Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lara J Bou Malhab"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11620 (2022)
Colorectal cancer is a common cancer with a poor prognosis in both males and females. The influence of bisphenol A (BPA), a widely used environmental contaminant, in colon cancer development and progression is not well identified, in spite of the fac
Externí odkaz:
https://doaj.org/article/3eac8eb574af4b50862d8f8e4c55f0ff
Autor:
Lara J. Bou Malhab, Susanne Schmidt, Christine Fagotto-Kaufmann, Emmanuelle Pion, Gilles Gadea, Pierre Roux, Francois Fagotto, Anne Debant, Dimitris P. Xirodimas
Publikováno v:
Cells, Vol 13, Iss 19, p 1625 (2024)
Mdmx (Mdm4) is established as an oncogene mainly through repression of the p53 tumour suppressor. On the other hand, anti-oncogenic functions for Mdmx have also been proposed, but the underlying regulatory pathways remain unknown. Investigations into
Externí odkaz:
https://doaj.org/article/cdc1dd4085104267b18ba727a52a1d22
Publikováno v:
Cells, Vol 13, Iss 2, p 174 (2024)
Obesity is a growing pandemic with an increasing risk of inducing different cancer types, including breast cancer. Adipose tissue is proposed to be a major player in the initiation and progression of breast cancer in obese people. However, the mechan
Externí odkaz:
https://doaj.org/article/cd12bcfdf9a248eaad96cd42c9537721
Autor:
Mohamed I. Madkour, Lara J. Bou Malhab, Wael M. Abdel-Rahman, Dana N. Abdelrahim, Maha Saber-Ayad, MoezAlIslam E. Faris
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
Aim and BackgroundA growing body of evidence supports the impact of intermittent fasting (IF) on normalizing body weight and that the interaction between body genes and environmental factors shapes human susceptibility to developing obesity. FTO gene
Externí odkaz:
https://doaj.org/article/0b4eafcd69464b68aa4520dec7529798
Publikováno v:
Current Molecular Pharmacology. 15:620-646
Abstract: The prevalence of obesity continues to increase to the extent that it became a worldwide pandemic. An accumulating body of evidence has associated obesity with the development of different types of cancer, including colorectal cancer, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b74d80bface0b3eda2873d797a16fb
https://doi.org/10.2174/1874467214666210906122054
https://doi.org/10.2174/1874467214666210906122054
Publikováno v:
Frontiers in Pharmacology. 14
Proteolysis targeting chimeras (PROTACs) are heterobifunctional small molecules that uses the proteasome ubiquitin system to target proteins of interest and promote their degradation with remarkable selectivity. Importantly, unlike conventional small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a88f1a06d52742c407dcf7cada30424
https://doi.org/10.3389/fphar.2023.1086946
https://doi.org/10.3389/fphar.2023.1086946
Autor:
Waseem El-Huneidi, Naglaa G. Shehab, Khuloud Bajbouj, Arya Vinod, Ahmed El-Serafi, Jasmin Shafarin, Lara J. Bou Malhab, Wael M. Abdel-Rahman, Eman Abu-Gharbieh
Publikováno v:
Pharmaceuticals, Vol 13, Iss 6, p 115 (2020)
Micromeria fruticosa (L.) Druce subsp. serpyllifolia (Lamiaceae) has been used widely in folk medicine to alleviate various ailments such as abdominal pains, diarrhea, colds, eye infections, heart disorders and wounds. A few reports have confirmed di
Externí odkaz:
https://doaj.org/article/46d04200953741d5b5bbf337edb06b7d
Autor:
Lara J. Bou Malhab, Khuloud Bajbouj, Naglaa G. Shehab, Salma M. Elayoty, Jithna Sinoj, Saryia Adra, Jalal Taneera, Mohamed Saleh, Wael M. Abdel-Rahman, Mohammad H. Semreen, Karem H. Alzoubi, Yasser Bustanji, Waseem El-Huneidi, Eman Abu-Gharbieh
Publikováno v:
Heliyon. :e16706
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf030032a0bc46d6d0bae2b562c43d3f
https://doi.org/10.1016/j.heliyon.2023.e16706
https://doi.org/10.1016/j.heliyon.2023.e16706
Autor:
Alya R Alnuaimi, Vidhya A Nair, Lara J Bou Malhab, Eman Abu-Gharbieh, Anu Vinod Ranade, Gianfranco Pintus, Mohamad Hamad, Hauke Busch, Jutta Kirfel, Rifat Hamoudi, Wael M Abdel-Rahman
Publikováno v:
World journal of gastrointestinal oncology. 14(9)
Colorectal cancer (CRC) is a devastating disease, mainly because of metastasis. As a result, there is a need to better understand the molecular basis of invasion and metastasis and to identify new biomarkers and therapeutic targets to aid in managing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83451c10cb4193c31bb3465cfd1fd47f
https://pubmed.ncbi.nlm.nih.gov/36187394
https://pubmed.ncbi.nlm.nih.gov/36187394
Autor:
Mohamed I. Madkour, Lara J. Bou Malhab, Wael M. Abdel-Rahman, Dana N. Abdelrahim, Maha Saber-Ayad, MoezAlIslam E. Faris
Publikováno v:
Frontiers in nutrition. 8
Aim and BackgroundA growing body of evidence supports the impact of intermittent fasting (IF) on normalizing body weight and that the interaction between body genes and environmental factors shapes human susceptibility to developing obesity. FTO gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6d3bfe1b86598f37df4bdf1b2bd92d
https://pubmed.ncbi.nlm.nih.gov/35372458
https://pubmed.ncbi.nlm.nih.gov/35372458