Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lara Gales"'
Autor:
Céline Jaillard, Farah Ouechtati, Emmanuelle Clérin, Géraldine Millet-Puel, Mariangela Corsi, Najate Aït-Ali, Frédéric Blond, Quentin Chevy, Lara Gales, Mélissa Farinelli, Deniz Dalkara, José-Alain Sahel, Jean-Charles Portais, Jean-Christophe Poncer, Thierry Léveillard
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102198- (2021)
The nucleoredoxin gene NXNL2 encodes for two products through alternative splicing, rod-derived cone viability factor-2 (RdCVF2) that mediates neuronal survival and the thioredoxin-related protein (RdCVF2L), an enzyme that regulates the phosphorylati
Externí odkaz:
https://doaj.org/article/ad3fc9da614f44d681064fa163f7b7dd
Autor:
Jason Ziveri, Fabiola Tros, Ida Chiara Guerrera, Cerina Chhuon, Mathilde Audry, Marion Dupuis, Monique Barel, Sarantis Korniotis, Simon Fillatreau, Lara Gales, Edern Cahoreau, Alain Charbit
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The enzyme fructose-bisphosphate aldolase (FBA) plays central roles in glycolysis and gluconeogenesis. Here, Ziveri et al. show that FBA of the pathogen Francisella novicida acts, in addition, as a transcriptional regulator and is important for bacte
Externí odkaz:
https://doaj.org/article/8dc1a270813149de956d15a4be2abb18
Autor:
Cécilia Bergès, Edern Cahoreau, Pierre Millard, Brice Enjalbert, Mickael Dinclaux, Maud Heuillet, Hanna Kulyk, Lara Gales, Noémie Butin, Maxime Chazalviel, Tony Palama, Matthieu Guionnet, Sergueï Sokol, Lindsay Peyriga, Floriant Bellvert, Stéphanie Heux, Jean-Charles Portais
Publikováno v:
Metabolites, Vol 11, Iss 5, p 271 (2021)
We have developed a robust workflow to measure high-resolution fluxotypes (metabolic flux phenotypes) for large strain libraries under fully controlled growth conditions. This was achieved by optimizing and automating the whole high-throughput fluxom
Externí odkaz:
https://doaj.org/article/c761429155da4cd3aca1f0b21e6492dc
Autor:
Joran Villaret-Cazadamont, Nathalie Poupin, Anthony Tournadre, Aurélie Batut, Lara Gales, Daniel Zalko, Nicolas J. Cabaton, Floriant Bellvert, Justine Bertrand-Michel
Publikováno v:
Metabolites, Vol 10, Iss 12, p 490 (2020)
The authors wish to make the following comment to the paper [...]
Externí odkaz:
https://doaj.org/article/9a25db7f51ba4fb49d819005a6f563b2
Autor:
Joran Villaret-Cazadamont, Nathalie Poupin, Anthony Tournadre, Aurélie Batut, Lara Gales, Daniel Zalko, Nicolas J. Cabaton, Floriant Bellvert, Justine Bertrand-Michel
Publikováno v:
Metabolites, Vol 10, Iss 9, p 338 (2020)
The functional understanding of metabolic changes requires both a significant investigation into metabolic pathways, as enabled by global metabolomics and lipidomics approaches, and the comprehensive and accurate exploration of specific key pathways.
Externí odkaz:
https://doaj.org/article/5bd9ab41d5dd4c7489d50c98ef7bc21f
Autor:
Jean-Emmanuel Sarry, Christian Récher, Martin Carroll, Gwenn Danet-Desnoyers, Mary Selak, François Vergez, Jean-Charles Portais, Barbara H. Garmy-Susini, François Delhommeau, Lara Gales, Tony Palama, Pierre Hirsch, Yara Barreira, Olivier Duchamp, Yves Collette, Emmanuel Griessinger, Rémy Castellano, Camille Montersino, Laetitia K. Linares, Jason Iacovoni, Laurent Vallar, Tony Kaoma, Suzanne Tavitian, Audrey Sarry, Nizar Serhan, Marion David, Nicolas Broin, Stéphanie Cassant-Sourdy, Marie-Laure Nicolau-Travers, Virginie Féliu, Héléna Boutzen, Clément Larrue, Sarah Scotland, Marine Fraisse, Lucille Stuani, Mayumi Sugita, Claudie Bosc, Robin Perry, Mohsen Hosseini, Nesrine Aroua, Fabienne de Toni, Estelle Saland, Thomas Farge
HIGH CD36 gene signature generated from upregulated genes in AML patients that express the most CD36 mRNA compared to that of the lowest expression of CD36 in TCGA cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4551720b39c2c7a62933d1c7a214327a
https://doi.org/10.1158/2159-8290.22532159
https://doi.org/10.1158/2159-8290.22532159
Autor:
