Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lara K Abramowitz"'
Autor:
Mana Mohan Mukherjee, Michelle R. Bond, Lara K. Abramowitz, Devin Biesbrock, Carolyn C. Woodroofe, Eun Ju Kim, Rolf E. Swenson, John A. Hanover
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Metabolic chemical reporters (MCRs) provide easily accessible means to study glycans in their native environments. However, because monosaccharide precursors are shared by many glycosylation pathways, selective incorporation has been difficult to att
Externí odkaz:
https://doaj.org/article/2fae3ce760f14bde8c74518dbc6201f7
Autor:
Elizabeth O. Akinbiyi, Lara K. Abramowitz, Brianna L. Bauer, Maria S. K. Stoll, Charles L. Hoppel, Chao-Pin Hsiao, John A. Hanover, Jason A. Mears
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specifi
Externí odkaz:
https://doaj.org/article/9048e2672c6344cea6e502b9ebc484a0
Autor:
Lara K. Abramowitz, John A. Hanover
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inflammation is the immune response to harmful stimuli, including pathogens, damaged cells and toxic compounds. However, uncontrolled inflammation can be detrimental and contribute to numerous chronic inflammatory diseases, such as insulin resistance
Externí odkaz:
https://doaj.org/article/2c822c824e0a4df0b4fa5ab1c9097ec4
Autor:
Moriah Eustice, Daniel Konzman, Jeff M Reece, Salil Ghosh, Jhullian Alston, Tyler Hansen, Andy Golden, Michelle R Bond, Lara K Abramowitz, John A Hanover
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274076 (2022)
Genetic and environmental manipulations, such as dietary restriction, can improve both health span and lifespan in a wide range of organisms, including humans. Changes in nutrient intake trigger often overlapping metabolic pathways that can generate
Externí odkaz:
https://doaj.org/article/05b33ff8048849d79b4eb46114e9de85
Autor:
Daniel Konzman, Lara K. Abramowitz, Agata Steenackers, Mana Mohan Mukherjee, Hyun-Jin Na, John A. Hanover
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Cellular identity in multicellular organisms is maintained by characteristic transcriptional networks, nutrient consumption, energy production and metabolite utilization. Integrating these cell-specific programs are epigenetic modifiers, whose activi
Externí odkaz:
https://doaj.org/article/6b5c99780d7a4f2894c3a26cde53d240
Autor:
Lara K. Abramowitz, John A. Hanover, Charles L. Hoppel, Elizabeth O. Akinbiyi, Jason A. Mears, Brianna L. Bauer, Chao-Pin Hsiao, Maria S.K. Stoll
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specific impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb9ec3c0d488a07e336809b7b0177b8
https://doi.org/10.1038/s41598-021-01512-y
https://doi.org/10.1038/s41598-021-01512-y
Autor:
Lara K, Abramowitz, John A, Hanover
Publikováno v:
Frontiers in immunology. 13
Inflammation is the immune response to harmful stimuli, including pathogens, damaged cells and toxic compounds. However, uncontrolled inflammation can be detrimental and contribute to numerous chronic inflammatory diseases, such as insulin resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c15551bb142819a7671fc18f254c5ab1
https://pubmed.ncbi.nlm.nih.gov/35432339
https://pubmed.ncbi.nlm.nih.gov/35432339
Publikováno v:
PLOS Genetics. 18:e1010128
Tissue homeostasis requires a delicate balance between stem cell self-renewal, proliferation, and differentiation. Essential to this process is glycosylation, with both intra-and extra-cellular glycosylation being required for stem cell homeostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d53b25ddbb6f170eb258dcac5be3121
https://doi.org/10.1371/journal.pgen.1010128
https://doi.org/10.1371/journal.pgen.1010128
Publikováno v:
Journal of Biological Chemistry. 298:101743
Endomembrane glycosylation and cytoplasmic O-GlcNAcylation each play essential roles in nutrient sensing, and characteristic changes in glycan patterns have been described in disease states such as diabetes and cancer. These changes in glycosylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888f8678699e6ee2b0bd406aac18b20a
https://doi.org/10.1016/j.jbc.2022.101743
https://doi.org/10.1016/j.jbc.2022.101743
Autor:
Hyun-jin Na, Agata Steenackers, John A. Hanover, Daniel Konzman, Lara K. Abramowitz, Mana Mohan Mukherjee
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
Cellular identity in multicellular organisms is maintained by characteristic transcriptional networks, nutrient consumption, energy production and metabolite utilization. Integrating these cell-specific programs are epigenetic modifiers, whose activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0d21b9aadadac353f26b6db385f13b
http://europepmc.org/articles/PMC7719714
http://europepmc.org/articles/PMC7719714