Immunotherapy of pediatric brain tumor patients should include an immunoprevention strategy: a medical hypothesis paper

Autor: Neil Hoa, Martin R. Jadus, Elizabeth W. Newcomb, Lisheng Ge, Lara Driggers, Jian-Gang Zhang

Publikováno v: Driggers, Lara; Zhang, Jian-Gang; Newcomb, Elizabeth W.; Ge, Lisheng; Hoa, Neil; & Jadus, Martin R.(2010). Immunotherapy of pediatric brain tumor patients should include an immunoprevention strategy: a medical hypothesis paper. Journal of Neuro-Oncology, 97(2), pp 159-169. doi: 10.1007/s11060-009-0016-0. Retrieved from: http://www.escholarship.org/uc/item/1nr7x6kb
Journal of Neuro-Oncology

Adults diagnosed with Glioblastoma multiforme (GBM) are frequently faced with a 7% chance of surviving 2 years compared with pediatric patients with GBM who have a 26% survival rate. Our recent screen of possible glioma-associated antigen precursor p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0518affd56f80c31fc5c20c98182290
https://doi.org/10.1007/s11060-009-0016-0

Macrophage colony stimulating factor: not just for macrophages anymore! A gateway into complex biologies

Autor: Christina Delgado, Jian Gang Zhang, Lara Driggers, Neil Hoa, Edward W.B. Jeffes, Martin R. Jadus, Kirston Koths, Michael P. Myers, Christopher C. Williams, H. Terry Wepsic, Ramon Sanchez, Thomas Douglass, Qinhong Dan

Publikováno v: International immunopharmacology. 8(10)

Macrophage colony stimulating factor (M-CSF, also called colony stimulating factor-1) has traditionally been viewed as a growth/differentiation factor for monocytes, macrophages, and some female-specific tumors. As a result of alternative mRNA splici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24eb3e4afdf7f44d4646f7bc6a8be25
https://pubmed.ncbi.nlm.nih.gov/18687298

Molecular Mechanisms of Paraptosis Induction: Implications for a Non-Genetically Modified Tumor Vaccine

Autor: Christina Delgado, Neil Hoa, Lisheng Ge, Martin R. Jadus, Jimmy T. H. Pham, Thomas Douglass, Lara Driggers, Nirav Bhakta, Jian Gang Zhang, Gerald Vandeusen, Michael P. Myers, Linda L. Callahan

Publikováno v: PLoS ONE
Hoa, Neil; Myers, Michael P.; Douglass, Thomas G.; Zhang, Jian Gang; Delgado, Christina; Driggers, Lara; et al.(2009). Molecular Mechanisms of Paraptosis Induction: Implications for a Non-Genetically Modified Tumor Vaccine. PLoS One, 4(2), e4631. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9rz4r3nb
PLoS ONE, Vol 4, Iss 2, p e4631 (2009)

Paraptosis is the programmed cell death pathway that leads to cellular necrosis. Previously, rodent and human monocytes/macrophages killed glioma cells bearing the membrane macrophage colony stimulating factor (mM-CSF) through paraptosis, but the mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3b5713127d97c342db85a88a5a3482
https://doi.org/10.1371/journal.pone.0004631

Cancer Researcher Biographical Sketches and Research Summaries

Autor: Toh, Kong Ai, Tsai, Gao Shi

This new book compiles biographical sketches of top professionals in the field of cancer research, as well as research summaries from a number of different focuses in this important field.