Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Lara E Sucheston"'
Autor:
Song Yao, Chi-Chen Hong, Edward A Ruiz-Narváez, Sharon S Evans, Qianqian Zhu, Beverly A Schaefer, Li Yan, Marie V Coignet, Kathryn L Lunetta, Lara E Sucheston-Campbell, Kelvin Lee, Elisa V Bandera, Melissa A Troester, Lynn Rosenberg, Julie R Palmer, Andrew F Olshan, Christine B Ambrosone
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007368 (2018)
Selection pressure due to exposure to infectious pathogens endemic to Africa may explain distinct genetic variations in immune response genes. However, the impact of those genetic variations on human immunity remains understudied, especially within t
Externí odkaz:
https://doaj.org/article/ed9ff7ccc3e9420880e0d17486e32a93
Autor:
Ellen L Goode, Melissa DeRycke, Kimberly R Kalli, Ann L Oberg, Julie M Cunningham, Matthew J Maurer, Brooke L Fridley, Sebastian M Armasu, Daniel J Serie, Priya Ramar, Krista Goergen, Robert A Vierkant, David N Rider, Hugues Sicotte, Chen Wang, Boris Winterhoff, Catherine M Phelan, Joellen M Schildkraut, Rachel P Weber, Ed Iversen, Andrew Berchuck, Rebecca Sutphen, Michael J Birrer, Shalaka Hampras, Leah Preus, Simon A Gayther, Susan J Ramus, Nicolas Wentzensen, Hannah P Yang, Montserrat Garcia-Closas, Honglin Song, Jonathan Tyrer, Paul P D Pharoah, Gottfried Konecny, Thomas A Sellers, Roberta B Ness, Lara E Sucheston, Kunle Odunsi, Lynn C Hartmann, Kirsten B Moysich, Keith L Knutson
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53903 (2013)
Although ovarian cancer is the most lethal of gynecologic malignancies, wide variation in outcome following conventional therapy continues to exist. The presence of tumor-infiltrating regulatory T cells (Tregs) has a role in outcome of this disease,
Externí odkaz:
https://doaj.org/article/2a05f1d2af3f48b587874e2042946aa9
Autor:
Lara E Sucheston, Jeannette T Bensen, Zongli Xu, Prashant K Singh, Leah Preus, James L Mohler, L Joseph Su, Elizabeth T H Fontham, Bernardo Ruiz, Gary J Smith, Jack A Taylor
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e30950 (2012)
Family history and African-American race are important risk factors for both prostate cancer (CaP) incidence and aggressiveness. When studying complex diseases such as CaP that have a heritable component, chances of finding true disease susceptibilit
Externí odkaz:
https://doaj.org/article/0f45a60efb1241638f020c871b852016
Autor:
Song Yao, Lara E Sucheston, Amy E Millen, Candace S Johnson, Donald L Trump, Mary K Nesline, Warren Davis, Chi-Chen Hong, Susan E McCann, Helena Hwang, Swati Kulkarni, Stephen B Edge, Tracey L O'Connor, Christine B Ambrosone
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17251 (2011)
Results from epidemiologic studies on the relationship between vitamin D and breast cancer risk are inconclusive. It is possible that vitamin D may be effective in reducing risk only of specific subtypes due to disease heterogeneity.In case-control a
Externí odkaz:
https://doaj.org/article/c7389d85949b4cf396f7fba01015550d
Autor:
Song Yao, Lara E Sucheston, Shannon L Smiley, Warren Davis, Jeffrey M Conroy, Norma J Nowak, Christine B Ambrosone, Philip L McCarthy, Theresa Hahn
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25940 (2011)
Bone mineral density (BMD) loss commonly occurs after hematopoietic cell transplantation (HCT). Hypothesizing that genetic variants may influence post-HCT BMD loss, we conducted a prospective study to examine the associations of single nucleotide pol
Externí odkaz:
https://doaj.org/article/6eb332c3a6c643a8ba8812c753207ab9
Autor:
Ali Foroughi pour, Maciej Pietrzak, Lara E. Sucheston-Campbell, Ezgi Karaesmen, Lori A. Dalton, Grzegorz A. Rempała
