Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lara Cheslow"'
Autor:
Lara Cheslow, Matthew Byrne, Jessica S. Kopenhaver, Lorraine Iacovitti, Richard J. Smeyne, Adam E. Snook, Scott A. Waldman
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Mitochondrial dysfunction and reactive oxygen species (ROS) accumulation within the substantia nigra pars compacta (SNpc) are central drivers of dopaminergic (DA) neuron death in Parkinson’s disease (PD). Guanylyl cyclases and their second
Externí odkaz:
https://doaj.org/article/875aeffe76714a2baa47bb9bad8684dd
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 398 (2024)
Neurological disorders are the leading cause of cognitive and physical disability worldwide, affecting 15% of the global population. Due to the demographics of aging, the prevalence of neurological disorders, including neurodegenerative diseases, wil
Externí odkaz:
https://doaj.org/article/5d3afeb69b3a41b5b70f8de86e180c2d
Publikováno v:
Biomark Med
Parkinson’s disease (PD) is a highly prevalent and irreversible neurodegenerative disorder that is typically diagnosed in an advanced stage. Currently, there are no approved biomarkers that reliably identify PD patients before they have undergone e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b75404f6d7b9efd7a3c962ce072fff
https://pubmed.ncbi.nlm.nih.gov/33988462
https://pubmed.ncbi.nlm.nih.gov/33988462
Autor:
Lara Cheslow, E. John Wherry, Molly E. Church, Richa Kapoor, M Andres Blanco, Jorge I. Alvarez, Miles C Miller, James Gesualdi, Mohamed S. Abdel-Hakeem, Naïl Benallegue, Alexis M. Crockett, Hania Kebir, Cen Li
Publikováno v:
Brain
The concerted actions of the CNS and the immune system are essential to coordinating the outcome of neuroinflammatory responses. Yet, the precise mechanisms involved in this crosstalk and their contribution to the pathophysiology of neuroinflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06256803dc1472e79d020f107d1ddf15
https://pubmed.ncbi.nlm.nih.gov/33723591
https://pubmed.ncbi.nlm.nih.gov/33723591
Autor:
Jorge I. Alvarez, Lara Cheslow
Publikováno v:
Current Opinion in Pharmacology. 26:39-46
The blood-brain barrier (BBB) is comprised of unique endothelial cells (ECs) that regulate the delicate central nervous system (CNS) microenvironment. During development, vasculature sprouts from the perivascular neural plexus and penetrates the CNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4866529ff0d35238bdec906b696c75
https://doi.org/10.1016/j.coph.2015.09.010
https://doi.org/10.1016/j.coph.2015.09.010
Autor:
Alexandre Prat, Lara Cheslow, Jorge I. Alvarez, Marc Chabarati, Hania Kebir, Catherine Larochelle
Publikováno v:
Annals of Clinical and Translational Neurology
Leukocyte transmigration into the central nervous system promotes multiple sclerosis pathogenesis, yet ambiguity remains regarding the mechanisms controlling the migration of distinct immune cell subsets. Using in vitro, ex vivo and postmortem human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d2436b461e76452f657183cd174102
https://doi.org/10.1002/acn3.255
https://doi.org/10.1002/acn3.255