Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Lara, Leoni"'
Autor:
Jason P. Meier, Hannah J. Zhang, Richard Freifelder, Mohammed Bhuiyan, Phillip Selman, Megan Mendez, Pavithra H. A. Kankanamalage, Thomas Brossard, Antonino Pusateri, Hsiu-Ming Tsai, Lara Leoni, Sagada Penano, Kaustab Ghosh, Brittany A. Broder, Erica Markiewicz, Amy Renne, Walter Stadler, Ralph Weichselbaum, Jerry Nolen, Chien-Min Kao, Satish K. Chitneni, David A. Rotsch, Russell Z. Szmulewitz, Chin-Tu Chen
Publikováno v:
Molecules, Vol 28, Iss 16, p 6041 (2023)
In the field of nuclear medicine, the β+ -emitting 43Sc and β− -emitting 47Sc are promising candidates in cancer diagnosis and targeted radionuclide therapy (TRT) due to their favorable decay schema and shared pharmacokinetics as a true theranost
Externí odkaz:
https://doaj.org/article/d2d85dab6fef4b49ba4943ebf7d7c673
Autor:
Jeffrey S. Souris, Lara Leoni, Hannah J. Zhang, Ariel Pan, Eve Tanios, Hsiu-Ming Tsai, Irina V. Balyasnikova, Marc Bissonnette, Chin-Tu Chen
Publikováno v:
Nanomaterials, Vol 13, Iss 4, p 673 (2023)
Photodynamic therapy (PDT), the use of light to excite photosensitive molecules whose electronic relaxation drives the production of highly cytotoxic reactive oxygen species (ROS), has proven an effective means of oncotherapy. However, its applicatio
Externí odkaz:
https://doaj.org/article/a72c74d1fa3a445982e75c854b77d986
Autor:
Inna Gertsenshteyn, Boris Epel, Amandeep Ahluwalia, Heejong Kim, Xiaobing Fan, Eugene Barth, Marta Zamora, Erica Markiewicz, Hsui-Ming Tsai, Subramanian Sundramoorthy, Lara Leoni, John Lukens, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Mihai Giurcanu, Brian Roman, Gregory Karczmar, Chien-Min Kao, Howard Halpern, Chin-Tu Chen
Publikováno v:
European journal of nuclear medicine and molecular imaging. 49(12)
To identify the optimal threshold insup18/supF-fluoromisonidazole (FMISO) PET images to accurately locate tumor hypoxia by using electron paramagnetic resonance imaging (pOsub2/subEPRI) as ground truth for hypoxia, defined by pOsub2/sub[Formula: see
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8d754e3211b70055144e21c0c193f
https://pubmed.ncbi.nlm.nih.gov/35792927
https://pubmed.ncbi.nlm.nih.gov/35792927
Autor:
Hsiu-Ming Tsai, Hannah J. Zhang, Raymond E. Moellering, Shaghayegh Fathi, David C McCutcheon, Chin-Tu Chen, Gang Li, Jae Won Chang, Mohammed Bhuiyan, Richard Freifelder, Lara Leoni
Publikováno v:
Angew Chem Int Ed Engl
Herein, we report the development of an 18 F-labeled, activity-based small-molecule probe targeting the cancer-associated serine hydrolase NCEH1. We undertook a focused medicinal chemistry campaign to simultaneously preserve potent and specific NCEH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0d894cf34974f958333d2dc1557d9d
https://doi.org/10.1002/anie.202004762
https://doi.org/10.1002/anie.202004762
Autor:
Jae Won Chang, Mohammed Bhuiyan, Hsiu‐Ming Tsai, Hannah J. Zhang, Gang Li, Shaghayegh Fathi, David C. McCutcheon, Lara Leoni, Richard Freifelder, Chin‐Tu Chen, Raymond E. Moellering
Publikováno v:
Angewandte Chemie. 132:15273-15277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90d27938d596df29ff438686a271a48
https://doi.org/10.1002/ange.202004762
https://doi.org/10.1002/ange.202004762
Autor:
Samuel Mitchell, Lara Leoni, Willard W. Sharp, Yong-Hu Fang, Chin-Tu Chen, Alaa Ousta, Hsiu-Ming Tsai, Hannah J. Zhang, Lin Piao
Publikováno v:
Neurocritical Care. 34:64-72
BackgroundCardiac arrest (CA) patients who survived by cardiopulmonary resuscitation (CPR) can present different levels of neurological deficits ranging from minor cognitive impairments to persistent vegetative state and brain death. The pathophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0be9711dfc45ea0a7a8d8c14be575c
https://doi.org/10.1007/s12028-020-00984-6
https://doi.org/10.1007/s12028-020-00984-6
Autor:
Vladimir Ilievski, Yale Cho, Priya Katwala, Heriberto Rodriguez, Margaret Tulowiecka, David Kurian, Lara Leoni, John W Christman, Terry G Unterman, Keiko Watanabe
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136502 (2015)
Results from epidemiological studies indicate a close association between periodontitis and type 2 diabetes mellitus. However, the mechanism linking periodontitis to glucose intolerance (GI) and insulin resistance (IR) is unknown. We therefore tested
Externí odkaz:
https://doaj.org/article/b0e43d16db3b4feaa6064250df461ea0
Publikováno v:
Sensors, Vol 2, Iss 3, Pp 111-120 (2002)
In recent years, rapid advancements have been made in the biomedical applications of micro and nanotechnology. While the focus of such technology has primarily been on in vitro analytical and diagnostic tools, more recently, in vivo therapeutic and s
Externí odkaz:
https://doaj.org/article/6bd78e0f63f44683ac0df2f2d50ada8c
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57635 (2013)
In this study we aim to boost the functional output of the intra-kidney islet transplantation for diabetic patients using a tissue engineered polymeric scaffold. This highly porous electrospun scaffold featured randomly distributed fibers composed of
Externí odkaz:
https://doaj.org/article/cbee340db60e45e283469d20cda9a9a1
Autor:
Inna, Gertsenshteyn, Boris, Epel, Eugene, Barth, Lara, Leoni, Erica, Markiewicz, Hsiu-Ming, Tsai, Xiaobing, Fan, Mihai, Giurcanu, Darwin, Bodero, Marta, Zamora, Subramanian, Sundramoorthy, Heejong, Kim, Richard, Freifelder, Mohammed, Bhuiyan, Anna, Kucharski, Gregory, Karczmar, Chien-Min, Kao, Howard, Halpern, Chin-Tu, Chen
Publikováno v:
Radiol Imaging Cancer
PURPOSE: To enhance the spatial accuracy of fluorine 18 ((18)F) misonidazole (MISO) PET imaging of hypoxia by using dynamic contrast-enhanced (DCE) MR images as a basis for modifying PET images and by using electron paramagnetic resonance (EPR) parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16f48c6a3dd5ad393b5221e6027f3c31
https://pubmed.ncbi.nlm.nih.gov/33817651
https://pubmed.ncbi.nlm.nih.gov/33817651