Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lara Heermans Winterkorn"'
Autor:
Sarah Elizabeth Albritton, Anna-Lena Kranz, Lara Heermans Winterkorn, Lena Annika Street, Sevinc Ercan
Publikováno v:
eLife, Vol 6 (2017)
In many organisms, it remains unclear how X chromosomes are specified for dosage compensation, since DNA sequence motifs shown to be important for dosage compensation complex (DCC) recruitment are themselves not X-specific. Here, we addressed this pr
Externí odkaz:
https://doaj.org/article/276b4d3270344bc9a64b3889aa8b15b1
Autor:
Max A. Seibold, Sandra Salazar, Zhanghua Chen, Soren Germer, Satria Sajuthi, Deepti Jain, Frank D. Gilliland, B. Saef, Jaehyun Joo, Esteban G. Burchard, Lara Heermans Winterkorn, Hakon Hakonarson, Marquitta J. White, Gonçalo R. Abecasis, Catherine Reeves, Ann Chen Wu, Shujie Xiao, Deborah A. Nickerson, Fred Lurmann, Scott Huntsman, Michael C. Zody, Patrick M. A. Sleiman, Celeste Eng, L. Keoki Williams, Kevin L. Keys, Eunice Y. Lee, Sam S. Oh, Hongsheng Gui, Angel C.Y. Mak, Donglei Hu, Hyun Min Kang, Rajesh Kumar, Elad Ziv, Blanca E. Himes, Fernando D. Martinez
Publikováno v:
Genetics
Genetics, vol 215, iss 3
Genetics, vol 215, iss 3
Baseline lung function is a standard diagnostic criterion used by clinicians to detect lung diseases. It is a complex trait significantly influenced by both genetics and environmental factors...
Baseline lung function, quantified as forced expir
Baseline lung function, quantified as forced expir
Autor:
Michael Wigler, Dan Levy, Adriana Muñoz, Zihua Wang, Ivan Iossifov, Seungtai Yoon, Steven Marks, Catherine Reeves, Michael Ronemus, Kith Pradhan, Kristin K. Baldwin, Peter Andrews, Lara Heermans Winterkorn, Boris Yamrom, Abba M. Krieger, Andreas Buja, Yoon-ha Lee
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Autism arises in high and low-risk families. De novo mutation contributes to autism incidence in low-risk families as there is a higher incidence in the affected of the simplex families than in their unaffected siblings. But the extent of contributio
Autor:
Max A. Seibold, Fred Lurmann, Michael C. Zody, Shujie Xiao, Catherine Reeves, Scott Huntsman, Lara Heermans Winterkorn, Sam S. Oh, B. Saef, Kevin L. Keys, Jaehyun Joo, Celeste Eng, L. Keoki Williams, Ann Chen Wu, Hakon Hakonarson, Angel C.Y. Mak, Esteban G. Burchard, Elad Ziv, Deborah A. Nickerson, Hongsheng Gui, Marquitta J. White, Fernando D. Martinez, Eunice Y. Lee, Sandra Salazar, Zhanghua Chen, Hyun Min Kang, Patrick M. A. Sleiman, Frank D. Gilliland, Donglei Hu, Blanca E. Himes, Rajesh Kumar, Satria Sajuthi, Soren Germer, Deepti Jain, Gonçalo R. Abecasis
Baseline lung function, quantified as forced expiratory volume in the first second of exhalation (FEV1), is a standard diagnostic criterion used by clinicians to identify and classify lung diseases. Using whole genome sequencing data from the Nationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c86a20667513f1e4b4a9aa2cd2aab4
Autor:
Shwetha C. Murali, Trygve E. Bakken, Rachel K. Earl, Tianyun Wang, Uday S. Evani, Kendra Hoekzema, Lara Heermans Winterkorn, Evan E. Eichler, Bradley P. Coe, Marta Byrska-Bishop, PingHsun Hsieh, Raphael Bernier, Tychele N. Turner, Hui Guo, Amy B. Wilfert, Arvis Sulovari, Michael C. Zody
Publikováno v:
Nat Genet
Autism is a highly heritable complex disorder in which de novo mutation (DNM) variation contributes significantly to risk. Using whole-genome sequencing data from 3,474 families, we investigate another source of large-effect risk variation, ultra-rar
Autor:
Marta Byrska-Bishop, Rachel K. Earl, Uday S. Evani, Kendra Hoekzema, Shwetha C. Murali, Arvis Sulovari, Tianyun Wang, Trygve E. Bakken, Bradley P. Coe, Evan E. Eichler, Tychele N. Turner, PingHsun Hsieh, Hui Guo, Lara Heermans Winterkorn, Amy B. Wilfert, Michael C. Zody, Raphael Bernier
Autism is a highly heritable, complex disorder where de novo mutation (DNM) variation contributes significantly to disease risk. Using whole-genome sequencing data from 3,474 families, we investigate another source of large-effect risk variation, ult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924b627cd0fde33540f0c110516e051c
https://doi.org/10.1101/2020.02.10.932327
https://doi.org/10.1101/2020.02.10.932327
Autor:
Lena Annika, Street, Ana Karina, Morao, Lara Heermans, Winterkorn, Chen-Yu, Jiao, Sarah Elizabeth, Albritton, Mohammed, Sadic, Maxwell, Kramer, Sevinç, Ercan
Publikováno v:
Genetics
Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In Caenorhabditis elegans, a specialized condensin, which forms the core of the dos
Autor:
Lara Heermans Winterkorn, Sarah Elizabeth Albritton, Ana Karina Morao, Sevinc Ercan, Chen-Yu Jiao, Mohammed Sadic, Maxwell Kramer, Lena Annika Street
Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In C. elegans,, a specialized condensin, which forms the core of the dosage compens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c83aa24d8fa0ec36459e4a445ce4c2
https://doi.org/10.1101/516419
https://doi.org/10.1101/516419
Autor:
Lena Annika Street, Lara Heermans Winterkorn, Sarah Elizabeth Albritton, Sevinc Ercan, Anna Lena Kranz
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
In many organisms, it remains unclear how X chromosomes are specified for dosage compensation, since DNA sequence motifs shown to be important for dosage compensation complex (DCC) recruitment are themselves not X-specific. Here, we addressed this pr