Jean-Emmanuel Sarry, Christian Récher, Martin Carroll, Gwenn Danet-Desnoyers, Mary Selak, François Vergez, Jean-Charles Portais, Barbara H. Garmy-Susini, François Delhommeau, Lara Gales, Tony Palama, Pierre Hirsch, Yara Barreira, Olivier Duchamp, Yves Collette, Emmanuel Griessinger, Rémy Castellano, Camille Montersino, Laetitia K. Linares, Jason Iacovoni, Laurent Vallar, Tony Kaoma, Suzanne Tavitian, Audrey Sarry, Nizar Serhan, Marion David, Nicolas Broin, Stéphanie Cassant-Sourdy, Marie-Laure Nicolau-Travers, Virginie Féliu, Héléna Boutzen, Clément Larrue, Sarah Scotland, Marine Fraisse, Lucille Stuani, Mayumi Sugita, Claudie Bosc, Robin Perry, Mohsen Hosseini, Nesrine Aroua, Fabienne de Toni, Estelle Saland, Thomas Farge
Supplementary Methods. Supplementary Figure S1. Clinical distributions of AML patients from TUH and 3 independent patient cohorts. Supplementary Figure S2. In vivo treatment with 60 mg/kg/d of cytarabine (AraC) given daily for 5 days induces a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2f0e8478dfe809f6b2b2680407008f
https://doi.org/10.1158/2159-8290.22532177.v1
https://doi.org/10.1158/2159-8290.22532177.v1
Autor:
Guillaume Cognet, Lucille Stuani, Thomas Farge, Mathilde Gotanègre, Maud Heuillet, Lara Gales, Amandine Rocher, Nina Lager-Lachaud, Claudie Bosc, Marie Sabatier, Estelle Saland, Ambrine Sahal, Laura Poillet-Perez, Francois Vergez, Véronique de Mas, Christian Récher, Jean-Charles Portais, Floriant Bellvert, Jean-Emmanuel Sarry
Background Metabolic adaptation is a hallmark of cancer including acute myeloid leukemia (AML). Tumor microenvironment is also described as an essential support of leukemic metabolism. We explored how systemic and tissue metabolism was rewired in leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24799f8e6ef65cef1a6407782d4d4b4d
https://hal.science/hal-03884825/document
https://hal.science/hal-03884825/document
Autor:
Emmanuelle Clérin, Frédéric Blond, Mariangela Corsi, Farah Ouechtati, Jean-Charles Portais, Géraldine Millet-Puel, Thierry Léveillard, Mélissa Farinelli, Lara Gales, Deniz Dalkara, Céline Jaillard, Jean Christophe Poncer, José-Alain Sahel, Najate Aït-Ali, Quentin Chevy
Publikováno v:
Redox Biology, Vol 48, Iss, Pp 102198-(2021)
Redox Biology
Redox Biology, Elsevier, 2021, 48, pp.102198. ⟨10.1016/j.redox.2021.102198⟩
Redox Biology, 2021, 48, pp.102198. ⟨10.1016/j.redox.2021.102198⟩
Redox Biology
Redox Biology, Elsevier, 2021, 48, pp.102198. ⟨10.1016/j.redox.2021.102198⟩
Redox Biology, 2021, 48, pp.102198. ⟨10.1016/j.redox.2021.102198⟩
International audience; The nucleoredoxin gene NXNL2 encodes for two products through alternative splicing, rod-derived cone viability factor-2 (RdCVF2) that mediates neuronal survival and the thioredoxin-related protein (RdCVF2L), an enzyme that reg
Autor:
Lara Gales, Camille Montersino, Marc Conti, Pierre Bories, Courtney D. DiNardo, Brandon Nicolay, Fabien Jourdan, Nicolas Broin, Mohsen Hosseini, Guillaume Cognet, Yves Gibon, Marie Sabatier, Tony Kaoma, Marina Konopleva, Lucille Stuani, Mathilde Gotanègre, Christian Recher, Laurent Fernando, Vera Pancaldi, Nathalie Poupin, Estelle Saland, Jean-Emmanuel Sarry, Joseph R. Marszalek, Andrei Turtoi, Thomas Farge, Feng Wang, Yves Collette, Laurent Le Cam, Madi Y. Cissé, Cédric Cassan, Alexis Hucteau, Claudie Bosc, Natalia Baran, Sebastien Ronseaux, Aliki Zavoriti, François Fenaille, Florence Castelli, Laetitia K. Linares, Evgenia Turtoi, Emeline Chu-Van, Martin Carroll, Pierre-Luc Mouchel, Mary A. Selak, Guillaume Cazals, Emeline Boet, Rémy Castellano, Floriant Bellvert, Norbert Vey, Clément Larrue, Koichi Takahashi, Ambrine Sahal, Sylvain Loric, Jean-Charles Portais
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20200924⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20200924⟩
The Journal of Experimental Medicine
Stuani et al. demonstrate that IDH mutant AML cells display an enhanced mitochondrial phenotype, which is not reversed by IDH mutant inhibitors. This study provides a scientific rationale for combinatory mitochondrial-targeted therapies to treat IDH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfb2b30f8b948c067d643d1119fbb0e
https://amu.hal.science/hal-03563454/file/jStuani_em_20200924.pdf
https://amu.hal.science/hal-03563454/file/jStuani_em_20200924.pdf