Publikováno v:
BMC Medical Genomics, Vol 13, Iss S9, Pp 1-22 (2020)
Abstract Background Developing binary classification rules based on SNP observations has been a major challenge for many modern bioinformatics applications, e.g., predicting risk of future disease events in complex conditions such as cancer. Small-sa
Externí odkaz:
https://doaj.org/article/d6da352384784b5f8411ddfc07adac08
Autor:
Junke Wang, Alyssa I. Clay-Gilmour, Ezgi Karaesmen, Abbas Rizvi, Qianqian Zhu, Li Yan, Leah Preus, Song Liu, Yiwen Wang, Elizabeth Griffiths, Daniel O. Stram, Loreall Pooler, Xin Sheng, Christopher Haiman, David Van Den Berg, Amy Webb, Guy Brock, Stephen Spellman, Marcelo Pasquini, Philip McCarthy, James Allan, Friedrich Stölzel, Kenan Onel, Theresa Hahn, Lara E. Sucheston-Campbell
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The role of common genetic variation in susceptibility to acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS), a group of rare clonal hematologic disorders characterized by dysplastic hematopoiesis and high mortality, remains unclear. We
Externí odkaz:
https://doaj.org/article/fa262d77b31b4da591c8a81a451b985b
Autor:
Ezgi Karaesmen, Theresa Hahn, Alexander James Dile, Abbas A. Rizvi, Junke Wang, Tao Wang, Michael D. Haagenson, Leah Preus, Qianqian Zhu, Qian Liu, Li Yan, Song Liu, Christopher A. Haiman, Daniel Stram, Loreall Pooler, Xin Sheng, David Van Den Berg, Guy Brock, Amy Webb, Philip L. McCarthy, Marcelo C. Pasquini, Stephen R. Spellman, Stephanie J. Lee, Sophie Paczesny, Lara E. Sucheston-Campbell
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2512-2524 (2019)
Abstract: Graft-versus-host disease (GVHD) and infections are the 2 main causes of death without relapse after allogeneic hematopoietic cell transplantation (HCT). Elevated soluble serum simulation-2 (sST2), the product of IL1RL1 in plasma/serum post
Externí odkaz:
https://doaj.org/article/b5a5fbd3681545f893974314a2ebe8d0
Autor:
Hancong Tang, Theresa Hahn, Ezgi Karaesmen, Abbas A. Rizvi, Junke Wang, Sophie Paczesny, Tao Wang, Leah Preus, Qianqian Zhu, Yiwen Wang, Christopher A. Haiman, Daniel Stram, Loreall Pooler, Xin Sheng, David Van Den Berg, Guy Brock, Amy Webb, Marcelo C. Pasquini, Philip L. McCarthy, Stephen R. Spellman, Lara E. Sucheston-Campbell
Publikováno v:
Blood Advances, Vol 3, Iss 15, Pp 2337-2341 (2019)
Externí odkaz:
https://doaj.org/article/7f14fab0fe83453996f2b88f7b3b5f17
Autor:
Manjunath Siddappa, Shahid Hussain, Sajad A. Wani, Jason White, Hancong Tang, Jaimie S. Gray, Hedieh Jafari, Hsu-Chang Wu, Mark D. Long, Isra Elhussin, Balasubramanyam Karanam, Honghe Wang, Rebecca Morgan, Gary Hardiman, Isaacson B. Adelani, Solomon O. Rotimi, Adam R. Murphy, Larisa Nonn, Melissa B. Davis, Rick A. Kittles, Chanita Hughes Halbert, Lara E. Sucheston-Campbell, Clayton Yates, Moray J. Campbell
Publikováno v:
Siddappa, M, Hussain, S, Wani, S A, White, J, Tang, H, Gray, J S, Jafari, H, Wu, H-C, Long, M D, Elhussin, I, Karanam, B, Wang, H, Morgan, R, Hardiman, G, Adelani, I B, Rotimi, S O, Murphy, A R, Nonn, L, Davis, M B, Kittles, R A, Hughes Halbert, C, Sucheston-Campbell, L E, Yates, C & Campbell, M J 2023, ' African American prostate cancer displays quantitatively distinct vitamin D receptor cistrome-transcriptome relationships regulated by BAZ1A ', Cancer Research Communications, vol. 3, no. 4, pp. 621-639 . https://doi.org/10.1158/2767-9764.crc-22-0389
African American (AA) prostate cancer associates with vitamin D3 deficiency, but vitamin D receptor (VDR) genomic actions have not been investigated in this context. We undertook VDR proteogenomic analyses in European American (EA) and AA prostate ce