Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Lara A Doyle-Meyers"'
Autor:
Alyssa C Fears, Brandon J Beddingfield, Nicole R Chirichella, Nadia Slisarenko, Stephanie Z Killeen, Rachel K Redmann, Kelly Goff, Skye Spencer, Breanna Picou, Nadia Golden, Cecily C Midkiff, Duane J Bush, Luis M Branco, Matthew L Boisen, Hongmei Gao, David C Montefiori, Robert V Blair, Lara A Doyle-Meyers, Kasi Russell-Lodrigue, Nicholas J Maness, Chad J Roy
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010618 (2022)
The novel coronavirus SARS-CoV-2 emerged in late 2019, rapidly reached pandemic status, and has maintained global ubiquity through the emergence of variants of concern. Efforts to develop animal models have mostly fallen short of recapitulating sever
Externí odkaz:
https://doaj.org/article/520e4f07330948dfb9dec099171ac336
Autor:
Scott P Lawrence, Samra E Elser, Workineh Torben, Robert V Blair, Bapi Pahar, Pyone P Aye, Faith Schiro, Dawn Szeltner, Lara A Doyle-Meyers, Beth S Haggarty, Andrea P O Jordan, Josephine Romano, George J Leslie, Xavier Alvarez, David H O'Connor, Roger W Wiseman, Christine M Fennessey, Yuan Li, Michael Piatak, Jeffrey D Lifson, Celia C LaBranche, Andrew A Lackner, Brandon F Keele, Nicholas J Maness, Mark Marsh, James A Hoxie
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010507 (2022)
The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved Tyr-based trafficking signal that mediates both clathrin-dependent endocytosis and polarized sorting. Despite extensive analysis, the role of these functions in vi
Externí odkaz:
https://doaj.org/article/d548a853acc4469fa6a4e1326a82b9a7
Autor:
Alexandra Melton, Lara A Doyle-Meyers, Robert V Blair, Cecily Midkiff, Hunter J Melton, Kasi Russell-Lodrigue, Pyone P Aye, Faith Schiro, Marissa Fahlberg, Dawn Szeltner, Skye Spencer, Brandon J Beddingfield, Kelly Goff, Nadia Golden, Toni Penney, Breanna Picou, Krystle Hensley, Kristin E Chandler, Jessica A Plante, Kenneth S Plante, Scott C Weaver, Chad J Roy, James A Hoxie, Hongmei Gao, David C Montefiori, Joseph L Mankowski, Rudolf P Bohm, Jay Rappaport, Nicholas J Maness
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010162 (2021)
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithf
Externí odkaz:
https://doaj.org/article/a4d62fa7ec5b4fcc9a46c16a5466b091
Autor:
Monica E Embers, Nicole R Hasenkampf, Mary B Jacobs, Amanda C Tardo, Lara A Doyle-Meyers, Mario T Philipp, Emir Hodzic
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189071 (2017)
The efficacy and accepted regimen of antibiotic treatment for Lyme disease has been a point of significant contention among physicians and patients. While experimental studies in animals have offered evidence of post-treatment persistence of Borrelia
Externí odkaz:
https://doaj.org/article/5dc59edc4c684b31a0770a258f675b9b
Autor:
Alexandra Melton, Lori A. Rowe, Toni Penney, Clara Krzykwa, Kelly Goff, Sarah E. Scheuermann, Hunter J. Melton, Kelsey Williams, Nadia Golden, Kristyn Moore Green, Brandon Smith, Kasi Russell-Lodrigue, Jason P. Dufour, Lara A. Doyle-Meyers, Faith Schiro, Pyone P. Aye, Jeffery D. Lifson, Brandon J. Beddingfield, Robert V. Blair, Rudolf P. Bohm, Jay K. Kolls, Jay Rappaport, James A. Hoxie, Nicholas J. Maness
Publikováno v:
Viruses, Vol 16, Iss 7, p 1173 (2024)
The effects of immunodeficiency associated with chronic HIV infection on COVID-19 disease and viral persistence have not been directly addressed in a controlled setting. In this pilot study, we exposed two pigtail macaques (PTMs) chronically infected
Externí odkaz:
https://doaj.org/article/6540d9832a1c4780aadcbb2a30855213
Autor:
