Tibetan PHD2 , an allele with loss-of-function properties

Autor: Song, Daisheng, Navalsky, Bradleigh E., Guan, Wei, Ingersoll, Cassandra, Wang, Tao, Loro, Emanuele, Eeles, Lydia, Matchett, Kyle B., Percy, Melanie J., Walsby-Tickle, John, McCullagh, James S. O., Medina, Reinhold J., Khurana, Tejvir S., Bigham, Abigail W., Lappin, Terence R., Lee, Frank S.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun 01. 117(22), 12230-12238.

Externí odkaz: https://www.jstor.org/stable/26931268

Regulation of human metabolism by hypoxia-inducible factor

Autor: Formenti, Federico, Constantin-Teodosiu, Dumitru, Emmanuel, Yaso, Cheeseman, Jane, Dorrington, Keith L., Edwards, Lindsay M., Humphreys, Sandy M., Lappin, Terence R. J., McMullin, Mary F., McNamara, Christopher J., Mills, Wendy, Murphy, John A., O'Connor, David F., Percy, Melanie J., Ratcliffe, Peter J., Smith, Thomas G., Treacy, Marilyn, Frayn, Keith N., Greenhaff, Paul L., Karpe, Fredrik, Clarke, Kieran, Robbins, Peter A., Kaelin, William G.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2010 Jul . 107(28), 12722-12727.

Externí odkaz: https://www.jstor.org/stable/20724321

A Family with Erythrocytosis Establishes a Role for Prolyl Hydroxylase Domain Protein 2 in Oxygen Homeostasis

Autor: Percy, Melanie J., Zhao, Quan, Flores, Adrian, Harrison, Claire, Lappin, Terence R. J., Maxwell, Patrick H., McMullin, Mary Frances, Lee, Frank S.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2006 Jan . 103(3), 654-659.

Externí odkaz: https://www.jstor.org/stable/30049052

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Erythropoietin drives breast cancer progression by activation of its receptor EPOR

Autor: Chan, Ka Kui, Matchett, Kyle B, Coulter, Jonathan A, Hiu-Fung, Yuen, McCrudden, Cian M, Zhang, Shu-Dong, Irwin, Gareth W, Davidson, Matthew A., Rülicke, Thomas, Schober, Sophie, Hengst, Ludger, Jaekel, Heidelinde, Platt-Higgins, Angela, Rudland, Philip S, Mills, Ken I, Maxwell, Perry, El-Tanani, Mohamed, Lappin, Terence R

Publikováno v: ONCOTARGET
Chan, K K, Matchett, K B, Coulter, J A, Hiu-Fung, Y, McCrudden, C M, Zhang, S-D, Irwin, G W, Davidson, M A, Rülicke, T, Schober, S, Hengst, L, Jaekel, H, Platt-Higgins, A, Rudland, P S, Mills, K I, Maxwell, P, El-Tanani, M & Lappin, T R 2017, ' Erythropoietin drives breast cancer progression by activation of its receptor EPOR ', Oncotarget, vol. 8, no. 24, pp. 38251-38263 . https://doi.org/10.18632/oncotarget.16368

Breast cancer is a leading cause of cancer-related deaths. Anemia is common in breast cancer patients and can be treated with blood transfusions or with recombinant erythropoietin (EPO) to stimulate red blood cell production. Clinical studies have in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b1f8e25c555837138618dd7b60a241e1