Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lara Kim, Brackmann"'
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Willempje Hummel-Bartenschlager, Thomas Hankeln, Christiane Kraemer, Sebastian Zahnreich, Philipp Drees, Johanna Mirsch, Claudia Spix, Maria Blettner, Heinz Schmidberger, Harald Binder, Moritz Hess, Danuta Galetzka, Federico Marini, Alicia Poplawski, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-16 (2023)
Abstract Background Differential expression analysis is usually adjusted for variation. However, most studies that examined the expression variability (EV) have used computations affected by low expression levels and did not examine healthy tissue. T
Externí odkaz:
https://doaj.org/article/9410f81dd4b5435a8409f30524056174
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Alicia Poplawski, Heike Schwarz, Willempje Hummel-Bartenschlager, Thomas Hankeln, Christiane Kraemer, Federico Marini, Sebastian Zahnreich, Iris Schmitt, Philipp Drees, Johanna Mirsch, Desiree Grabow, Heinz Schmidberger, Harald Binder, Moritz Hess, Danuta Galetzka, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-19 (2022)
Abstract Background The etiology and most risk factors for a sporadic first primary neoplasm in childhood or subsequent second primary neoplasms are still unknown. One established causal factor for therapy-associated second primary neoplasms is the e
Externí odkaz:
https://doaj.org/article/5d3e470048f04956814d2b713707f8a8
Autor:
Caine Lucas Grandt, Lara Kim Brackmann, Alicia Poplawski, Heike Schwarz, Federico Marini, Thomas Hankeln, Danuta Galetzka, Sebastian Zahnreich, Johanna Mirsch, Claudia Spix, Maria Blettner, Heinz Schmidberger, Manuela Marron
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionLong non-coding ribonucleic acids (lncRNAs) are involved in the cellular damage response following exposure to ionizing radiation as applied in radiotherapy. However, the role of lncRNAs in radiation response concerning intrinsic suscepti
Externí odkaz:
https://doaj.org/article/b0bdc83a02bf48d1aef2fa53dae0bee1
Autor:
Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Alicia Poplawski, Thomas Hankeln, Danuta Galetzka, Sebastian Zahnreich, Claudia Spix, Maria Blettner, Heinz Schmidberger, Manuela Marron
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundChildhood cancer survivors (CCS) are at particularly high risk for therapy-related late sequelae, with secondary primary neoplasms (SPN) being the most detrimental. Since there is no standardized questionnaire for retrospective assessment o
Externí odkaz:
https://doaj.org/article/cc37f11e65a14f25ab485c374d3ec6fd
Autor:
Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Danuta Galetzka, Sebastian Zahnreich, Thomas Hankeln, Markus Löbrich, Alicia Poplawski, Desiree Grabow, Maria Blettner, Heinz Schmidberger, Manuela Marron
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundImproved treatments for childhood cancer result in a growing number of long-term childhood cancer survivors (CCS). The diagnosis and the prevalence of comorbidities may, however, influence their lifestyle later in life. Nonetheless, little
Externí odkaz:
https://doaj.org/article/054fee3b7dcc4daaa9db0184535848e8
Autor:
Lara Kim Brackmann, Alicia Poplawski, Caine Lucas Grandt, Heike Schwarz, Thomas Hankeln, Steffen Rapp, Sebastian Zahnreich, Danuta Galetzka, Iris Schmitt, Christian Grad, Lukas Eckhard, Johanna Mirsch, Maria Blettner, Peter Scholz-Kreisel, Moritz Hess, Harald Binder, Heinz Schmidberger, Manuela Marron
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-13 (2020)
Abstract Background Exposure to ionizing radiation induces complex stress responses in cells, which can lead to adverse health effects such as cancer. Although a variety of studies investigated gene expression and affected pathways in human fibroblas
Externí odkaz:
https://doaj.org/article/877f92056fa24415a22d7f7ef87fe7d6
Autor:
Manuela Marron, Lara Kim Brackmann, Heike Schwarz, Willempje Hummel-Bartenschlager, Sebastian Zahnreich, Danuta Galetzka, Iris Schmitt, Christian Grad, Philipp Drees, Johannes Hopf, Johanna Mirsch, Peter Scholz-Kreisel, Peter Kaatsch, Alicia Poplawski, Moritz Hess, Harald Binder, Thomas Hankeln, Maria Blettner, Heinz Schmidberger
Publikováno v:
JMIR Research Protocols, Vol 10, Iss 11, p e32395 (2021)
BackgroundTherapy for a first primary neoplasm (FPN) in childhood with high doses of ionizing radiation is an established risk factor for second primary neoplasms (SPN). An association between exposure to low doses and childhood cancer is also sugges
Externí odkaz:
https://doaj.org/article/f53c152fb68c4b8c8bbc7f6ec6272c9a
Autor:
Manuela Marron, Lara Kim Brackmann, Pia Kuhse, Lara Christianson, Ingo Langner, Ulrike Haug, Wolfgang Ahrens
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
IntroductionInfections may play a role in the etiology of childhood cancer and immunizations may be protective because vaccinations stimulate the immune system. Observational studies reported inconsistent associations between vaccination and risk of
Externí odkaz:
https://doaj.org/article/f422a5727cde4598987b3ca5e157f59e
Autor:
Johanna Sophie Lubasch, Barbara Thumann, Jens Bucksch, Lara Kim Brackmann, Norman Wirsik, Alan Donnelly, Grainne Hayes, Katharina Nimptsch, Astrid Steinbrecher, Tobias Pischon, Johannes Brug, Wolfgang Ahrens, Antje Hebestreit
Publikováno v:
Frontiers in Sports and Active Living, Vol 2 (2020)
Objective: The study aims to investigate to what extent school- and leisure time-related factors are associated with sedentary behavior during school in German and Irish children and adolescents.Methods: The study based on a sample of 198 children an
Externí odkaz:
https://doaj.org/article/96a1a7a755184eaba027ab7a54f5d326
Autor:
Lara Kim Brackmann, Christoph Buck, Maria Adam Nyangasa, Soerge Kelm, Mohammed Sheikh, Antje Hebestreit
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Background: Aim of this study was to describe the proportion of hypertension among Zanzibari of different age-groups and to detect possible correlates of this non-communicable disease.Methods: In 2013 a cross-sectional survey was conducted in Unguja
Externí odkaz:
https://doaj.org/article/f6b50226a5e24ce08c562809630ec16a