Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lara J. Kohler"'
Autor:
Lara J. Kohler, Shawna C. O. Reed, Shireen A. Sarraf, David D. Arteaga, Hayley J. Newton, Craig R. Roy
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
Externí odkaz:
https://doaj.org/article/4de5bb7ff5534e40982cf99a07df7c3c
Autor:
Lara J. Kohler, Shawna R. Reed, Shireen A. Sarraf, David D. Arteaga, Hayley J. Newton, Craig R. Roy
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Coxiella burnetii replicates in an acidified lysosome-derived vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires bacterial effector proteins delivered into host cells by the Dot/Icm secretion system. Genetic and cell biolo
Externí odkaz:
https://doaj.org/article/8bb47c6794e64fadac548e48b9bdf846
Autor:
Sylvia R Trevino, Christopher P Klimko, Matthew C Reed, Michael J Aponte-Cuadrado, Melissa Hunter, Jennifer L Shoe, Joshua R Meyer, Jennifer L Dankmeyer, Sergei S Biryukov, Avery V Quirk, Kristen A Fritts, Steven J Kern, David P Fetterer, Lara J Kohler, Ronald G Toothman, Joel A Bozue, Christopher W Schellhase, Norman Kreiselmeier, Sharon P Daye, Susan L Welkos, Carl Soffler, Patricia L Worsham, David M Waag, Kei Amemiya, Christopher K Cote
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208277 (2018)
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate pathogenesis and efficacy of nov
Externí odkaz:
https://doaj.org/article/60b41a1b8810469696fef761663e8da3
Autor:
Lara J. Kohler, Craig R. Roy
Publikováno v:
Current Opinion in Microbiology. 35:36-41
Eukaryotic cells use autophagy to break down and recycle components such as aggregated proteins and damaged organelles. Research in the past decade, particularly using Salmonella enterica serovar Typhimurium as a model pathogen, has revealed that aut
Autor:
Christopher K. Cote, David P Fetterer, Matthew C. Reed, Sharon P. Daye, Sergei S. Biryukov, Steven J. Kern, Kristen A. Fritts, Kei Amemiya, Ronald G. Toothman, Melissa G. Hunter, Christopher P. Klimko, Carl Soffler, Avery V. Quirk, Susan L. Welkos, Jennifer L. Shoe, Joel A. Bozue, Sylvia R. Trevino, Norman Kreiselmeier, Lara J. Kohler, Jennifer L. Dankmeyer, Michael J. Aponte-Cuadrado, Patricia L. Worsham, Joshua R. Meyer, Christopher W. Schellhase, David M. Waag
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0208277 (2018)
PLoS ONE, Vol 13, Iss 11, p e0208277 (2018)
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate pathogenesis and efficacy of nov
Autor:
Craig R. Roy, Lara J. Kohler
Publikováno v:
Microbes and Infection. 17:766-771
Coxiella burnetii utilizes a Type IV Secretion System (T4SS) to modify host endomembrane transport systems to form a unique lysosome-derived niche called the Coxiella-containing vacuole (CCV). Although the CCV has lysosomal properties, this organelle
Autor:
Vladimir Shteyn, Craig R. Roy, Thomas J. Melia, Racquel Kim Sherwood, Karlina J. Kauffman, Karin M. Reinisch, Florian A. Horenkamp, Lara J. Kohler, Kathryn P. Krueger
Publikováno v:
Developmental Cell. 34:569-576
SummaryAutophagy is a conserved membrane transport pathway used to destroy pathogenic microbes that access the cytosol of cells. The intracellular pathogen Legionella pneumophila interferes with autophagy by delivering an effector protein, RavZ, into
Publikováno v:
Journal of applied microbiology. 124(1)
Bacterial spores resist environmental extremes and protect key spore macromolecules until more supportive conditions arise. Spores germinate upon sensing specific molecules, such as nutrients. Germination is regulated by specialized mechanisms or str
Autor:
Hayley J. Newton, Lara J. Kohler, Craig R. Roy, David D. Arteaga, Shawna C. O. Reed, Shireen A. Sarraf
Publikováno v:
mBio
mBio, Vol 7, Iss 5, p e01327-16 (2016)
mBio, Vol 7, Iss 5 (2016)
mBio, Vol 7, Iss 5, p e01327-16 (2016)
mBio, Vol 7, Iss 5 (2016)
Coxiella burnetii replicates in an acidified lysosome-derived vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires bacterial effector proteins delivered into host cells by the Dot/Icm secretion system. Genetic and cell biological ana
Autor:
Hayley J. Newton, Craig R. Roy, David D. Arteaga, Shawna C. O. Reed, Lara J. Kohler, Shireen A. Sarraf
Publikováno v:
mBio
mBio, Vol 7, Iss 4, p e01127-16 (2016)
mBio, Vol 7, Iss 4 (2016)
mBio, Vol 7, Iss 4, p e01127-16 (2016)
mBio, Vol 7, Iss 4 (2016)
Coxiella burnetii replicates in an acidified lysosome-derived vacuole. Biogenesis of the Coxiella-containing vacuole (CCV) requires bacterial effector proteins delivered into host cells by the Dot/Icm secretion system. Genetic and cell biological ana