Brandon J. Beddingfield, Nicholas J. Maness, Skye Spencer, Jay Rappaport, Pyone Pyone Aye, Kasi Russell-Lodrigue, Lara A. Doyle-Meyers, Robert V. Blair, HongMei Gao, David Montefiori, Chad J. Roy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSARS-CoV-2 is a respiratory pathogen currently causing a worldwide pandemic, with resulting pathology of differing severity in humans, from mild illness to severe disease and death. The rhesus macaque model of COVID-19 was utilized to eva
Externí odkaz:
https://doaj.org/article/3772dde98cab499297a36830dbf4d85e
Autor:
Alyssa C. Fears, Edith M. Walker, Nicole Chirichella, Nadia Slisarenko, Kristen M. Merino, Nadia Golden, Breanna Picou, Skye Spencer, Kasi E. Russell-Lodrigue, Lara A. Doyle-Meyers, Robert V. Blair, Brandon J. Beddingfield, Nicholas J. Maness, Chad J. Roy, Namita Rout
Publikováno v:
Communications Biology. 5
Although most SARS-CoV-2 infections are mild, some patients develop systemic inflammation and progress to acute respiratory distress syndrome (ARDS). However, the cellular mechanisms underlying this spectrum of disease remain unclear. γδT cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3922ccc91b7a5e9df8b3a102957b23
https://doi.org/10.1038/s42003-022-04310-y
https://doi.org/10.1038/s42003-022-04310-y
Autor:
Kasi E. Russell-Lodrigue, Monica N. Shroyer, Lara A. Doyle-Meyers, Margaret H. Gilbert, Sarah Kezar
Publikováno v:
Journal of Medical Primatology. 51:45-48
Tracheal disruption is a previously unreported complication of nonhuman primate social trauma. Two cases were identified in rhesus macaques with subcutaneous emphysema. These cases resolved with medical management and demonstrate that the combined us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386d42edb6933db924b978c21275213d
https://doi.org/10.1111/jmp.12550
https://doi.org/10.1111/jmp.12550
Autor:
Xiaolei Wang, Eunice Vincent, Summer Siddiqui, Katherine Turnbull, Hong Lu, Robert Blair, Xueling Wu, Meagan Watkins, Widade Ziani, Jiasheng Shao, Lara A. Doyle-Meyers, Kasi E. Russell-Lodrigue, Rudolf P. Bohm, Ronald S. Veazey, Huanbin Xu
Publikováno v:
Nature Communications. 13
Early antiretroviral therapy (ART) in HIV-infected infants generally fails to achieve a sustained state of ART-free virologic remission, leading to rapid viral rebound, even after years of analytical treatment interruption. Our studies showed that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5f2c8429bf094c3c620db61b5fcd76
https://doi.org/10.1038/s41467-022-32554-z
https://doi.org/10.1038/s41467-022-32554-z
Autor:
Shankar Subramaniam, David Veesler, Lauren Carter, David Novack, Claire Sydeman, Jane Fontenot, Douglas E. Ferrell, Galit Alter, Robbert van der Most, Robert L. Coffman, Elizabeth Kepl, Mary Jane Navarro, Alexander G. White, Ching-Lin Hsieh, Kenneth S. Plante, Francois Villinger, Katharina Röltgen, Prabhu S. Arunachalam, Alexandra C. Walls, Jason S. McLellan, Lisa Shirreff, Rino Rappuoli, Sally Shin, Venkata Viswanadh Edara, Jessica A. Plante, Brooke Fiala, Stephanie Fischinger, Chunfeng Li, Caroline Atyeo, Matthew J. Gorman, Chad J. Roy, Scott D. Boyd, Bali Pulendran, Kasi E. Russell-Lodrigue, Skye Spencer, Xiaoying Shen, Shakti Gupta, Derek T. O'Hagan, Pyone P. Aye, Meera Trisal, Neil P. King, JoAnne L. Flynn, Nadia A. Golden, Marcos C. Miranda, Michael E. P. Murphy, John C. Kraft, Mehul S. Suthar, Lilin Lai, Jason Dufour, Rudolph Bohm, Deleah Pettie, Lara A. Doyle-Meyers, David C. Montefiori, Christopher Monjure, Kenneth A. Rogers, Samuel Wrenn, Harry Kleanthous, Nicholas J. Maness, Jay Rappaport, Alex Lee Zhu, Natalie Brunette
Publikováno v:
Nature. 594:253-258
The development of a portfolio of COVID-19 vaccines to vaccinate the global population remains an urgent public health imperative1. Here we demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442cf7639520da9f4126cb4a6dcc72fb
https://doi.org/10.1038/s41586-021-03530-2
https://doi.org/10.1038/s41586-021-03530-2