, Iss 1, p 49 (2009)
BMC Biotechnology
BMC Biotechnology
Background Confocal microscopy is a widely employed methodology in cellular biology, commonly used for investigating biological organization at the cellular and sub-cellular level. Most basic confocal microscopes are equipped to cleanly discriminate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3caf274be371a21c8bd78e14189e5a7
http://www.biomedcentral.com/1472-6750/9/49
http://www.biomedcentral.com/1472-6750/9/49
Autor:
Anuj K. Kashyap, Jeremy S. Rossman, Nidhi A. Jain, Lara M. Kingeter, Brian C. Schaefer, Felicia D. Langel
Bcl10 and MALT1 are essential mediators of NF-κB activation in response to the triggering of a diverse array of transmembrane receptors, including antigen receptors. Additionally, both proteins are translocation targets in MALT lymphoma. Thus, a det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca125f73eac6635fa6c05058ac5d87e
https://europepmc.org/articles/PMC2583291/
https://europepmc.org/articles/PMC2583291/
